Pheochromocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Correlation Between Preoperative Images of PPGL and Intraoperative Hemodynamics
This clinical trial update analyzes the relationship between preoperative imaging of pheochromocytoma and paraganglioma (PPGL) and intraoper…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Study Of Sunitinib In Patients With Recurrent Paraganglioma/Pheochromocytoma [Phase 2]
Phase 2 trial evaluating Sunitinib in patients with recurrent paraganglioma and pheochromocytoma; the study is completed and results have be…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Phenoxybenzamine Versus Doxazosin in PCC Patients [Phase 4]
A Phase 4 trial comparing phenoxybenzamine to doxazosin in pheochromocytoma patients has completed.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of everolimus and vatalanib in patients with advanced solid tumors, including several neuroendocrin…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Metanephrines in Obstructive Sleep Apnoea
This clinical trial update reports a completed study investigating metanephrines in obstructive sleep apnea. The trial is sponsored by Chang…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: "Receptor Radionuclide Therapy With 177Lu-DOTATOC [Phase 2]
A Phase 2 trial evaluating receptor radionuclide therapy with 177Lu-DOTATOC for neuroendocrine tumors, including paraganglioma and pheochrom…
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
Clinical study from Universidad Nacional Autónoma de México exploring genetic factors underlying neuroendocrine neoplasms. The trial is curr…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma
This document outlines an expanded access/compassionate use protocol for 131I-MIBG therapy. It targets patients with refractory neuroblastom…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic [Phase 2]
Phase 2 study of pembrolizumab in patients with rare, unresectable or metastatic solid tumors; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: The Efficacy and Safety of Anlotinib in Patients With Metastatic Pheochromocytoma or Paraganglioma [Phase 2]
Phase 2 trial update showing efficacy and safety data for anlotinib in patients with metastatic pheochromocytoma or paraganglioma.
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Side-specific Factors for Intraoperative Hemodynamic Instability in Pheochromocytoma
Completed clinical trial investigating side-specific factors associated with intraoperative hemodynamic instability in pheochromocytoma.
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: The Incidence and Outcomes of Metabolically Active Brown Adipose Tissue (aBAT) in Patients With Pheochromocytoma or Paraganglioma (PPGLs)
This clinical trial, sponsored by King's College Hospital NHS Trust, studies the incidence and outcomes of metabolically active brown adipos…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers
A clinical trial update describing a study on environmental exposures and tumor risk in SDHx mutation carriers; the trial is not yet recruit…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Infrared Thermography Associated With Cutaneous Microcirculation for Detection of Brown-adipose Tissue (MICROBAT) [NA]
The MICROBAT trial investigating infrared thermography for detection of brown adipose tissue was terminated, involving patients with pheochr…
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease
This clinical trial update describes a completed University Medical Center Groningen study on visualizing VEGF-producing lesions associated …
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CLINICAL_TRIALS trial_result · 2023-11-20Clinical Trial Update: Preoperative Alpha Blockade for Pheochromocytoma [Phase 3]
Phase 3 trial evaluating preoperative alpha blockade for pheochromocytoma and paraganglioma has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-06-02Clinical Trial Update: The Efficacy and Safety of Penpulimab in the Treatment of Metastatic PPGL Patients Who Fail to Other Systemic Treatment [Phase 2]
Phase 2 clinical trial update evaluating penpulimab for metastatic pheochromocytoma/paraganglioma after failure of prior systemic treatments…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: A Study on the Safety and Effectiveness of Temozolomide for Neoadjuvant Treatment of PPGL [Phase 2]
Phase 2 study evaluating temozolomide as neoadjuvant therapy for pheochromocytoma and paraganglioma.
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: A Study on the Safety and Effectiveness of Anlotinib for Neoadjuvant Treatment of PPGL [Phase 2]
Phase 2 trial update evaluating safety and effectiveness of anlotinib as neoadjuvant therapy for pheochromocytoma and paraganglioma.
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CLINICAL_TRIALS trial_result · 2023-05-15Clinical Trial Update: The Efficacy and Safety of Temozolomide in Patients With MPPGL [Phase 2]
Phase 2 trial evaluating temozolomide for malignant pheochromocytoma and paraganglioma has completed.
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FDA approval · 2023-05-08FDA Approved: PHENOXYBENZAMINE HYDROCHLORIDE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for phenoxybenzamine hydrochloride manufactured by Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: First International Randomized Study in Malignant Progressive Pheochromocytoma and Paraganglioma [Phase 2]
A Phase 2 randomized international trial in malignant progressive pheochromocytoma and paraganglioma has completed.
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FDA approval · 2022-07-19FDA Approved: PHENOXYBENZAMINE HYDROCHLORIDE — Original Application (Novitium Pharma LLC)
FDA approved the original ANDA for phenoxybenzamine hydrochloride (generic) from Novitium Pharma LLC. The product is now available as a gene…
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CLINICAL_TRIALS trial_result · 2021-11-24Clinical Trial Update: A Prospective Phase II Efficacy and Safety Study of Anlotinib in Metastatic or Locally Advanced Pheochromocytoma/ Paraganglioma : Open-label Single-arm, Exploratory Trial [Phase 2]
Phase II open-label single-arm study evaluating efficacy and safety of anlotinib in advanced or metastatic pheochromocytoma/paraganglioma.
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CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: the Effect of Dexmedetomidine and Magnesium Sulfate in Open Resection of Pheochromocytoma [Phase 2]
Phase 2 trial evaluating dexmedetomidine and magnesium sulfate in open resection of pheochromocytoma has completed.