Proliferative Vitreoretinopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Study of Imaging and Molecular Biomarkers in Uncomplicated Rhegmatogenous Retinal Detachment
This clinical trial outlines an imaging and molecular biomarker evaluation in uncomplicated rhegmatogenous retinal detachment. The study is …
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy [Phase 1]
Phase 1 clinical trial update on intravitreal topotecan for proliferative vitreoretinopathy; the study assesses safety and potential efficac…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment [Phase 1, Phase 2]
A Phase 1/2 trial is evaluating topical netarsudil to prevent proliferative vitreoretinopathy in patients with Rhegmatogenous Retinal Detach…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Effects of 0.1% Nepafenac on Vitreous Inflammatory Biomarkers in Rhegmatogenous Retinal Detachment and Proliferative Vitreoretinopathy [Phase 4]
Phase 4 clinical trial evaluating the effects of 0.1% Nepafenac on vitreous inflammatory biomarkers in rhegmatogenous retinal detachment and…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Methotrexate in Retinal Detachment With Proliferative Vitreoretinopathy [NA]
Clinical trial evaluating methotrexate for retinal detachment with proliferative vitreoretinopathy has completed enrollment.
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative Vitreoretinopathy [Phase 3]
A Phase 3 trial (GUARD Trial) evaluating prevention of Proliferative vitreoretinopathy has completed with results posted in 2025.
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Intravitreal Topotecan for Prevention or Treatment of Proliferative Vitreoretinopathy in Retinal Detachment [Phase 2]
A Phase 2 clinical trial evaluating intravitreal topotecan to prevent or treat proliferative vitreoretinopathy in rhegmatogenous retinal det…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Intravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy [Phase 2]
Phase 2 trial evaluating intravitreal topotecan for repair of rhegmatogenous retinal detachment with proliferative vitreoretinopathy is curr…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Outcomes of Retinal Re-surgeries in Silicone Oil Filled Eyes
This completed clinical trial reports the outcomes of retinal re-surgeries in silicone oil–filled eyes, focusing on retinal detachment and p…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial [Phase 2]
A Phase 2 trial (FIXER) is evaluating intravitreal methotrexate to prevent proliferative vitreoretinopathy during primary retinal detachment…
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR [Phase 2, Phase 3]
A multi-center Phase 2/Phase 3 clinical trial evaluating a Rho-kinase inhibitor to reduce or prevent proliferative vitreoretinopathy in eyes…
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: "Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy" [Phase 1, Phase 2]
A clinical trial exploring methotrexate usage techniques to prevent proliferative vitreoretinopathy after retinal detachment vitrectomy is i…
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CLINICAL_TRIALS trial_result · 2024-01-19Clinical Trial Update: Intravitreal Infliximab for Proliferative Vitreoretinopathy [Phase 2]
Phase 2 clinical trial evaluating intravitreal infliximab for proliferative vitreoretinopathy has been completed.
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: Intravitreal Aflibercept for the Prevention of Proliferative Vitreoretinopathy Following Retinal Detachment Repair [Phase 2]
Phase 2 trial evaluating intravitreal aflibercept to prevent proliferative vitreoretinopathy after retinal detachment repair.
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment. [Phase 3]
Phase 3 trial evaluating prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk retina…
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: Bevacizumab Against Recurrent Retinal Detachment [Phase 2]
Phase 2 clinical trial evaluating bevacizumab for recurrent retinal detachment and proliferative vitreoretinopathy has completed with result…
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CLINICAL_TRIALS trial_result · 2020-07-22Clinical Trial Update: Repeated Methotrexate for Proliferative Vitreoretinopathy Grade C [Phase 2, Phase 3]
A clinical trial update on repeated methotrexate for proliferative vitreoretinopathy (Grade C) in Phase 2/Phase 3.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Isotretinoin for Proliferative Vitreoretinopathy [Phase 4]
Phase 4 clinical trial evaluating isotretinoin for proliferative vitreoretinopathy has completed; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Eye Injections of Bevacizumab for Lowering Risk of Scar Tissue in the Retina and Repeated Retinal Detachment. [NA]
Completed trial evaluating eye injections of bevacizumab to reduce scar tissue in the retina and prevent recurrent retinal detachment. Resul…
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Postoperative Pain Control Following Vitreoretinal Surgery [Phase 4]
Phase 4 trial update on postoperative pain control after vitreoretinal surgery conducted by Emory University; the study completed and result…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Dacorin for Proliferative Vitreoretinopathy [Phase 1, Phase 2]
A Phase 1/2 clinical trial of Dacorin for proliferative vitreoretinopathy conducted at Cairo University has completed.
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CLINICAL_TRIALS research · 2016-04-22Clinical Trial Update: Optical Coherence Tomography - Rescan During Dissection of Macular Membranes [NA]
This clinical trial update discusses using Optical Coherence Tomography rescans during dissection of macular membranes in retinal conditions…
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CLINICAL_TRIALS trial_result · 2013-06-14Clinical Trial Update: Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments [NA]
This completed clinical trial compares 1000 cSt versus 5000 cSt silicone oil for repair of complex retinal detachments.
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CLINICAL_TRIALS research · 2008-06-26Clinical Trial Update: Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR) [Phase 3]
Phase 3 trial evaluating oral colchicine combined with intravitreal dexamethasone, low molecular weight heparin, and 5-fluorouracil for prol…
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CLINICAL_TRIALS trial_result · 2007-07-12Clinical Trial Update: The Effect of 5-FU and LMW Heparin on the Rate of Retinal Redetachment After Silicone Oil Removal in Cases of PVR [Phase 3]
A Phase 3 clinical trial is evaluating whether 5-fluorouracil and low molecular weight heparin can reduce retinal redetachment after silicon…