Postoperative Delirium
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CLINICAL_TRIALS trial_result · 2026-07-23Clinical Trial Results: Efficacy of Suvorexant on Post-operative Sleep Disturbance [Phase 4]
Phase 4 trial results evaluating suvorexant for postoperative sleep disturbance and delirium, with completed status and posted results.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
A Stanford-sponsored clinical trial is ongoing but not recruiting, aiming to develop a platform for precision anesthesia in elderly surgical…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Effect of Hyperoxia or Hypoxemia on the Incidence of Delirium in Patients After Cardiac Surgery
A completed clinical trial evaluated whether hyperoxia or hypoxemia affects the incidence of postoperative delirium in patients after cardia…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study [Phase 2]
Phase 2 study evaluating caffeine to prevent or reduce postoperative delirium and postoperative cognitive dysfunction after surgery; status …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Post Operative Cognitive Dysfunction After Breast Surgery
A University of Padova-sponsored clinical trial studying postoperative cognitive dysfunction after breast surgery is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Creatine and Perioperative Brain Health [NA]
Clinical trial update on creatine for perioperative brain health; not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES) [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial (MIDDIES) evaluating intranasal dexmedetomidine-induced sleep to prevent postoperative delirium after major…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery [NA]
A clinical trial protocol update evaluating an extended emergence strategy to reduce Post-Anesthesia Care Unit events after outpatient ortho…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Intranasal Insulin to Prevent Intensive Care Unit Delirium [Phase 2, Phase 3]
A clinical trial evaluating intranasal insulin to prevent postoperative delirium in ICU patients, currently listed as Phase 2/3 and not yet …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients [NA]
A Massachusetts General Hospital trial is evaluating digital sleep optimization to improve brain health outcomes in older surgical patients,…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence.
A clinical trial is recruiting to evaluate whether perioperative EEG variability is associated with the risk of postoperative delirium.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Impact of Sevoflurane Versus Propofol on Postoperative Delirium in Elderly Diabetic Patients Undergoing Non-Cardiac Surgery: a Multicenter, Randomized Controlled Trial [NA]
A multicenter randomized trial is comparing sevoflurane versus propofol to assess their effect on postoperative delirium in elderly patients…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium [Phase 3]
This entry reports an ongoing Phase 3 trial called SCOPE evaluating a Sleep, Cognition, and Pain Bundle versus ERAS-cardiac for postoperativ…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients [Phase 4]
Phase 4 trial evaluating esketamine for preventing delayed neurocognitive recovery in elderly patients after noncardiac surgery. The study f…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Prediction and Prevention of Postoperative Mortality and Morbidity [NA]
This ClinicalTrials.gov entry describes a study to predict and prevent postoperative mortality and morbidity in patients with dementia and p…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Correlation Between Preoperative Sleep and Postoperative Brain and Renal Dysfunction
An clinical trial investigating the relationship between preoperative sleep and postoperative brain and renal dysfunction, focusing on posto…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Depth of Anaesthesia and Long-term Survival: The Balanced Anaesthesia Follow-up Study
This clinical trial update describes a follow-up study evaluating whether depth of anesthesia during surgery is associated with long-term ou…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Sex-Dependent Risk of Postoperative Delirium and Mediating Effects of Family Visits
A clinical trial focusing on sex-dependent risk of postoperative delirium and how family visits may mediate this risk; the study is not yet …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Preoperative Distress and Postoperative Delirium in Elderly Patients Undergoing Major Orthopedic Surgery
This study investigates the relationship between preoperative distress and postoperative delirium in elderly patients undergoing major ortho…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium
A completed clinical trial evaluated whether serum S100B levels and S100B gene polymorphisms predict postoperative cognitive dysfunction and…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Value of the Time-Weighted Average (TWA) of Mean Arterial Pressure (MAP) and Cerebral Oximetry (rSO₂) as Predictors of Postoperative Tissue Perfusion Impairment in Patients Undergoing Cardiac Surgery
A clinical trial evaluating whether time-weighted MAP and cerebral oximetry predict postoperative tissue perfusion impairment in patients un…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Cerebral Oxygen Consumption Response to Increased Oxygen Supply and Postoperative Delirium in Older Surgical Patients
Sponsored by Seoul National University Bundang Hospital, the trial investigates how increasing oxygen supply affects cerebral oxygen consump…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Elderly Patients Undergoing Surgery During Perioperative Period
A ClinicalTrials.gov study from the Second Affiliated Hospital of Wenzhou Medical University is actively recruiting elderly patients to inve…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Effect of Low Tidal Volume Ventilation on Postoperative Delirium [NA]
A completed clinical trial investigated whether low tidal volume ventilation influences the development of postoperative delirium in patient…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Reducing Delirium After CABG Surgery With Early Activation and Sleep-Promoting Routines [NA]
This ongoing clinical trial in Singapore is testing whether early activation and sleep-promoting routines can reduce postoperative delirium …