Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: The Use of Intranasal Ketoralac for Pain Management (Sprix) [Phase 4]
Phase 4 trial update on intranasal ketorolac (Sprix) for postoperative pain management and urolithiasis, with the study terminated and resul…
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: Serratus Plane Block vs Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Unilateral Breast Surgery [Phase 4]
Phase 4 trial comparing serratus plane block to erector spinae plane block for postoperative analgesia after unilateral breast surgery.
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CLINICAL_TRIALS withdrawal · 2020-01-27Clinical Trial Update: Ideal Initial Bolus and Infusion Rate for Erector Spinae Plane Block Catheters [Phase 4]
Phase 4 trial on ideal initial bolus and infusion rate for erector spinae plane block catheters has been withdrawn.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Effects of Analgesics in Cesarean Section Elective [Phase 4]
Phase 4 clinical trial update assessing effects of analgesics in elective cesarean section; study completed.
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Acetaminophen vs Placebo in the Pre-operative Setting and Outcomes on Post-operative Pain, Nausea and Vomiting [Phase 3]
Phase 3 trial evaluating acetaminophen vs placebo in the pre-operative setting with outcomes on post-operative pain, nausea, and vomiting; t…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Intravenous Dexmedetomidine for Cesarean Section [Phase 4]
Phase 4 trial update on intravenous dexmedetomidine for cesarean section with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section [Phase 2]
Phase 2 trial assessing subcutaneous bupivacaine to reduce postoperative pain in cesarean section patients; study terminated with posted res…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Transmuscular Quadratus Lumborum Block for Total Laparoscopic Hysterectomy. [Phase 4]
A Phase 4 clinical trial evaluating transmuscular quadratus lumborum block for postoperative pain management in total laparoscopic hysterect…
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Dexamethasone as an Adjuvant to Ropivacaine for the Interscalene Brachial Plexus Block [Phase 4]
A Phase 4 clinical trial evaluating dexamethasone as an adjuvant to ropivacaine for interscalene brachial plexus block in postoperative pain…
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CLINICAL_TRIALS trial_result · 2019-12-26Clinical Trial Update: TAP Block in Laparoscopic Cholecystectomy. [Phase 2]
Phase 2 clinical trial update on TAP block for postoperative pain in laparoscopic cholecystectomy has been completed.
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial [Phase 4]
A Phase 4 randomized, placebo-controlled trial evaluating intravenous lidocaine for immediate post-operative pain, nausea, and vomiting afte…
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CLINICAL_TRIALS trial_result · 2019-12-02Clinical Trial Update: High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy [Phase 4]
A Phase 4 trial evaluating high vs low dose dexamethasone on postoperative complications after mastectomy; study completed with results post…
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterior Approach. [Phase 2]
Phase 2 clinical trial evaluating oral dexketoprofen/tramadol for acute postoperative pain after total hip replacement via direct anterior a…
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CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: Role of Intraoperative Beta Blocker for Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery [Phase 4]
Phase 4 clinical trial update examining the role of intraoperative beta blockers in morbidly obese patients undergoing laparoscopic bariatri…
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CLINICAL_TRIALS trial_result · 2019-11-14Clinical Trial Update: Dexmedetomidine Versus Magnesium Sulfate Infusion During Spinal Anesthesia [Phase 3]
Phase 3 clinical trial comparing dexmedetomidine vs magnesium sulfate infusion during spinal anesthesia for postoperative pain; study comple…
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Evaluation of Dexketoprofen in Total Knee Arthroplasty [Phase 2]
Phase 2 clinical trial evaluating dexketoprofen for postoperative analgesia after total knee arthroplasty.
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CLINICAL_TRIALS trial_result · 2019-11-06Clinical Trial Update: Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain [Phase 4]
A multicenter Phase 4 trial comparing intravenous and oral acetaminophen for acute moderate to severe postoperative pain was terminated; res…
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CLINICAL_TRIALS trial_result · 2019-11-05Clinical Trial Update: A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia [Phase 2, Phase 3]
A Phase II/III seamless trial evaluated paracetamol injection as an adjuvant to morphine-based postoperative analgesia; the study has comple…
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FDA approval · 2019-10-13FDA Approved: KETOROLAC TROMETHAMINE — Supplemental Application (Sandoz Inc)
FDA approved a supplemental application for ketorolac tromethamine filed by Sandoz Inc under an approved ANDA.
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction [Phase 3]
Phase 3 clinical trial evaluating Botulinum Toxin A (Botox) in tissue expander breast reconstruction has completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: Added Value of Systemic Lidocaine on Postoperative Pain, Opiate Use and Nausea After Knee Arthroscopy [Phase 4]
A Phase 4 clinical trial evaluated the added value of systemic lidocaine for postoperative pain, opioid use, and nausea after knee arthrosco…
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FDA approval · 2019-10-07FDA Approved: DSUVIA — Supplemental Application (AcelRx Pharmaceuticals, Inc.)
The FDA approved a supplemental application for DSUVIA (sufentanil) from AcelRx Pharmaceuticals, Inc.
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FDA label_change · 2019-10-07FDA Approved: MORPHINE SULFATE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA documents a supplemental application for Morphine Sulfate by Hikma Pharmaceuticals USA Inc., likely related to labeling changes for the …
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CLINICAL_TRIALS trial_result · 2019-10-04Clinical Trial Update: A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery [NA]
A completed randomized trial evaluated post-operative opioid quantities after urogynecologic surgery.
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CLINICAL_TRIALS trial_result · 2019-09-26Clinical Trial Update: Study of Oral Morphine Sulfate Administration in Pediatric Subjects [Phase 3]
Phase 3 clinical trial of oral morphine sulfate in pediatric patients for postoperative pain has completed.