Prostate Cancer
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Androgen Deprivation Therapy Prior to Prostatectomy for Patients with Intermediate and High Risk Prostate Cancer [NA]
This clinical trial investigated androgen deprivation therapy before prostatectomy in men with intermediate- and high-risk prostate cancer; …
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: Partial Prostatectomy for Prostate Cancer [NA]
This clinical trial update concerns partial prostatectomy for prostate cancer. The status is unknown and no specific drugs are listed.
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Study of 89Zr-DFO-MSTP2109A in Patients With Prostate Cancer [Phase 1, Phase 2]
Results from a Phase 1/2 clinical trial of the radiolabeled imaging agent 89Zr-DFO-MSTP2109A in prostate cancer have been posted; the study …
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: 64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA) [Phase 1, Phase 2]
Phase 1/2 trial of 64Cu-SAR-bisPSMA for identifying recurrence of prostate cancer has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: CyberKnife® as Monotherapy or Boost SBRT for Intermediate or High Risk Localized Prostate Cancer [NA]
This completed trial evaluated CyberKnife-based radiotherapy as monotherapy or as a boost with SBRT for intermediate- to high-risk localized…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Influence of Electronic Patient Reported Outcomes (ePROMs) in Surgical Therapy for Prostate Cancer on Postoperative Outcome [NA]
This entry reports a clinical trial investigating the influence of electronic patient-reported outcomes (ePROMs) in surgical therapy for pro…
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: FIRMAGON® Intensive Drug Monitoring
Results from an intensive drug monitoring study of FIRMAGON (degarelix) in prostate cancer have been posted.
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway [Phase 1]
This clinical trial update describes a Phase 1 study of the PARP inhibitor DAT-2645 monotherapy for advanced/metastatic solid tumors harbori…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: All-in-One Prostate Cancer Staging with MRI
A clinical trial update for an all-in-one MRI-based staging approach in prostate cancer, sponsored by the European Institute of Oncology; th…
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CLINICAL_TRIALS research · 2024-09-26Clinical Trial Update: ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6-Vulnerable) [Phase 3]
This Phase 3 clinical trial update describes PEACE6-Vulnerable, a study evaluating androgen deprivation therapy with or without darolutamide…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Addition of Opaganib to Androgen Antagonists in Patients With mCRPC [Phase 2]
Phase 2 trial results evaluating the addition of opaganib to androgen antagonists in patients with metastatic castration-resistant prostate …
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 bioequivalence study comparing the proposed talazoparib capsule formulation to the current formulation, plus a food-effect assessmen…
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CLINICAL_TRIALS withdrawal · 2024-09-25Clinical Trial Update: 18F-rhPSMA-7.3 PET/MRI in Prostate Cancer Active Surveillance: a Pilot Study [EARLY_Phase 1]
An EARLY Phase 1 pilot study evaluating the 18F-rhPSMA-7.3 PET/MRI tracer for prostate cancer under active surveillance has been withdrawn.
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: 68Ga-AAZTA-NI-093 PET/CT: First-in-human Study [EARLY_Phase 1]
First-in-human PET/CT study of the radiopharmaceutical 68Ga-AAZTA-NI-093 for prostate cancer, currently in EARLY_PHASE1 and enrolling at the…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Study of Patients Receiving High-Dose Rate Brachytherapy [Phase 2]
A Phase 2 study of high-dose-rate brachytherapy in patients with cervical cancer, endometrial cancer, esophageal cancer, prostate cancer, an…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Prostate Imaging Using MRI +/- Contrast Enhancement [NA]
Clinical trial update on MRI-based imaging for prostate cancer with optional contrast enhancement. The study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Finasteride and Flutamide in Pre-surgical Trial in Prostate Cancer. [Phase 2, Phase 3]
Clinical trial update reports completion of phase 2 and phase 3 studies evaluating finasteride and flutamide in pre-surgical treatment for p…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Developing an Imaging-Based Tool to Identify Areas for Prostate Cancer Biopsy [NA]
This clinical trial update reports results for an imaging-based tool intended to identify biopsy areas in prostate cancer; the study has com…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: PSMA-PET/CT for Prostate Cancer [Phase 1]
This update reports the completion of a Phase 1 trial evaluating PSMA-PET/CT imaging in prostate cancer, sponsored by University Hospital Gh…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients [NA]
A completed clinical trial update examining whether different CBT-I doses affect innate immunity, insomnia, and fatigue in patients with bre…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Conventional Androgen Deprivation Therapy (ADT) With or Without Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT [Phase 3]
A Phase 3 trial evaluating conventional androgen deprivation therapy with or without Abiraterone acetate plus prednisone and apalutamide in …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: 18F-PSMA-1007 PET/CT Imaging in Patients with Biochemically Recurrent or High-risk Prostate Cancer [Phase 2]
A Phase 2 clinical trial evaluating 18F-PSMA-1007 PET/CT imaging in biochemically recurrent or high-risk prostate cancer has completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT [Phase 3]
Phase 3 clinical trial comparing 5-fraction prostate SBRT alone to 5-fraction prostate SBRT with pelvic nodal irradiation. The study is curr…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Assessing Depression in a Geriatric Cancer Population
A clinical trial assessing depression in geriatric cancer patients has completed. The study included participants with breast cancer and pro…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: To Live Better After Prostate Cancer Treatment: [NA]
Karolinska Institutet is sponsoring a trial to improve quality of life after prostate cancer treatment, and the study is currently recruitin…