Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Bioequivalence Study of Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 Mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 Mg [Phase 1]
Phase 1 bioequivalence study of Macitentan and Tadalafil 10 mg/40 mg film-coated tablets (PrOpsynvi) has completed, assessing equivalence fo…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory Failure
This clinical trial update describes a comparison of high-flow nasal cannula versus noninvasive ventilation for patients with pulmonary arte…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH) [Phase 2, Phase 3]
AAV-101 (Dry Powder Inhaled Imatinib) trial for pulmonary arterial hypertension (Phase 2/3) funded by Aerovate Therapeutics has been termina…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: A Study of Selexipag Assessing Right Ventricular Remodeling in Pulmonary Arterial Hypertension by Cardiac Magnetic Resonance Imaging [Phase 4]
Phase 4 trial of Selexipag in pulmonary arterial hypertension was terminated; results were posted, assessing right ventricular remodeling vi…
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension (PAH)
This is a completed non-interventional postauthorization safety study evaluating Ventavis (iloprost) for pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Subcutaneous Elafin in Healthy Subjects [Phase 1]
Phase 1 trial evaluating subcutaneous elafin in healthy subjects has completed, focusing on safety and pharmacokinetics.
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mg [Phase 1]
Phase 1 trial evaluating a fixed-dose combination tablet of macitentan and tadalafil (10 mg/40 mg) branded as PrOpsynvi for pulmonary arteri…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial evaluating repurposing a histamine antagonist for pulmonary arterial hypertension and associated right heart failure;…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil [Phase 3]
Phase 3 results update on the safety and pharmacology of dry powder inhaled treprostinil for pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Medication Reconciliation in Pulmonary Hypertension
A clinical trial evaluating medication reconciliation in pulmonary hypertension has completed, covering conditions such as pulmonary hyperte…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Bioequivalence Study to Compare Bosentan 32 mg Dispersible Tablets Versus Tracleer® 32 mg Tablets [Phase 1]
This Phase 1 bioequivalence study compares Bosentan 32 mg dispersible tablets to Tracleer 32 mg tablets in patients with Pulmonary Arterial …
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Spironolactone Therapy in Chronic Stable Right HF Trial [Phase 4]
A Phase 4 clinical trial assessing spironolactone therapy in patients with chronic stable right heart failure, including those with pulmonar…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With Hypoxemia [Phase 2]
Phase 2 clinical trial update evaluating whether supplemental oxygen improves six-minute walk distance in hypoxemic patients with pulmonary …
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Effects of UE Aerobic Exercise on Exercise Capacity and PA in Patients With Pulmonary Arterial Hypertension. [NA]
This clinical trial evaluated whether upper-extremity aerobic exercise improves exercise capacity and physical activity in patients with pul…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Bleeding Frequency Under Anticoagulant Treatment in Pulmonary Hypertension
This clinical trial update discusses the frequency of bleeding events in patients with pulmonary arterial hypertension who are receiving ant…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Exercise Hemodynamic, Right Ventricular Coupling and Echocardiography in Pulmonary Hypertension
Completed clinical trial update evaluating exercise hemodynamics, right ventricular coupling, and echocardiography in pulmonary hypertension…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Right Atrial Fibrosis in Pulmonary Hypertension
A ClinicalTrials.gov update indicates a completed study on right atrial fibrosis in pulmonary hypertension, including chronic thromboembolic…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Pulmonary Hypertension and Anastrozole Trial [Phase 2]
Phase 2 trial evaluating anastrozole for pulmonary arterial hypertension has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients [Phase 4]
A Phase 4 trial comparing initial triple therapy including parenteral treprostinil versus initial double oral therapy in patients with pulmo…
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - PDE5
The DREAM study evaluating a phosphodiesterase-5 inhibitor for Alzheimer's medicines has completed data analysis, with results posted on 202…
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: A Study to Investigate the Efficacy of PADN to Improved Functional Capacity and Hemodynamics in Patients With PAH [Phase 4]
Phase 4 trial investigating PADN for improving functional capacity and hemodynamics in pulmonary arterial hypertension was terminated.
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: REstoration of VItamin D in Pulmonary Arterial Hypertension [Phase 4]
Phase 4 clinical trial investigating restoration of vitamin D in patients with pulmonary arterial hypertension and vitamin D deficiency; not…
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Anti-CD20 Antibodies for Treatment of SLE-PAH [Phase 4]
Phase 4 clinical trial update evaluating anti-CD20 antibodies for treatment of systemic lupus erythematosus-associated pulmonary arterial hy…
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) [Phase 3]
Phase 3 clinical study comparing macitentan and tadalafil monotherapies with a fixed-dose combination in pulmonary arterial hypertension. Re…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH) [Phase 2]
Phase 2 trial update for GB002 in adults with pulmonary arterial hypertension has completed with results posted.