Pleural Effusion
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases
This clinical trial investigates validating the Lung Sliding Index (LSI) to differentiate pulmonary diseases and assess its clinical utility…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Confocal Laser Endomicroscopy Assisted Ultrasound Guided Pleural Biopsy [NA]
This clinical trial update notes a not-yet-recruiting study evaluating confocal laser endomicroscopy-assisted ultrasound-guided pleural biop…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion
Completed clinical trial examining neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios in exudative pleural effusion.
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Evaluating the Efficacy and Safety of Saline Irrigation as an Add-On Therapy for Retained Pleural Infections [LYTICS +] [Phase 2]
Phase 2 clinical trial assessing saline irrigation as an add-on treatment for retained pleural infections; study is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG [NA]
A clinical trial called ARMSTRONG is evaluating air entraintment versus standard treatment in non-expandable lung conditions and is currentl…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. [NA]
Clinical trial assessing first local anesthesia thoracoscopy for diagnosing pleural effusion in patients with suspected malignant lung disea…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Drainage Of Pleural Effusions in the Intensive Care Unit (DOPE-ICU) - Feasibility Trial [NA]
A feasibility study evaluating drainage of pleural effusions in ICU patients, with recruitment currently ongoing.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Improvement to Perform Thoracocentesis After a Specific Training in Medical Students With the Supervised Use of an Augmented Reality Simulator
A clinical trial evaluating whether a specific training program using an augmented reality simulator improves medical students' ability to p…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Effectiveness and Safety of Sodium Bicarbonate Pleural Lavage in the Treatment of Complex Pleural Effusion [NA]
A clinical trial is recruiting to test the effectiveness and safety of sodium bicarbonate lavage for complex pleural effusion and empyema.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Thoracentesis to Alleviate Cardiac Pleural Effusion [NA]
A clinical trial evaluating thoracentesis to relieve cardiac pleural effusion in patients with heart failure has completed.
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis [Phase 4]
Phase 4 trial evaluating whether intrapleural fibrinolytic therapy can enhance the effectiveness of chemical pleurodesis in pleural effusion…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Strategy for Prompt and Effective Thoracentesis in the Emergency Department [NA]
A University of Aarhus-sponsored clinical trial aims to develop a prompt and effective thoracentesis strategy for emergency department patie…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Indwelling Pleural Catheter for Trapped Lung [NA]
Clinical trial NCT03550027 evaluating an indwelling pleural catheter for trapped lung has completed.
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
Clinical trial registry entry for the CENTRE study assessing the diagnostic performance of pleural fluid NT-proBNP compared with other crite…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Efficacy of 20% Human Albumin in Reducing Pleural Effusion After Cardiopulmonary Bypass [Phase 4]
Phase 4 trial evaluating whether 20% human albumin reduces pleural effusion after cardiopulmonary bypass; the study has completed.
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Medical Thoracoscopy With Flexible Bronchoscopy Versus Semi-Rigid Pleuroscope in Pleural Effusion (FLEXPLEUR)
The FLEXPLEUR trial comparing medical thoracoscopy with flexible bronchoscopy versus semi-rigid pleuroscopy for pleural effusion has complet…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Use of Vasopressin Following the Fontan Operation [Phase 2, Phase 3]
A Phase 2/Phase 3 trial assessed vasopressin after the Fontan operation to treat pleural effusions in patients with single-ventricular conge…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: GRAvity- Versus Wall Suction-drIven Large Volume Thoracentesis: a RAndomized Controlled Study (GRAWITAS Study) [NA]
Completed randomized controlled trial comparing gravity-driven versus wall suction-driven large-volume thoracentesis (GRAWITAS).
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Chest Drain Insertion Assisted by Virtual Reality [NA]
A clinical trial evaluating chest drain insertion assisted by virtual reality is not yet recruiting; it targets spontaneous pneumothorax (pr…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Image-Guided Pleural Needle Biopsy in Pleural Diseases [NA]
A completed clinical trial evaluating image-guided pleural needle biopsy techniques for pleural diseases conducted by Eskisehir Osmangazi Un…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: The Oxford Pleural Infection Endotyping Study
The Oxford Pleural Infection Endotyping Study has completed. The study investigates endotypes in pleural infection and related pleural disea…
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Persistent Pleural Effusion Treatment Following Cardiothoracic Surgery by Platelet-Fibrin Glue [Phase 2]
Phase 2 clinical trial evaluating the use of platelet-fibrin glue to treat persistent pleural effusion after cardiothoracic surgery has comp…
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CLINICAL_TRIALS research · 2024-03-06Clinical Trial Update: Active Clearance of Chest Tubes After Cardiac Surgery: A Prospective Randomized Controlled Study [NA]
A completed randomized trial evaluating active clearance of chest tubes after cardiac surgery; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis [Phase 4]
Phase 4 trial update evaluating topical lidocaine/prilocaine for pain management during pleurocentesis in pleural effusion.
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CLINICAL_TRIALS trial_result · 2023-03-30Clinical Trial Update: A Study to Evaluate LTI-01 in Patients With Infected, Non-draining Pleural Effusions [Phase 2]
Phase 2 study evaluating LTI-01 in patients with infected, non-draining pleural effusions has completed.