Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Wound Infiltration With Sodium Diclofenac vs Bupivacaine for Postoperative Pain Following Appendectomy [Phase 3]
A Phase 3 trial comparing wound infiltration with diclofenac sodium versus bupivacaine for postoperative pain after appendectomy has complet…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Lornoxicam Versus Etoricoxib in Postoperative Pain After Total Knee Arthroplasty [Phase 3]
A Phase 3 randomized trial comparing lornoxicam with etoricoxib for postoperative pain after total knee arthroplasty has completed.
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain [NA]
Completed clinical trial evaluating preventive use of a 5% lidocaine patch to control post-thoracotomy (postoperative) pain.
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations [NA]
A completed clinical trial comparing postoperative analgesic nerve block ropivacaine concentrations in total hip arthroplasty patients, with…
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients [Phase 3]
Phase 3 trial investigating the analgesic efficacy of repeated intravenous acetaminophen doses for postoperative pain in pediatric spine fus…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT [Phase 4]
Phase 4 clinical trial comparing caudal bupivacaine to intravenous morphine for time to first analgesic request in postoperative pain has co…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair [Phase 4]
Phase 4 clinical trial updating the impact of perioperative gabapentin on chronic groin pain after inguinal hernia repair.
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FDA approval · 2016-04-05FDA Approved: EXPAREL — Supplemental Application (Pacira Pharmaceuticals, Inc.)
The FDA approved a supplemental application for EXPAREL (bupivacaine) by Pacira Pharmaceuticals, expanding its labeling to include an additi…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Transdermal Fentanyl and Melatonin Patches for Postoperative Pain Relief
A completed clinical trial evaluated transdermal fentanyl combined with a melatonin patch for postoperative pain relief.
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Ultrasound-guided Selective Shoulder Block Versus Ultrasound-guided Interscalene Brachial Plexus Block, an RCT [NA]
An RCT comparing ultrasound-guided selective shoulder block to ultrasound-guided interscalene brachial plexus block for postoperative pain h…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia [NA]
A clinical trial comparing intraoperative methadone to morphine for postoperative pain control in tibia surgery was terminated, with results…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Parasternal Block and TENS for Cardiac Surgery [NA]
Completed clinical trial evaluating parasternal nerve block and TENS for managing postoperative pain after cardiac surgery.
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CLINICAL_TRIALS trial_result · 2016-03-30Clinical Trial Update: Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination [Phase 4]
Phase 4 trial comparing the analgesic effects of paracetamol, paracetamol–codeine, ibuprofen, and their combination in postoperative pain.
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy [NA]
Completed clinical trial comparing dexmedetomidine added to fentanyl-based IV PCA versus conventional thoracic epidural and IV PCA for posto…
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Effect of Oral Choline Supplementation on Postoperative Pain [Phase 4]
A Phase 4 clinical trial evaluated whether oral choline supplementation affects postoperative pain and inflammation, with results posted in …
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CLINICAL_TRIALS research · 2016-03-25Clinical Trial Update: A Randomized, Open Label, Prospective Study to Explore the Clinical Characteristics of Oral MNK155 and Norco 7.5mg/325 When Used for the Treatment of Moderate to Severe Post Operative Pain [Phase 3]
A randomized, open-label Phase 3 trial evaluating oral MNK155 in combination with Norco (hydrocodone/acetaminophen) for moderate to severe p…
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Ultrasound Guided Distal Peripheral Nerve Blocks and Postoperative Pain. [Phase 4]
Phase 4 clinical trial update on ultrasound-guided distal peripheral nerve blocks for postoperative pain. The trial has been completed and r…
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: Memantine and Postoperative Pain [Phase 4]
A Phase 4 clinical trial at Duke University evaluating memantine for postoperative pain was terminated, with results posted in March 2016.
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Prolonged Popliteal Fossa Nerve Blockade (Prolonged Pop) [Phase 1]
Phase 1 study evaluating prolonged popliteal fossa nerve blockade for postoperative pain; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Incidence of Urinary Retention in Patients Undergoing Unilateral Total Knee Arthroplasty- Comparison Between Continuous Epidural Analgesia and Single Shot Femoral Nerve Block- a Randomized Controlled Study (UriKANE) [NA]
A completed randomized controlled trial comparing continuous epidural analgesia versus single-shot femoral nerve block for unilateral total …
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183) [Phase 3]
Phase 3 trial evaluating two approved drugs for postoperative dental pain has completed.
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: Local Anesthetic Injection Into Both Angles of the Rectus Sheath Incision [EARLY_Phase 1]
Early-phase 1 trial evaluating local anesthetic injections at both angles of the rectus sheath incision to reduce postoperative pain after c…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: A Study of Efficacy and Safety of Qutenza in Patients With Post-operative Peripheral Neuropathic Pain
A completed clinical trial assessing the efficacy and safety of Qutenza (capsaicin patch) in patients with post-operative peripheral neuropa…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing intrathecal magnesium sulfate and midazolam with epidural ropivacaine for managing postoperative pain i…
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CLINICAL_TRIALS withdrawal · 2016-02-04Clinical Trial Update: Pharmacokinetics, Safety, and Efficacy of Intravenous Dosing of Buprenorphine in Pediatric Patients Who Require Opioid Analgesia for Acute Moderate to Severe Pain [Phase 3]
Phase 3 pediatric trial evaluating intravenous buprenorphine for acute postoperative pain was withdrawn.