Prostate Cancer
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer [EARLY_Phase 1]
Early-phase study to determine the preferred dose of lisinopril to prevent urinary toxicity after radiotherapy in men with prostate cancer, …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs [Phase 1, Phase 2]
This Phase 1/2 clinical trial investigates the safety and preliminary effectiveness of AZD9750 in metastatic prostate cancer, with no recrui…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS) [NA]
The ProGRESS study (Prostate Cancer, Genetic Risk, and Equitable Screening) is investigating prostate cancer genetics and screening equity a…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Minimal Residual Disease Used in Predicting Therapeutic Efficacy in Metastatic Hormone-sensitive Prostate Cancer
This clinical trial assesses whether minimal residual disease can predict therapeutic efficacy in metastatic hormone-sensitive prostate canc…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial [NA]
A micro-randomized trial testing dosing of physical activity among older cancer survivors with chronic pain is currently recruiting. The tri…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Impact of Radical Prostatectomy as Primary Treatment in Patients With Prostate Cancer With Limited Bone Metastases [NA]
This clinical trial update notes that the study evaluating radical prostatectomy as the primary treatment for prostate cancer with limited b…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Role of Lymphnode Dissection in Men With Prostate Cancer Treated With Radical Prostatectomy [NA]
Clinical trial update (status: active not recruiting) evaluating the role of lymph node dissection in men with prostate cancer treated with …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial [NA]
The PRIMER trial, sponsored by the University of Southern California, compares an MRI-based machine learning approach to radiologist MRI rea…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Phase III Randomized International Open Label Clinical Trial of Treatment Intensification With Docetaxel Plus Apalutamide in Patients With Metastatic Hormone-sensitive Prostate Cancer Who Did Not Achieve a Deep PSA Response After Initial Treatment With Apalutamide: REINFORCE Trial. [Phase 3]
This clinical trial update outlines the Phase III REINFORCE trial evaluating intensification with docetaxel plus apalutamide in metastatic h…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating TJ101 for safety, pharmacokinetics, and efficacy in advanced/metastatic solid tumors, including non-small …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Navigation, Outcomes and Quality-of-life in Prostate Cancer Patients Undergoing PSMA-targeted Surgery [NA]
This clinical trial update describes a study evaluating navigation, outcomes, and quality of life for prostate cancer patients undergoing PS…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Microarray Analysis of Gene Expression in Prostate Tissues
This completed study performed microarray analysis of gene expression in prostate tissues to advance understanding of prostate cancer.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Randomised Trial of Cabazitaxel, Docetaxel, Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients [Phase 2, Phase 3]
A randomized phase 2/3 trial comparing cabazitaxel, docetaxel, mitoxantrone, or satraplatin plus surgery for prostate cancer, currently recr…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Detection of Minimal Residual Disease Post-prostatectomy
This clinical trial entry describes a study evaluating detection of minimal residual disease after prostatectomy in prostate cancer and is c…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s) [NA]
An update on an ongoing clinical trial investigating early prostate cancer recurrence in patients with PSMA PET-positive unilateral pelvic l…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Men Moving Forward: A Lifestyle Program for African-American Prostate Cancer Survivors [NA]
An update on an ongoing lifestyle intervention trial for African-American prostate cancer survivors, sponsored by the Medical College of Wis…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer [Phase 2]
Phase 2 clinical trial update for an investigational imaging tracer 68Ga-PSMA-11 used to image prostate cancer; the study is currently ACTIV…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Study of Predicting Lymph Node Metastasis of High-risk Prostate Cancer by Artificial Intelligence Multi-omics Analysis
A clinical study is evaluating AI-powered multi-omics analysis to predict lymph node metastasis in high-risk prostate cancer and is currentl…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: EDRN Prostate MRI Biomarker Study
This entry notes an ongoing prostate cancer biomarker trial at University of Michigan evaluating EDRN prostate MRI biomarkers; enrollment is…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Focal or Radical Therapy: a Lesion-based Molecular Evaluation in Prostate Cancer [NA]
An ongoing clinical trial at Singapore General Hospital is evaluating focal or radical therapy for lesion-based molecular evaluation in pros…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer. [Phase 4]
A Phase 4 clinical trial from the University of Chicago is evaluating outcomes of combining darolutamide with androgen deprivation therapy i…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations [Phase 2]
A Phase 2 clinical trial update for CJNJ-67652000 in combination with prednisone to treat metastatic castration-resistant prostate cancer, i…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer [Phase 2]
A Phase 2 clinical trial is investigating MR imaging using hyperpolarized 13C-pyruvate with or without 13C,15N-urea in prostate cancer patie…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: The Impact of Androgen Ablation Therapy on Cognitive Functioning and Functional Status in Men With Prostate Cancer Age 65 and Older
This clinical trial update investigates the impact of androgen deprivation therapy on cognitive functioning and functional status in men age…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer [Phase 2]
This document provides an update on the Phase 2 SMMART-ACT precision medicine trial. It targets patients with advanced breast, ovarian, panc…