Polypoidal Choroidal Vasculopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Efficacy and Durability of a Personalized Treat-and-extend Regimen of Faricimab for Treatment-naive Polypoidal Choroidal Vasculopathy [Phase 3]
A Phase 3 clinical trial update reports on evaluating a personalized treat-and-extend regimen of Faricimab for treatment-naive polypoidal ch…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Intravitreal (IVT) Injection of ABI-110 (AAV2.N54-VEGF Trap) in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (wAMD), Including Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) [Phase 1, Phase 2]
This document describes an ongoing Phase 1/2 clinical trial evaluating the safety, tolerability, and preliminary efficacy of intravitreal AB…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Study to Investigate the Efficacy, Safety and Durability of Faricimab in Caucasian Patients With Polypoidal Choroidal Vasculopathy (MONDEGO) [Phase 4]
Phase 4 clinical trial update investigating the efficacy, safety and durability of faricimab in Caucasian patients with polypoidal choroidal…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Prospective Trial of the Efficacy and Safety of a Personalized Regimen of High-dose Aflibercept 8mg on Treatment-naive Polypoidal Choroidal Vasculopathy: the PALLAS Trial [Phase 3]
Phase 3 trial evaluating a personalized high-dose aflibercept (8 mg) regimen for treatment-naive polypoidal choroidal vasculopathy; currentl…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: A Prospective, Multicenter, Open-label, Randomized Clinical Trial to Evaluate the Efficacy, Durability, and Safety of Aflibercept 8mg in Different Treatment Regimens in Chinese Patients With Polypoidal Choroidal Vasculopathy (PCV) [Phase 4]
Phase 4 clinical trial evaluating different regimens of aflibercept 8 mg in Chinese patients with polypoidal choroidal vasculopathy, assessi…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Long-term Outcomes, Recurrence Rates, and Treatment Needs in Polypoidal Choroidal Vasculopathy (PCV)
This completed clinical trial update reports on long-term outcomes, recurrence rates, and treatment needs in polypoidal choroidal vasculopat…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment [NA]
Clinical trial update comparing intravitreal aflibercept monotherapy to aflibercept with reduced fluence PDT for Polypoidal Choroidal Vascul…
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: Adjunct Episcleral Brachytherapy for PCV [Phase 3]
Phase 3 clinical trial update for adjunct episcleral brachytherapy in polypoidal choroidal vasculopathy and age-related macular degeneration…
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CLINICAL_TRIALS trial_result · 2022-12-12Clinical Trial Update: Safety Study of 2.0mg Lucentis to Treat Polypoidal Choroidal Vasculopathy [Phase 1, Phase 2]
A safety-focused clinical trial update for 2.0 mg Lucentis in polypoidal choroidal vasculopathy (Phase 1/2) with completed status and result…
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CLINICAL_TRIALS trial_result · 2021-08-18Clinical Trial Update: An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy [Phase 4]
Phase 4 open-label study assessing aflibercept monotherapy for polypoidal choroidal vasculopathy, completed with posted results in 2021.
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CLINICAL_TRIALS research · 2020-10-23Clinical Trial Update: Intravitreal Aflibercept for Treatment of Polypoidal Choroidal Vasculopathy (PCV) [Phase 4]
Phase 4 trial updating intravitreal aflibercept for treatment of symptomatic macular polypoidal choroidal vasculopathy (PCV) completed.
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CLINICAL_TRIALS trial_result · 2020-05-08Clinical Trial Update: Efficacy and Safety of Two Regimens of Anti-VEGF Therapy in Chinese Patients With Polypoidal Choroidal Vasculopathy [Phase 4]
Phase 4 clinical trial update evaluating two regimens of anti-VEGF therapy for polypoidal choroidal vasculopathy in Chinese patients, focusi…
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CLINICAL_TRIALS trial_result · 2020-01-10Clinical Trial Update: Randomized, Double-masked, Sham-controlled Phase 4 Study, Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic Therapy in Patients With Polypoidal Choroidal Vasculopathy [Phase 4]
Phase 4 randomized trial comparing intravitreal aflibercept monotherapy to aflibercept with adjunctive photodynamic therapy in polypoidal ch…
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: Intraocular Cytokine in Recurrence of Polypoidal Choroidal Vasculopathy [Phase 4]
A Phase 4 clinical trial update investigating intraocular cytokine therapy for recurrence of polypoidal choroidal vasculopathy, associated w…
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy [Phase 2, Phase 3]
A phase 2/3 clinical trial investigating double-dose ranibizumab for polypoidal choroidal vasculopathy was terminated.
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CLINICAL_TRIALS trial_result · 2019-07-19Clinical Trial Update: Initial Versus Delayed PDT Combination With Conbercept in PCV [Phase 4]
Phase 4 trial comparing initial versus delayed photodynamic therapy (PDT) in combination with conbercept for polypoidal choroidal vasculopat…
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CLINICAL_TRIALS trial_result · 2019-06-07Clinical Trial Update: Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT) [Phase 4]
Phase 4 trial comparing ranibizumab monotherapy versus ranibizumab combined with verteporfin photodynamic therapy for symptomatic macular po…
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CLINICAL_TRIALS trial_result · 2018-11-30Clinical Trial Update: Intravitreal Ranibizumab and TA Combination Therapy vs. Ranibizumab Monotherapy in Polypoidal Choroidal Vasculopathy [Phase 4]
Phase 4 trial comparing intravitreal ranibizumab with triamcinolone acetonide (TA) combination therapy versus ranibizumab alone for polypoid…
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Efficacy and Safety of Intravitreal Vascular Endothelial Growth Factor Trap-eye in Patients With Polyploidal Choroidal Vasculopathy [Phase 4]
A Phase 4 trial assessing the efficacy and safety of an intravitreal VEGF trap-eye in patients with polyploidal choroidal vasculopathy (PCV)…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Comparison of PDT, Intravitreal Ranibizumab and Combination for Polypoidal Choroidal Vasculopathy Under 1+PRN Regimen [NA]
Completed clinical trial comparing photodynamic therapy (verteporfin), intravitreal ranibizumab, and their combination for polypoidal choroi…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Assessment of Visual Acuity in Patients With Polypoidal Choroidal Vasculopathy and Aflibercept Treatment [NA]
This trial update reports on visual acuity outcomes in patients with polypoidal choroidal vasculopathy treated with aflibercept, in a comple…
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Investigator Sponsored Trial of Polypoidal Choroidal Vasculopathy (PCV) Evaluation Assessing High-Dose Ranibizumab Prospectively (PEARL2) [Phase 1, Phase 2]
An investigator-sponsored Phase 1/2 trial evaluating high-dose ranibizumab for polypoidal choroidal vasculopathy has completed. Results were…
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: Phase IV Clinical Trial (STAR Study) Extension Study of Conbercept Ophthalmic Injection for Treatment of Polypoid Choroidal Vasculopathy [Phase 4]
Phase IV extension study (STAR Study) of Conbercept ophthalmic injection for polypoidal choroidal vasculopathy is underway, with the current…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: The Efficacy Assessment of Intravitreal Injection of Conbercept in Patients With Polypoidal Choroidal Vasculopathy (PCV) [Phase 4]
Phase 4 clinical trial evaluating the efficacy of intravitreal Conbercept for polypoidal choroidal vasculopathy.
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CLINICAL_TRIALS research · 2017-04-25Clinical Trial Update: Pharmacogenomic Study on Anti-VEGF Medicine in Treatment of Macular Neovascular Diseases
This clinical trial update describes a pharmacogenomic study of the anti-VEGF drug Conbercept for macular neovascular diseases, including ag…