Prostate Cancer
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Abemaciclib in Combination With Androgen Deprivation Therapy for Locally Advanced Prostate Cancer [Phase 2]
Phase 2 trial update evaluating Abemaciclib with androgen deprivation therapy for locally advanced prostate cancer; the study was terminated…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Evaluation of PSMA-based PET as an Imaging Biomarker in Prostate Cancer [EARLY_Phase 1]
The document notes the completion of an early-phase study evaluating PSMA-based PET imaging as a biomarker in advanced prostate cancer.
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Telephone Paramedical Support Prior to the Radiotherapy Simulation Scanner for Patients with Prostate Cancer [NA]
Clinical trial update noting completion of a study evaluating telephone paramedical support prior to radiotherapy simulation for patients wi…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors [Phase 1, Phase 2]
Valerio Therapeutics terminated a Phase 1/2 trial of VIO-01 in patients with advanced or metastatic solid tumors, including breast, ovarian,…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer [Phase 1, Phase 2]
Status update on a Phase 1/2 clinical trial evaluating ARV-766 taken orally in men with metastatic prostate cancer, sponsored by Novartis.
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: An Investigational Scan (7 Tesla MRI) in Diagnosing Cognitive Impairment in Patients With Non-Metastatic Prostate Cancer [NA]
A completed clinical trial evaluating whether a 7 Tesla MRI can help diagnose cognitive impairment in men with non-metastatic prostate cance…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Imaging Guided Surgery to Improve the Detection of Lymph Node Metastases in Prostate Cancer Patients [Phase 2]
A Phase 2 trial evaluating imaging-guided surgery to improve detection of lymph node metastases in prostate cancer; the study has completed.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Focal HDR Brachytherapy Boost to Stereotactic Radiotherapy [Phase 2]
Phase 2 clinical trial evaluating focal HDR brachytherapy boost to stereotactic radiotherapy for prostate cancer; the study is currently rec…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: PSMA PET/CT Guided Intensification of Therapy in Patients at Risk of Advanced Prostate Cancer [Phase 3]
Phase 3 trial evaluating PSMA PET/CT-guided intensification of therapy for patients at risk of advanced prostate cancer. The study is curren…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Multi-modality Imaging (PCa) Using Sodium MRI and PSMA PET in Men Pre-prostatectomy [Phase 2]
This document reports on a Phase 2 clinical trial evaluating multi-modality imaging for prostate cancer using sodium MRI and PSMA PET in men…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Comparison of HDR vs. LDR Brachytherapy as Monotherapy for Intermediate Risk Prostate Cancer [Phase 3]
Phase 3 clinical trial comparing high-dose-rate (HDR) versus low-dose-rate (LDR) brachytherapy as monotherapy for intermediate-risk prostate…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage [NA]
This clinical trial update describes a study characterizing microbiological and genetic features in prostate cancer and examining their asso…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: PEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-II) [Phase 4]
Phase 4 clinical trial PEHAB-II is evaluating penile rehabilitation after nerve-sparing robot-assisted radical prostatectomy in men with ere…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Stereotactic Re-irradiation of Local Recurrences of Prostate Cancer After Radiotherapy [Phase 2]
This item announces a Phase 2 clinical trial investigating stereotactic re-irradiation for local recurrences of prostate cancer after prior …
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: PSMA-PET Guided Radiotherapy [Phase 2, Phase 3]
This entry describes an ongoing Phase 2/3 trial evaluating PSMA-PET guided radiotherapy for prostate cancer, with the study currently listed…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Study of Diagnostic Performance of [18F]CTT1057 in BCR [Phase 3]
Novartis completed a Phase 3 trial evaluating the diagnostic performance of the radiopharmaceutical [18F]CTT1057 in detecting biochemical re…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: [18F]Florastamin PET/CT Imaging Examination in Patients With Suspected Recurrent or Metastatic Prostate Cancer [Phase 3]
This Phase 3 trial evaluates the PET imaging agent [18F]Florastamin for detecting suspected recurrent or metastatic prostate cancer; FutureC…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Evaluate the Clinical Usefulness of [F-18]Florastamin PET/CT Imaging Diagnosis Compared to MRI Diagnosis [Phase 3]
Phase 3 clinical trial evaluating the clinical usefulness of [F-18]Florastamin PET/CT imaging for diagnosing high-risk prostate cancer and c…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: New Treatment Modalities for Localized Prostate Cancer
A clinical trial update describing new treatment modalities under investigation for localized prostate cancer. The study is currently active…
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CLINICAL_TRIALS withdrawal · 2025-03-12Clinical Trial Update: Real-life Experience in Brazil in Patients With Castration-resistant Prostate Cancer Treated With Olaparib+Abiraterone
Clinical trial update reports real-world Brazilian experience in castration-resistant prostate cancer patients treated with the combination …
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Cancer of the Prostate Treated With Focal Implantation of a RadioactivE Source [NA]
A clinical trial at Herlev Hospital is evaluating focal implantation of a radioactive source to treat prostate cancer, with enrollment by in…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: RegisterPROS - a Registry for Prostate Cancers
Update on the RegisterPROS registry for prostate cancer; sponsor Wren Laboratories LLC reports enrollment by invitation.
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: PSA Biochemical Response as Prognostic Factor in Metastatic Castration-Sensitive Prostate Cancer
This clinical trial investigates whether PSA biochemical response can serve as a prognostic factor in metastatic castration-sensitive prosta…
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FDA label_change · 2025-03-11FDA Approved: TRELSTAR — Supplemental Application (Verity Pharmaceuticals Inc.)
FDA supplemental application for TRELSTAR (triptorelin pamoate) submitted by Verity Pharmaceuticals Inc. to update labeling, potentially exp…
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FDA approval · 2025-03-11FDA Approved: BICALUTAMIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved a supplemental application for bicalutamide from Sun Pharmaceutical Industries, updating the existing generic approval.