Pulmonary Arterial Hypertension
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CLINICAL_TRIALS trial_result · 2011-09-23Clinical Trial Update: Early Therapy of Pulmonary Arterial Hypertension [NA]
This entry reports a completed clinical trial evaluating early therapy for pulmonary arterial hypertension. The trial was sponsored by the M…
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CLINICAL_TRIALS trial_result · 2011-08-30Clinical Trial Update: Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class II [Phase 3]
Phase 3 trial update reporting efficacy and safety data for oral bosentan in patients with pulmonary arterial hypertension class II.
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Placebo Controlled Trial of Bosentan in Scleroderma Patients [Phase 2]
A phase 2 placebo-controlled trial of bosentan in patients with systemic sclerosis and pulmonary hypertension was terminated; results were p…
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CLINICAL_TRIALS trial_result · 2011-06-28Clinical Trial Update: Effects of Iloprost Treatment in Adult Patients With Pulmonary Arterial Hypertension Related to Congenital Heart Disease
Clinical trial update on using iloprost to treat adults with pulmonary arterial hypertension associated with congenital heart disease.
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CLINICAL_TRIALS trial_result · 2011-06-23Clinical Trial Update: Biomarkers in the Diagnosis and Assessment of Pulmonary Arterial Hypertension (PAH) [NA]
A Northwell Health-sponsored clinical trial evaluating biomarkers for diagnosing and assessing pulmonary arterial hypertension has completed…
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CLINICAL_TRIALS trial_result · 2011-05-27Clinical Trial Update: Biomarkers in the Evaluation of Chronic Lung Disease
A completed clinical trial from Northwell Health evaluating biomarkers for chronic lung diseases, including pulmonary hypertension, pulmonar…
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: To Assess The Efficacy and Safety Of Oral Sildenafil in the Treatment of Pulmonary Arterial Hypertension. [Phase 4]
Phase 4 trial updating the efficacy and safety of oral sildenafil for pulmonary arterial hypertension, terminated with results posted in 201…
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CLINICAL_TRIALS trial_result · 2011-04-19Clinical Trial Update: Comparative Bioavailability of Treprostinil Diethanolamine Manufactured by Two Independent Facilities [Phase 1]
Phase 1 study comparing the bioavailability of treprostinil diethanolamine produced at two independent facilities. The study has completed.
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CLINICAL_TRIALS trial_result · 2011-04-04Clinical Trial Update: Hypertension Study of Ventavis® Inhalation Therapy in the Treatment of Patients With Pulmonary Arterial Hypertension (VENIS)
The VENIS trial evaluating Ventavis inhalation therapy for pulmonary arterial hypertension has completed. This update notes the trial status…
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CLINICAL_TRIALS trial_result · 2011-04-01Clinical Trial Update: Trial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH) [Phase 2]
Phase 2 trial evaluating iloprost inhaled solution as add-on therapy to bosentan in patients with pulmonary arterial hypertension has comple…
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CLINICAL_TRIALS trial_result · 2010-11-19Clinical Trial Update: Safety and Efficacy Study of Ambrisentan in Subjects With Pulmonary Hypertension [Phase 3]
This document reports the completion and posting of results from a Phase 3 safety and efficacy trial of ambrisentan in subjects with pulmona…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: A Bioavailability Study Comparing Treprostinil Diethanolamine Oral Tablets and Oral Solution in Healthy Volunteers [Phase 1]
This Phase 1 study compares the bioavailability of treprostinil diethanolamine oral tablets versus oral solution in healthy volunteers. The …
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CLINICAL_TRIALS trial_result · 2010-08-23Clinical Trial Update: Pharmacokinetic Linearity and Comparative Bioavailability of Treprostinil Diethanolamine [Phase 1]
Phase 1 pharmacokinetic study evaluating the linearity of exposure and the comparative bioavailability of treprostinil diethanolamine.
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CLINICAL_TRIALS trial_result · 2010-08-13Clinical Trial Update: The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial Hypertension [Phase 3]
The Phase 3 'VISION' trial evaluating Ventavis (iloprost) inhalation with sildenafil for pulmonary arterial hypertension was terminated, wit…
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CLINICAL_TRIALS trial_result · 2010-03-30Clinical Trial Update: To Provide Sildenafil Therapy To Eligible Adult Patients With Pulmonary Arterial Hypertension For 112 Weeks
Clinical trial update describing sildenafil therapy for eligible adults with pulmonary arterial hypertension over 112 weeks; study status co…
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CLINICAL_TRIALS trial_result · 2010-03-09Clinical Trial Update: Correlation OF Hemodynamics in Pulmonary Hypertension With Perfusion Lung Scans
This document provides an update on a completed clinical trial investigating the relationship between hemodynamics in pulmonary arterial hyp…
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CLINICAL_TRIALS trial_result · 2010-03-08Clinical Trial Update: Effect of Food on the Pharmacokinetics of Oral Treprostinil [Phase 1]
Phase 1 trial evaluating how food intake affects the pharmacokinetics of oral treprostinil in patients with pulmonary arterial hypertension …
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CLINICAL_TRIALS trial_result · 2010-03-08Clinical Trial Update: ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH) [Phase 3]
Phase 3 trial update on ambrisentan (Letairis) in adults with moderate to severe pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2010-03-08Clinical Trial Update: Effect of Esomeprazole on the Pharmacokinetics of Oral Treprostinil [Phase 1]
A Phase 1 study assessing the impact of esomeprazole on the pharmacokinetics of oral treprostinil has been completed.
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CLINICAL_TRIALS trial_result · 2010-02-12Clinical Trial Update: The Efficacy and Safety of Vardenafil in the Treatment of Pulmonary Arterial Hypertension [Phase 3]
Phase 3 trial evaluating the efficacy and safety of vardenafil in treating pulmonary arterial hypertension. The study status is completed.
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CLINICAL_TRIALS trial_result · 2009-11-10Clinical Trial Update: Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial Hypertension [Phase 2]
Phase 2 trial evaluating the efficacy, safety and pharmacokinetics of GSK1325760A in pulmonary arterial hypertension has completed, with res…
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CLINICAL_TRIALS trial_result · 2009-07-21Clinical Trial Update: A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension. [Phase 3]
A Phase 3 randomized, double-blind, placebo-controlled study evaluated sildenafil in children with pulmonary arterial hypertension; trial co…
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CLINICAL_TRIALS trial_result · 2009-04-17Clinical Trial Update: Post-Marketing Surveillance of Ventavis® in Chinese Patients With Primary Pulmonary Hypertension (PPH)
A post-marketing surveillance study evaluating Ventavis (iloprost) in Chinese patients with pulmonary arterial hypertension has been complet…
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CLINICAL_TRIALS trial_result · 2009-04-16Clinical Trial Update: Study of BSF 208075 Evaluating Exercise Capacity in Patients With Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 trial evaluating BSF 208075 on exercise capacity in patients with pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2009-04-16Clinical Trial Update: Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension. [Phase 3]
Phase 3 trial evaluating ambrisentan in pulmonary arterial hypertension has completed.