Post-dural Puncture Headache
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: "Isometric Lower Limbs Exercises Affect on Cardiac Parameters and Headache in Patient After Spinal Anesthesia" [NA]
This clinical trial evaluates whether isometric lower-limb exercises affect cardiac parameters and headache after spinal anesthesia; the stu…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia [EARLY_Phase 1]
A Phase 1 trial in parturients undergoing elective cesarean section with spinal anesthesia is evaluating nebulized dexmedetomidine or lidoca…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Comparison of Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Prophylaxis of PDPH in Patients With History of PDPH. [Phase 2]
A Phase 2 trial comparing acetaminophen vs aminophylline and aminophylline with dexamethasone for prophylaxis of post-dural puncture headach…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache [NA]
A clinical trial evaluating theophylline, sumatriptan, and gabapentin for post-dural puncture headache is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: The Effect of Magnesium on Post-spinal Headaches
This clinical trial investigates whether magnesium can affect post-dural puncture headaches; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Sphenopalatine Ganglion Block for Post-Dural Puncture Headache [NA]
A completed clinical trial evaluated a sphenopalatine ganglion block for treating post-dural puncture headache, sponsored by ISSSTE Hospital…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients
This clinical trial investigates whether optic nerve sheath diameter can predict post-dural puncture headache in women undergoing cesarean s…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture [Phase 2]
A Phase 2 clinical trial evaluating neostigmine with glycopyrrolate for treating post-dural puncture headache is currently recruiting. The s…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Comparison of Post-Dural Puncture Headache After Spinal Anesthesia Using Median Versus Paramedian Approach [NA]
This clinical trial compares median versus paramedian spinal needle approaches to post-dural puncture headache after spinal anesthesia; the …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches [Phase 3]
Phase 3 clinical trial evaluating sphenopalatine block versus epidural blood patch for managing post-dural puncture headaches is currently r…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery
A planned clinical trial evaluating whether ultrasonographic optic nerve sheath diameter can predict post-dural puncture headache after spin…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Optic Nerve Sheath Diameter in Postspinal Headache
A completed clinical trial sponsored by Konya City Hospital evaluated optic nerve sheath diameter as a biomarker in post-dural puncture head…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery
Clinical trial investigating how altitude affects post-dural puncture headache after cesarean delivery; currently recruiting.
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch in Post Partum
A clinical trial investigating factors linked to developing chronic headaches in postpartum patients who received an autologous blood patch …
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CLINICAL_TRIALS withdrawal · 2025-08-15Clinical Trial Update: Caffeine Versus Placebo for Spinal Headaches [NA]
A clinical trial comparing caffeine to placebo for post-dural puncture headache has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE) [Phase 2]
A Phase 2 study evaluating the effectiveness and tolerability of tetracosactide (Synacthen) for post-dural puncture headaches was terminated…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients [NA]
A prospective study evaluating a modified lumbar puncture procedure to reduce post-dural puncture headaches in patients.
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Evaluation of Post-dural Puncture Headache in Female Patients Undergoing Obstetric and Non-obstetric Surgery
A clinical trial evaluating post-dural puncture headache in female patients undergoing obstetric and non-obstetric surgery is currently recr…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section [NA]
A completed clinical trial comparing nebulized dexmedetomidine to oral sumatriptan for the treatment of post-dural puncture headache after c…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial. [EARLY_Phase 1]
An early-phase randomized trial comparing nebulized neostigmine with atropine versus nebulized lignocaine for acute post-dural puncture head…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Pathophysiology and Treatment of Cerebrospinal Hypotension Exploration Study
An ongoing exploratory clinical trial at the Danish Headache Center studies the pathophysiology and treatment of cerebrospinal hypotension, …
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Establishment of a Predictive Model for Post-dural Puncture Headache
A clinical trial update describing the establishment of a predictive model for post-dural puncture headache following spinal/epidural anesth…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical Surgeries [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing prophylactic IV neostigmine plus atropine versus ketorolac for prevention of post-dural puncture headac…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: The Freiburg Registry on SpontanEous IntercrAnial Hypotension (SIH) & Post-duraL Puncture Headache (PDPH)
The Freiburg Registry is recruiting to study spontaneous intracranial hypotension and post-dural puncture headache related to cerebrospinal …
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: The Occurrence of Post Dural Puncture Headache After Epidural Blood Patch
A completed clinical trial reports the occurrence of post-dural puncture headache following an epidural blood patch.