Portal Hypertension
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Electromagnetic Positioning-Assisted Ultrasound Guidance in Transjugular Intrahepatic Portosystemic Shunt (TIPS) [NA]
This clinical trial investigates electromagnetic positioning-assisted ultrasound guidance to improve transjugular intrahepatic portosystemic…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension
A clinical trial from Shanghai Zhongshan Hospital is recruiting to improve endoscopic and interventional strategies for gastroesophageal hem…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents [NA]
This clinical trial update compares large-volume paracentesis with early transjugular intrahepatic portosystemic shunt using Viatorr control…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Effects of Metformin on Hepatic Venous Pressure Gradient in Patients With Cirrhosis and Portal Hypertension [Phase 2]
Phase 2 clinical trial evaluating the effects of metformin on hepatic venous pressure gradient in patients with cirrhosis and portal hyperte…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Early TIPS in Patients With Liver Cirrhosis and Ascites [NA]
A clinical trial update indicating that early TIPS (transjugular intrahepatic portosystemic shunt) is being explored in patients with liver …
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Clinical Study on the Selection of Endoscopic Varicose Disconnection Strategy Based on Natural Portal Shunt with Portal Hypertension [NA]
This clinical trial update describes a study evaluating endoscopic variceal disconnection strategies based on natural portal shunt in portal…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Direct Portal Pressure Measurement Via Endoscopic Ultrasound in Advanced Chronic Liver Disease (EVADIPP)
A clinical trial recruiting to evaluate direct portal pressure measurement via endoscopic ultrasound in patients with advanced chronic liver…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: The Instant Efficacy and Safety of Alverine in Decreasing Portal Hypertension: an Exploratory Pilot Study [Phase 2]
This document provides an update on an ongoing Phase 2 exploratory pilot trial evaluating alverine for reducing portal hypertension.
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: AI-guided TIPS Procedure [NA]
A clinical trial examining AI-guided transjugular intrahepatic portosystemic shunt (TIPS) for portal hypertension related to cirrhosis is no…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension
Clinical trial update describing a study of colonic polypectomy in patients with liver cirrhosis and portal hypertension; the trial is activ…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: SHAPE of Portal Hypertension in Children [Phase 2]
Phase 2 clinical trial update for the SHAPE study investigating portal hypertension in pediatric patients; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose [Phase 4]
Phase 4 clinical trial update evaluating prophylaxis of post-TIPS hepatic encephalopathy using rifaximin and lactulose is currently recruiti…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic With Advanced HCC
This clinical trial investigates whether measurements of liver and spleen stiffness can predict the presence of esophageal varices in patien…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant [Phase 2]
A Phase 2 clinical trial evaluating the combination of durvalumab and tremelimumab for hepatocellular carcinoma in patients listed for liver…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Carvedilol and Alverine in Portal Hypertension [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating carvedilol and alverine for portal hypertension is currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Von Willebrand Factor Levels in Patients With Liver Cirrhosis and Portal Hypertension
This clinical trial update indicates that the study assessing von Willebrand Factor levels in patients with liver cirrhosis and portal hyper…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: Austrian Registry on Transjugular Intrahepatic Portosystemic Shunts
Austrian registry study focused on transjugular intrahepatic portosystemic shunts (TIPS) for portal hypertension; recruitment is currently o…
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CLINICAL_TRIALS research · 2024-09-26Clinical Trial Update: Albumin Bilirubin Index as a Predictor of Outcome of Variceal Bleeding
This study is evaluating whether the albumin–bilirubin index can predict outcomes in patients with variceal bleeding; recruitment is ongoing…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Protocol for Muscle Attenuation Cut-offs in Cirrhosis
A completed clinical trial protocol outlining muscle attenuation cut-offs for assessing myosteatosis and sarcopenia in cirrhosis, including …
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension [Phase 2, Phase 3]
Clinical trial update indicates evaluation of alverine for cirrhotic portal hypertension in Phase 2 and Phase 3, with the study currently no…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis [Phase 2, Phase 3]
Alverine is being evaluated in Phase 2 and Phase 3 trials for portal hypertension in patients with liver cirrhosis, and the study is not yet…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease. [Phase 3]
Phase 3 trial update announcing a study to evaluate zinc supplementation for improving prognosis in patients with compensated advanced chron…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Freiburg TIPS Registry
Clinical trial update for Freiburg's TIPS Registry showing ongoing recruitment for a registry study of portal hypertension-related condition…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India
An Indian clinical trial investigating the clinical diagnosis and pathology of porto-sinusoidal vascular disease and related liver condition…
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CLINICAL_TRIALS research · 2019-05-14Clinical Trial Update: Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension [Phase 2, Phase 3]
A clinical trial update evaluating propranolol, carvedilol, and rosuvastatin for prevention of variceal bleeding in cirrhotic portal hyperte…