Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-12-19Clinical Trial Update: Effect of Oral Pregabalin on Spinal Neurotransmitters in Patients Undergoing Knee Replacement [Phase 3]
Phase 3 trial investigates the effect of oral pregabalin on spinal neurotransmitters in patients undergoing knee replacement; results have b…
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CLINICAL_TRIALS trial_result · 2012-12-18Clinical Trial Update: Non-invasive Assessment of Immediate Postoperative Analgesia Using Analgesia/Nociception Index (ANI)
The clinical trial evaluated non-invasive assessment of immediate postoperative analgesia using Analgesia/Nociception Index (ANI) in patient…
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CLINICAL_TRIALS trial_result · 2012-12-13Clinical Trial Update: Treatment of Breast Pain Using A Medication (Diclofenac) Applied to the Skin [Phase 2, Phase 3]
A Phase 2/3 trial evaluating topical diclofenac for breast pain (mastalgia) was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Evaluating Transcutaneous Electrical Nerve Stimulation for Postoperative Pain After Video-Assisted Thoracotomy Surgery [NA]
A completed clinical trial evaluated transcutaneous electrical nerve stimulation (TENS) for reducing postoperative pain after video-assisted…
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CLINICAL_TRIALS trial_result · 2012-12-10Clinical Trial Update: The Median Effective Dose (ED50) of Paracetamol and Morphine : A Study of Interaction Study [NA]
This completed clinical trial investigates the median effective dose (ED50) of paracetamol and morphine and their interaction for postoperat…
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: Analgesic Efficacy of Ultrasound-guided Transverse-abdominal Plain Blockade in Urological Surgery [Phase 4]
A Phase 4 study evaluating the analgesic efficacy of an ultrasound-guided transverse-abdominal plane blockade in urological surgery has comp…
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery [Phase 4]
Phase 4 clinical trial evaluating pregabalin for postoperative pain in women undergoing breast cancer surgery has completed.
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Reduction of Postoperative Pain, Nausea and Vomiting
A completed clinical trial investigating methods to reduce postoperative pain, nausea and vomiting.
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CLINICAL_TRIALS trial_result · 2012-10-29Clinical Trial Update: Morphine PK Subgroup Analysis [Phase 4]
This update reports results from a pharmacokinetic subgroup analysis of morphine in a Phase 4 trial for postoperative pain. The analysis exa…
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Study of the Safety, Tolerability and Analgesic Efficacy of Multiple Doses of Ketorolac Tromethamine (IN) for Postoperative Pain [Phase 2]
This entry reports the Phase 2 results of a study evaluating safety, tolerability, and analgesic efficacy of multiple doses of ketorolac tro…
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FDA approval · 2012-10-16FDA Approved: ILEVRO — Original Application (Novartis Pharmaceuticals Corporation)
FDA approved ILEVRO (nepafenac) from Novartis Pharmaceuticals Corporation as the original application for reducing postoperative pain and in…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: Comparison of Postoperative Analgesic Effect of Intrathecal Magnesium and Fentanyl Added to Bupivacaine in Patients Undergoing Lower Limb Orthopedic Surgery [Phase 1, Phase 2]
This Phase 1/2 clinical trial compared intrathecal magnesium sulfate and intrathecal fentanyl added to bupivacaine for postoperative analges…
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CLINICAL_TRIALS trial_result · 2012-10-04Clinical Trial Update: A Study to Assess Analgesic Efficacy of Intravenous Lignocaine [Phase 4]
A Phase 4 clinical trial evaluating the analgesic efficacy of intravenous lignocaine for postoperative pain, postoperative nausea and vomiti…
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FDA approval · 2012-09-05FDA Approved: KETOROLAC TROMETHAMINE — Supplemental Application (Onesource Specialty Pharma Limited)
FDA approved a supplemental application for ketorolac tromethamine from Onesource Specialty Pharma Limited. This action updates the approval…
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FDA label_change · 2012-08-20FDA Approved: KETOROLAC TROMETHAMINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental labeling application for ketorolac tromethamine (Toradol) from Mylan Pharmaceuticals, indicating a labeling upda…
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Pain After Laparoscopic Cholecystectomy With Bilateral Tranversus Abdominis Plane (TAP) Block Versus Local Anesthetic Infiltration [NA]
This update reports on a completed trial comparing bilateral TAP block versus local anesthetic infiltration for postoperative pain after lap…
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CLINICAL_TRIALS research · 2012-06-20Clinical Trial Update: Intraperitoneal Atomization of Ropivacaine During Gynecologic Laparoscopic Surgery [Phase 3]
A Phase 3 trial evaluating intraperitoneal atomization of ropivacaine during gynecologic laparoscopic surgery to manage postoperative pain; …
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CLINICAL_TRIALS research · 2012-06-06Clinical Trial Update: Pregabalin for Post-craniotomy Pain Control [NA]
This entry reports on a trial investigating pregabalin for reducing immediate and late (1- and 3-month) postoperative analgesia requirements…
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CLINICAL_TRIALS research · 2012-05-30Clinical Trial Update: Persistent Pain After Laparoscopic Inguinal Hernia Repair
The clinical trial NCT01085110 evaluating persistent pain after laparoscopic inguinal hernia repair has completed. It investigated postopera…
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of Q8003 for managing postoperative pain after bunionectomy has completed.
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty [Phase 2]
Phase 2 pilot study evaluating the efficacy and safety of Q8003 for postoperative pain after total knee arthroplasty or total hip arthroplas…
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients [Phase 2]
A Phase 2 trial comparing Q8003 to its individual components in bunionectomy patients assessed efficacy and safety for postoperative pain an…
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients [Phase 3]
A Phase 3 trial assessing the safety of Q8003 compared with morphine-equivalent doses of its oxycodone and morphine components in bunionecto…
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Double Blind Efficacy and Safety Study of Flexible-Dose vs Low-Dose Q8003 After Undergoing Primary Unilateral Total Knee Arthroplasty [Phase 3]
A Phase 3 randomized study comparing flexible-dose vs low-dose Q8003 for postoperative pain after unilateral total knee arthroplasty has com…
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Comparison of Postoperative Analgesic Effect of Intrathecal Clonidine and Fentanyl Added to Bupivacaine in Patients Undergoing Cesarean Section [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing postoperative analgesic effects of intrathecal clonidine versus fentanyl added to bupivacaine in cesare…