Postoperative Ileus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition [NA]
Clinical trial update for SANICS II investigating autonomic nervous system stimulation via perioperative nutrition in colorectal surgery; st…
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: The Effect of Foeniculum Vulgare Ironing on Gastrointestinal Recovery After Colorectal Resection [Phase 2]
Phase 2 clinical trial evaluating Foeniculum vulgare (fennel) for gastrointestinal recovery after colorectal resection has completed.
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair [Phase 3]
Phase 3 trial update for intravenous MOA-728 in postoperative ileus after ventral hernia repair has completed with results posted.
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FDA label_change · 2019-05-08FDA Approved: BETHANECHOL CHLORIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental application for bethanechol chloride (generic) filed by Chartwell RX, LLC.
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: The Effect of Caffeine Ingestion in Prevention of Postoperative Ileus After Caesarean Section. [NA]
A completed clinical trial evaluated whether caffeine ingestion after cesarean section can prevent postoperative ileus.
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: Mouth Dissolving Mosapride Tables Enhance Post Cesarean Gut Recovery [Phase 3]
Phase 3 trial update on mouth-dissolving mosapride tables aimed at improving gut recovery after cesarean delivery.
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: Lidocaine Infusion in Radical Cystectomy [Phase 2]
Phase 2 clinical trial evaluating lidocaine infusion for postoperative ileus after radical cystectomy has completed.
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CLINICAL_TRIALS withdrawal · 2018-03-20Clinical Trial Update: RCT Gum Chewing on Bowel Function After Abdominal Surgery in Children [NA]
This is a withdrawn randomized trial evaluating whether gum chewing improves bowel function after abdominal surgery in children.
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CLINICAL_TRIALS other · 2017-11-01Clinical Trial Update: Tibial Nerve Stimulation and Postoperative Ileus [NA]
A clinical trial evaluating tibial nerve stimulation for postoperative ileus has completed.
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FDA approval · 2017-09-25FDA Approved: NEOSTIGMINE METHYLSULFATE — Original Application (Amphastar Pharmaceuticals, Inc.)
FDA approved Amphastar Pharmaceuticals' neostigmine methylsulfate as an original ANDA (ANDA209933) for indications including treatment of my…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus [Phase 3]
A Phase 3 study of alvimopan for managing opioid-induced postoperative bowel dysfunction and postoperative ileus has completed.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Nicotine Gum Recovery After Colorectal Surgery [Phase 4]
A Phase 4 trial evaluating nicotine gum for recovery after colorectal surgery was terminated, and results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-08-14Clinical Trial Update: The Effect of Gum Chewing on Bowel Function After Cesarean Section [NA]
The trial evaluated whether chewing gum improves bowel function after cesarean section. The study status is completed.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Effect of Continuous Thoracic Epidural Analgesia on Gut Motility Following Emergency Laparotomy
A completed clinical trial evaluated whether continuous thoracic epidural analgesia affects gut motility after emergency laparotomy. Sponsor…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus [Phase 2]
A Phase 2 clinical trial evaluated the safety and efficacy of ipamorelin for managing postoperative ileus; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery [Phase 4]
Phase 4 clinical trial update from the University of Illinois College of Medicine at Peoria evaluating multimodal, opioid-sparing perioperat…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Chewing Gums to Stimulate Intestinal Motility After Cesarean Section [NA]
A completed clinical trial evaluated chewing gum as a method to stimulate intestinal motility after cesarean delivery.
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Does Coffee Intake Reduce Postoperative Ileus After Elective Colorectal Surgery
This clinical trial examined whether daily coffee intake reduces postoperative ileus after elective colorectal surgery. The study has comple…
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Prucalopride for Postoperative Ileus in Patients Undergoing Gastrointestinal Surgery [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating prucalopride for postoperative ileus in patients undergoing …
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CLINICAL_TRIALS research · 2016-06-03Clinical Trial Update: Perioperative Use of a Selective COX2 Inhibitor in Patients Undergoing Elective Colorectal Surgery: the Effect on Post-operative Bowel Motility and Post-operative Pain [NA]
This clinical trial update concerns perioperative use of a selective COX-2 inhibitor in elective colorectal surgery to assess its effects on…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Influence of Coffee Intake on Postoperative Bowel Function After Comprehensive Staging Surgery for Gynecological Malignancies: A Randomized Controlled Trial. [NA]
A randomized controlled trial evaluated whether coffee intake improves postoperative bowel function after comprehensive staging surgery for …
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CLINICAL_TRIALS trial_result · 2016-02-01Clinical Trial Update: Role of Chewing Gum in Reducing Post Operative Ileus After Reversal of Ileostomy [NA]
Completed clinical trial evaluating whether chewing gum reduces postoperative ileus after reversal of ileostomy. The sponsor is Services Hos…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus [Phase 3]
Phase 3 study of alvimopan for opioid-induced postoperative bowel dysfunction and postoperative ileus has completed, per trial update.
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FDA approval · 2015-12-28FDA Approved: NEOSTIGMINE METHYLSULFATE — Original Application (Civica, Inc.)
FDA approved Civica, Inc.'s original application for Neostigmine Methylsulfate, a generic version of the drug.
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CLINICAL_TRIALS research · 2015-12-17Clinical Trial Update: Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery [Phase 4]
This update describes a Phase 4 clinical trial evaluating mosapride for reducing postoperative ileus in patients undergoing colorectal surge…