Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Comparing Analgesic Efficacy of Systemic Lidocaine Against Placebo in General Anesthesia in Bariatric Surgery [Phase 3]
Phase 3 trial comparing systemic lidocaine to placebo for analgesic efficacy in bariatric surgery under general anesthesia has completed.
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain [NA]
A completed clinical trial evaluating postoperative peripheral nerve stimulation for managing post-amputation pain with results posted in 20…
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Bunionectomy Trial With GRT6005 [Phase 2]
Phase 2 clinical trial update for GRT6005 in post-operative pain management following bunionectomy; study status completed.
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CLINICAL_TRIALS trial_result · 2021-07-14Clinical Trial Update: Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision [Phase 4]
A Phase 4 clinical trial comparing surgical site infiltration of Exparel versus TAP block with Exparel in patients undergoing laparotomy via…
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Trial of Extended Release Bupivacaine for Pain Relief After Surgery [Phase 3]
Phase 3 trial of Extended Release Bupivacaine for post-operative pain completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: Maxigesic IV Phase 3 Bunionectomy Study [Phase 3]
Phase 3 trial results for Maxigesic IV in bunionectomy were completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: Comparison of Efficacy of Naproxen Versus Ibuprofen [Phase 4]
Clinical trial comparing naproxen to ibuprofen for postoperative pain; phase 4 completed.
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CLINICAL_TRIALS trial_result · 2021-07-02Clinical Trial Update: Phase 2 Herniorrhaphy Study for Opioid Elimination [Phase 2]
Phase 2 study evaluating HTX-011 (Zynrelef) for opioid-sparing postoperative pain control in herniorrhaphy; results posted.
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CLINICAL_TRIALS trial_result · 2021-07-01Clinical Trial Update: The Availability and Safety Study of Remimazolam Besylate for Injection on Sedation of ERAS Patients [Phase 3]
Phase 3 trial update on the availability and safety of remimazolam besylate for injection used in sedation of ERAS patients.
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CLINICAL_TRIALS trial_result · 2021-06-30Clinical Trial Update: High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain [Phase 4]
Phase 4 trial update evaluating high-dose steroids for reducing postoperative pain after hip arthroplasty; study completed.
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FDA approval · 2021-06-25FDA Approved: SUFENTANIL CITRATE — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for sufentanil citrate from Hospira, Inc., under ANDA074534.
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures [Phase 2]
A Phase 2 trial evaluating intrathecal paracetamol before spinal anesthesia with chloroprocaine for short knee procedures has completed with…
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CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section [Phase 2, Phase 3]
A dose-escalation study of dexamethasone aimed at increasing the duration of transversus abdominis plane block after cesarean section; study…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed [Phase 2]
Phase 2 trial completed evaluating optimal dose of caffeine in a naproxen caffeine combination tablet for pain after wisdom tooth extraction…
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CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery [Phase 2]
Phase 2 clinical trial evaluating SABER®-Bupivacaine for postoperative pain control after arthroscopic shoulder surgery; completed with resu…
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CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial [Phase 3]
Phase 3 trial update for minimally invasive thoracic surgery intercostal nerve block addressing thoracic diseases and postoperative pain; re…
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Duloxetine vs Pregabalin for Thoracotomy Pain [Phase 4]
Phase 4 clinical trial comparing duloxetine and pregabalin for postoperative pain management after thoracotomy.
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: Bupivacaine Effectiveness and Safety in SABER® Trial [Phase 3]
Phase 3 trial update on Bupivacaine in SABER study reports completed status with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery [Phase 2]
Phase 2 clinical trial update for SABER®-Bupivacaine in postoperative shoulder pain, reporting safety and effectiveness results.
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Undergoing Hysterectomy [Phase 2]
Phase 2 trial update assessing SABER-Bupivacaine for postoperative pain control in hysterectomy patients has completed and results were post…
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CLINICAL_TRIALS withdrawal · 2021-05-25Clinical Trial Update: Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain [Phase 4]
A Phase 4 trial evaluating preoperative gabapentin with TAP blocks to reduce postoperative pain was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Effects of Methylprednisolone Plus Ropivacaine Infiltration Before Wound Closure on Laminoplasty or Laminectomy [Phase 4]
Phase 4 clinical trial evaluating methylprednisolone plus ropivacaine infiltration before wound closure for postoperative pain in laminoplas…
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CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: Post C-Section Pain Control Using EXPAREL [Phase 4]
Phase 4 post-approval trial for EXPAREL in post-cesarean section pain control was withdrawn.
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FDA approval · 2021-05-12FDA Approved: ZYNRELEF — Original Application (Heron Therapeutics, Inc.)
FDA approved ZYNRELEF, a fixed-dose combination of bupivacaine and meloxicam, for postoperative analgesia. The product combines a local anes…
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CLINICAL_TRIALS trial_result · 2021-05-12Clinical Trial Update: Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System [NA]
Clinical trial update for electrical stimulation (SPRINT Beta System) addressing pain after total knee arthroplasty. Study completed with re…