Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension [Phase 3]
A Phase 3 trial comparing monotherapy versus combination therapy for pediatric pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT) [Phase 3]
Open-label extension study PROSERA-EXT of seralutinib in adults with pulmonary arterial hypertension is ongoing in Phase 3, with the status …
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: PNEUMOSTEM® for Improving Respiratory Outcomes in Very Premature Infants Diagnosed With Early Pulmonary Arterial Hypertension [Phase 1]
A Phase 1 trial of PNEUMOSTEM for improving respiratory outcomes in very premature infants with early pulmonary arterial hypertension; the s…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH [Phase 2]
Phase 2 clinical trial update on the efficacy and safety of riociguat for incipient pulmonary vascular disease as an early indicator for pul…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Dapagliflozin in Pulmonary Arterial Hypertension [Phase 2]
Phase 2 clinical trial evaluating dapagliflozin for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension has co…
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Extension Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension Participants [Phase 2]
This update reports that the Phase 2 extension study of LTP001 in pulmonary arterial hypertension has been terminated. Results from the term…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Incorporating the Venous Excess Ultrasound Score (VExUS Score) Into Contemporary Haemodynamic Risk Assessment in Pulmonary Arterial Hypertension: The INVEXUS-PAH Study
Completed clinical trial evaluating the Venous Excess Ultrasound Score (VExUS) as part of haemodynamic risk assessment in pulmonary arterial…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD) [NA]
A completed University of Zurich study compared exercise performance in pulmonary vascular disease patients when breathing ambient air versu…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) (MK-7962-024) [Phase 2]
Merck's sotatercept (MK-7962) completed a Phase 2 trial investigating its use in pulmonary arterial hypertension (PAH).
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION) [Phase 2]
Phase 2 clinical study update for sotatercept (MK-7962) in pulmonary arterial hypertension; the LIGHTRAY EXTENSION study is currently active…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension [Phase 2]
A Phase 2 trial evaluating treprostinil for interstitial lung disease-associated pulmonary hypertension has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: The Effect of Slow-Paced Breathing on Patient Outcomes in Pulmonary Arterial Hypertension [NA]
A completed study from Ege University evaluated whether slow-paced breathing impacts outcomes in patients with pulmonary arterial hypertensi…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Effects of DHEA in Pulmonary Hypertension [Phase 2]
A Phase 2 trial evaluating the effects of dehydroepiandrosterone (DHEA) in patients with pulmonary arterial hypertension has completed and r…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension [Phase 3]
A Phase 3 trial evaluating macitentan in Japanese pediatric participants with pulmonary arterial hypertension has completed and posted resul…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Safety and Efficacy of Nebulized Nitroglycerin in Pulmonary Arterial Hypertension [NA]
A completed study evaluating the safety and efficacy of nebulized nitroglycerin in patients with pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia [Phase 2, Phase 3]
Phase 2/3 trial evaluating the effect of L-glutamine on pulmonary arterial pressure in patients with non-transfusion-dependent thalassemia. …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension. [Phase 4]
This document describes a Phase 4 long-term extension study of riociguat in patients with symptomatic pulmonary arterial hypertension. It ai…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Safety and Efficacy of Pulmonary Artery Denervation in Patients With Pulmonary Arterial Hypertension [NA]
A completed clinical trial assesses safety and efficacy of pulmonary artery denervation for pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study). [Phase 2]
A Phase 2 trial evaluating KER-012 in combination with background therapy for adults with pulmonary arterial hypertension has completed, ass…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Vardenafil Inhaled for Pulmonary Arterial Hypertension PRN Phase 2B Study [Phase 2]
Respira Therapeutics completed a Phase 2B trial evaluating inhaled vardenafil for pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Inspiratory Muscle Training in Pulmonary Hypertension [NA]
Completed clinical trial evaluating inspiratory muscle training in patients with pulmonary hypertension, including chronic thromboembolic pu…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Efficacy and Safety of Treprostinil in Intermediate-Risk Pulmonary Arterial Hypertension [Phase 2]
This clinical trial update discusses a Phase 2 study evaluating the efficacy and safety of treprostinil in patients with intermediate-risk p…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Pharmacokinetics, Safety and Tolerability of Concurrent Doses of BIA 5-1058 and Furosemide [Phase 1]
Phase 1 study evaluating pharmacokinetics, safety and tolerability of concurrent dosing of BIA 5-1058 with furosemide in pulmonary arterial …
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH [Phase 4]
Phase 4 study assessing riociguat's effects on right ventricular size and function in pulmonary arterial hypertension and chronic thromboemb…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH) [Phase 3]
A Phase 3 trial in children with pulmonary arterial hypertension tests whether macitentan delays disease progression; the study has complete…