Portal Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: CARPEUS : Effect of Carvedilol on the Portosystemic Gradient as Measured by Endoscopic Ultrasound [NA]
The CARPEUS trial update shows recruitment for evaluating carvedilol's effect on the portosystemic gradient in patients with cirrhosis-relat…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)
The IMPHROVE-D trial reports improvement of portal hypertension in patients with hepatitis D during viral suppression; the study is active b…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: LiveSMART Trial to Prevent Falls in Patients With Cirrhosis [Phase 3]
Phase 3 LiveSMART trial evaluating falls prevention in patients with cirrhosis has completed. The study enrolled patients with cirrhosis and…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: hepatomiR cACLD Study
The hepatomiR cACLD clinical trial, sponsored by Karl Landsteiner University of Health Sciences, is currently recruiting for chronic liver d…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors
A registered clinical trial from The Chinese University of Hong Kong is evaluating the safety of discontinuing non-selective beta-blockers i…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: A Digital Tongue Diagnosis Model for High- and Low-risk Esophagogastroduodenal Varices in Cirrhosis
This document provides a clinical trial update for a digital tongue diagnosis model intended to assess high- and low-risk esophagogastroduod…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: EUS-guided Portal Pressure Gradient (PPG) Measurement: a Potential Alternative to the Traditional HVPG [NA]
The document outlines a recruiting clinical trial evaluating endoscopic ultrasound-guided portal pressure gradient measurement as a potentia…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Portal Inflow Modulation Prior to Liver Transplantation in Patients With Increased Risk of Intraoperative Blood Loss [NA]
Clinical trial evaluating portal inflow modulation before liver transplantation in patients with liver cirrhosis and portal hypertension; cu…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: A Study to Predict Recompensation in Patients With Decompensated Cirrhosis Using Spleen Stiffness and Simple Blood Tests
This clinical trial aims to predict recompensation in patients with decompensated cirrhosis using spleen stiffness measurements and simple b…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients [NA]
A pilot trial evaluating the feasibility of using home blood pressure monitoring to optimize midodrine dosing in patients with decompensated…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Frequency of Portal Hypertension Among Patient With Cirrhotic Liver With Ultrasound
This clinical trial update describes a study assessing the frequency of portal hypertension in patients with liver cirrhosis. The study is c…
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CLINICAL_TRIALS other · 2025-06-22Clinical Trial Update: Non-selective Beta-blocker in Compensated Advanced Chronic Liver Disease [Phase 4]
Phase 4 clinical trial update for a non-selective beta-blocker in compensated advanced chronic liver disease. The study targets portal hyper…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) [Phase 2]
Phase 2 study evaluating two doses of Avenciguat in people with liver cirrhosis and portal hypertension has been terminated, with results po…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the Belly [Phase 2]
A Phase 2 trial evaluating Avenciguat in patients with liver cirrhosis and portal hypertension who had esophageal bleeding or ascites was te…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease
Completed clinical trial evaluating long-haul COVID-19 and vaccine immunogenicity in patients with liver disease.
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial [Phase 3]
Phase 3 multicenter double-blind trial assessing long-term carvedilol to prevent hepatic decompensation or death in asymptomatic Child-Pugh …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients [NA]
A clinical trial evaluating laparoscopic splenectomy with azygoportal disconnection to assess liver reserve function in patients with liver …
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury
A recruiting clinical trial at Nanfang Hospital, Southern Medical University, investigates outcomes for inpatients with chronic liver diseas…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Electromagnetic Positioning-Assisted Ultrasound Guidance in Transjugular Intrahepatic Portosystemic Shunt (TIPS) [NA]
This clinical trial investigates electromagnetic positioning-assisted ultrasound guidance to improve transjugular intrahepatic portosystemic…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients [Phase 2, Phase 3]
NEPH-ROSIS, a Phase 2/3 pilot trial for treating acute kidney injury in hospitalized cirrhosis patients, has been terminated.
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension
A clinical trial from Shanghai Zhongshan Hospital is recruiting to improve endoscopic and interventional strategies for gastroesophageal hem…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Effectiveness of Treatments for Cirrhosis With Varicose Veins
The document provides an update on the effectiveness of treatments for cirrhosis with varicose veins, focusing on esophageal variceal bleedi…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents [NA]
This clinical trial update compares large-volume paracentesis with early transjugular intrahepatic portosystemic shunt using Viatorr control…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) [Phase 2]
A Phase 2 study evaluating BI 685509 alone or with empagliflozin for liver cirrhosis due to viral hepatitis or non-alcoholic steatohepatitis…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Effects of Metformin on Hepatic Venous Pressure Gradient in Patients With Cirrhosis and Portal Hypertension [Phase 2]
Phase 2 clinical trial evaluating the effects of metformin on hepatic venous pressure gradient in patients with cirrhosis and portal hyperte…