Phenylketonuria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: Testing of Four Home Phenylalanine Monitoring Prototype Devices
A completed clinical study evaluated four prototype devices for at-home phenylalanine monitoring in people with phenylketonuria.
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: The Effect of Supplemental Docosahexaenoic Acid (DHA) on Neurocognitive Outcomes in Teen and Adult Women With Phenylketonuria(PKU) [NA]
A completed clinical trial investigated whether supplemental docosahexaenoic acid (DHA) affects neurocognitive outcomes in teen and adult wo…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Bone Mineral Density in Adults With Hyperphenylalaninemia on Kuvan Therapy [NA]
This clinical trial update reports bone mineral density changes in adults with hyperphenylalaninemia treated with Kuvan. The study (NCT01541…
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CLINICAL_TRIALS trial_result · 2015-06-19Clinical Trial Update: The Brain, Neurological Features and Neuropsychological Functioning in Adults With Phenylketonuria: A Pilot Study [NA]
This clinical trial update reports results from a pilot study evaluating brain structure, neurological features, and neuropsychological func…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Bone Mineral Density in Adults With Hyperphenylalaninemia
This clinical trial update assesses bone mineral density in adults with hyperphenylalaninemia (phenylketonuria). The update summarizes the b…
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy [NA]
This clinical trial update reports FDG-PET imaging findings in patients with phenylketonuria before and after treatment with Kuvan (sapropte…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Moderate Intensity Exercise and Phenylketonuria [NA]
A clinical trial investigating moderate-intensity exercise in phenylketonuria has been terminated.
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CLINICAL_TRIALS trial_result · 2014-08-28Clinical Trial Update: Phenylketonuria, Oxidative Stress, and BH4 [Phase 2]
A Phase 2 trial evaluating tetrahydrobiopterin (BH4) in phenylketonuria was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Nutritional and Neurotransmitter Changes in PKU Subjects on BH4
A completed Emory University clinical trial studied nutritional and neurotransmitter changes in people with phenylketonuria treated with tet…
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: The Early History of Universal Screening for Metabolic Disorders
This completed clinical trial update from the University of Miami provides historical context on the early universal screening programs for …
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria [Phase 3]
A Phase 3 open-label study evaluating the response and safety of Kuvan (sapropterin dihydrochloride) in subjects with Phenylketonuria has co…
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CLINICAL_TRIALS trial_result · 2013-12-05Clinical Trial Update: Behavioral Effects of Kuvan in Children With Mild Phenylketonuria
A clinical trial evaluating the behavioral effects of Kuvan (sapropterin dihydrochloride) in children with mild phenylketonuria has been ter…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Follow-up of Adult Phenylketonuria (PKU) Patients
This clinical trial update reports the completion of follow-up in adult phenylketonuria (PKU) patients. The snippet does not provide detaile…
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CLINICAL_TRIALS trial_result · 2013-08-01Clinical Trial Update: Response to Kuvan® in Subjects With Phenylketonuria (PKU) in a 4 Weeks Testing Period [Phase 4]
Phase 4 trial update examining response to Kuvan (sapropterin dihydrochloride) in subjects with phenylketonuria over a 4-week testing period…
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: Study of Phenoptin in Subjects With Phenylketonuria Who Participated in Protocols PKU-004 or PKU-006 [Phase 3]
A Phase 3 trial of Phenoptin in phenylketonuria patients who participated in PKU-004 or PKU-006 has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2009-08-20Clinical Trial Update: A Phase 3, Multicenter, Open-Label Extension Study of Phenoptin in Subjects With PKU Who Have Elevated Phenylalanine Levels [Phase 3]
This update reports the completion of a Phase 3 multicenter open-label extension trial of Phenoptin in individuals with phenylketonuria and …
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CLINICAL_TRIALS trial_result · 2009-07-09Clinical Trial Update: Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet [Phase 3]
Phase 3 study evaluating Phenoptin to increase phenylalanine tolerance in children with phenylketonuria on a restricted diet has completed, …
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CLINICAL_TRIALS trial_result · 2009-04-16Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Phenoptin™ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels [Phase 3]
Phase 3 trial evaluating safety and efficacy of Phenoptin in individuals with phenylketonuria completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2007-09-20Clinical Trial Update: Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety [Phase 2, Phase 3]
A terminated Phase 2/3 trial evaluated long-term tetrahydrobiopterin treatment in children with phenylketonuria to assess phenylalanine tole…
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CLINICAL_TRIALS trial_result · 2007-04-09Clinical Trial Update: Study to Evaluate the Response to and Safety of an 8-Day Course of Phenoptin™ Treatment in Subjects With Phenylketonuria [Phase 2]
Phase 2 trial evaluating the response to and safety of an 8-day course of Phenoptin for phenylketonuria has completed.