Biliary Cholangitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis [Phase 2]
Phase 2 dose-response study for GSK2330672 in pruritus associated with primary biliary cholangitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: Ursodeoxycholic Acid Combined With Total Glucosides of Paeony in the Treatment of PBC With AIH Features 1 [Phase 4]
Phase 4 trial update evaluating ursodeoxycholic acid combined with total glucosides of paeony for primary biliary cholangitis with autoimmun…
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II [Phase 4]
Phase 4 trial update evaluating ursodeoxycholic acid with low-dose glucocorticoid for primary biliary cholangitis with autoimmune features.
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA [Phase 2]
Phase 2 clinical trial of baricitinib in participants with primary biliary cholangitis who do not respond or cannot take UDCA has been termi…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis [Phase 2]
Phase 2 study evaluating cilofexor in adults with primary biliary cholangitis without cirrhosis; study terminated with posted results in 202…
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Probiotics in PBC Patients of Poor Response to UDCA [Phase 2]
Phase 2 clinical trial evaluating probiotics in patients with primary biliary cholangitis who respond poorly to UDCA.
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients [Phase 2]
Phase 2 trial evaluating safety, tolerability, and efficacy of Tropifexor (LJN452) in patients with Primary Biliary Cholangitis has complete…
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CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) and Inadequate Response to Ursodeoxycholic Acid [Phase 2]
A Phase 2 clinical trial evaluating elafibranor for primary biliary cholangitis in patients with inadequate response to ursodeoxycholic acid…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: A Trial of 18-22mg/kg/d Ursodeoxycholic in Refractory Primary Biliary Cholangitis [Phase 4]
Phase 4 clinical trial evaluating high-dose ursodeoxycholic acid (18-22 mg/kg/day) in patients with refractory primary biliary cholangitis; …
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CLINICAL_TRIALS trial_result · 2018-04-26Clinical Trial Update: Nalfurafine Hydrochloride for Pruritus in Patients With Primary Biliary Cholangitis
A clinical trial update indicates the study of nalfurafine hydrochloride for pruritus in primary biliary cholangitis has completed.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-responders [Phase 3]
This Phase 3 trial update summarizes the study evaluating bezafibrate to achieve complete biochemical response in non-responders with primar…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus [Phase 2]
A Phase 2 study assessed safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of GSK2330672 in adults with primary …
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Phase 2 Study of NGM282 in Patients With Primary Biliary Cirrhosis [Phase 2]
Phase 2 study of NGM282 in patients with primary biliary cholangitis has completed.
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis [Phase 4]
This clinical-trial update notes the completion of a Phase 4 study assessing the effectiveness of S-adenosyl-L-methionine in patients with p…
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Phase 2b Study of NGM282 Extended Treatment in Patients With Primary Biliary Cirrhosis [Phase 2]
Phase 2b study of NGM282 for primary biliary cholangitis has completed; the update notes the trial status as COMPLETED.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: IBAT Inhibitor A4250 for Cholestatic Pruritus [Phase 2]
A Phase 2 trial of the IBAT inhibitor A4250 for cholestatic pruritus in primary biliary cholangitis was terminated.
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis [Phase 2]
Phase 2 trial evaluating rituximab, a B-cell depleting therapy, for fatigue in primary biliary cholangitis has completed.
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Fuzhenghuayu for Patients With PBC Who Had An Inadequate Response to Ursodeoxycholic Acid [Phase 3]
Phase 3 clinical trial update for Fuzhenghuayu in patients with primary biliary cholangitis who did not respond adequately to ursodeoxycholi…
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CLINICAL_TRIALS trial_result · 2016-08-24Clinical Trial Update: Pilot Study of FFP104 Dose Escalation in PBC Subjects [Phase 1, Phase 2]
Pilot dose-escalation study of FFP104 in subjects with Primary Biliary Cholangitis (Phase 1/Phase 2) with current status listed as unknown.
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT [Phase 1]
Phase 1 study assessing biliary excretion of conjugated bile acids in humans using 11C-cholylsarcosine PET/CT; the trial was completed and r…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: A Study of Efficacy and Safety of Ustekinumab in Patients With Primary Biliary Cirrhosis (PBC) Who Had an Inadequate Response to Ursodeoxycholic Acid [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of ustekinumab in patients with primary biliary cholangitis who had an inadequate respons…
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CLINICAL_TRIALS trial_result · 2014-04-04Clinical Trial Update: Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody [Phase 2]
A Phase 2 trial of NI-0801, an anti-CXCL10 monoclonal antibody, for primary biliary cholangitis was terminated.
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CLINICAL_TRIALS trial_result · 2014-03-24Clinical Trial Update: Efficacy and Safety Study of TUDCA Compare UDCA to Treatment Chronic Cholestatic Liver Disease-PBC [Phase 3]
Phase 3 efficacy and safety trial comparing tauroursodeoxycholic acid (TUDCA) with ursodeoxycholic acid (UDCA) for primary biliary cholangit…
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CLINICAL_TRIALS trial_result · 2013-12-09Clinical Trial Update: Pentoxifylline for Primary Biliary Cirrhosis [Phase 2]
Phase 2 trial results for pentoxifylline in primary biliary cholangitis have been posted following completion of the study.
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CLINICAL_TRIALS trial_result · 2013-05-20Clinical Trial Update: Safety and Efficacy of Tauroursodeoxycholic Acid Versus Ursofalk in the Treatment of Adult Primary Biliary Cirrhosis [Phase 3]
Phase 3 trial comparing Tauroursodeoxycholic acid to Ursofalk for adult primary biliary cholangitis has completed.