Portal Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal [Phase 4]
Phase 4 clinical trial evaluating non-selective beta-blockers to prevent decompensation in cirrhosis with portal hypertension has completed.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Prevention of Esophageal Varices by Beta-Adrenergic Blockers [Phase 3]
Phase 3 trial evaluating whether beta-adrenergic blockers can prevent esophageal and gastric varices in patients with liver cirrhosis; the s…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C) [NA]
A completed clinical trial (SPLEEN-C) evaluating transient elastography to measure liver fibrosis and portal hypertension in patients with c…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS
This clinical trial update reports that changes in shear-wave elastography (SWE) after TIPS may help predict prognosis in patients with port…
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure [Phase 2]
Phase 2 trial of NCX-1000 in patients with portal hypertension showed preliminary efficacy signals and tolerability after repeated oral dosi…
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension [Phase 2]
Phase 2 study of IDN-6556 (emricasan) in patients with cirrhosis and portal hypertension completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Evaluation of Probiotics in the Treatment of Portal Hypertension [NA]
The trial update notes the completion of a study evaluating probiotics for portal hypertension in patients with liver cirrhosis, portal hype…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension [Phase 2]
Phase 2 trial of cobiprostone in portal hypertension was terminated; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal Hypertension
A completed clinical trial conducted in Egypt examined risk factors for variceal bleeding in patients with non-cirrhotic portal hypertension…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation [Phase 2]
Phase 2 trial evaluating sofosbuvir and ribavirin in adults with chronic hepatitis C and cirrhosis, including patients with portal hypertens…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: TIPS With 8- OR 10-mm Covered Stent for Preventing Variceal Rebleeding [NA]
A completed clinical trial evaluated using 8- or 10-mm covered stents for transjugular intrahepatic portosystemic shunt (TIPS) to prevent va…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension [Phase 2]
Phase 2 exploratory haemodynamic study in patients with compensated cirrhosis and portal hypertension. Results were posted in January 2016.
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices [NA]
A clinical trial comparing Cyanoacrylate+Lipiodol versus Cyanoacrylate+Lauromacrogol for gastric varices has completed.
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis [Phase 4]
This update notes the completion of a Phase 4 clinical trial evaluating taurine's effects on portal hemodynamics in patients with advanced l…
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding [Phase 3]
A Phase 3 clinical trial evaluates whether adding a statin to standard therapy reduces recurrent hemorrhage in patients with cirrhosis and p…
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope [Phase 3]
Phase 3 trial comparing two endoscopic methods to stop hematemesis in patients with portal hypertension; the study has completed.
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Evaluation of Efficacy and Safety of Somatostatin Used as Inflow Modulator in Liver Transplantation. [Phase 1]
A completed Phase 1 clinical trial evaluating somatostatin as an inflow modulator to assess safety and efficacy in liver transplantation for…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices [NA]
This clinical trial update investigates predictive factors and outcomes of esophageal ulcers after endoscopic treatment of esophageal varice…
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Probiotics for Liver Cirrhosis With Portal Hypertension [NA]
This ClinicalTrials.gov update notes the completed study of probiotics for patients with liver cirrhosis and portal hypertension, with resul…
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CLINICAL_TRIALS trial_result · 2014-06-03Clinical Trial Update: Early TIPS for Ascites Study [NA]
This item reports the termination and results of an early TIPS trial for ascites in patients with liver cirrhosis and portal hypertension.
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Simvastatin Effect on Portal Hypertension [Phase 3]
Phase 3 trial evaluating simvastatin for portal hypertension has completed.
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CLINICAL_TRIALS trial_result · 2013-10-07Clinical Trial Update: Randomized Controlled Trial to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patients With Liver Cirrhosis and Portal Hypertension [Phase 2, Phase 3]
A randomized controlled trial evaluating the effects of sapropterin on hepatic and systemic hemodynamics in patients with liver cirrhosis an…
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CLINICAL_TRIALS trial_result · 2013-09-23Clinical Trial Update: Quality of Life and Nutritional Improvements in Cirrhotic Patients [Phase 4]
Phase 4 clinical trial assessing quality of life and nutritional improvements in patients with liver cirrhosis, hepatic encephalopathy, and …
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CLINICAL_TRIALS trial_result · 2013-08-29Clinical Trial Update: Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery [NA]
A completed clinical trial evaluating endoscopy versus surgery for schistosomal portal hypertension and related upper gastrointestinal bleed…
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CLINICAL_TRIALS trial_result · 2012-12-19Clinical Trial Update: The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPS [Phase 2, Phase 3]
This clinical trial update reports on the effectiveness of L-ornithine-L-aspartate (LOLA) for reducing plasma ammonia in cirrhotic patients …