Peripheral T-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Linperlisib Combined With Chidamide in Patients With PTCL [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of linperlisib with chidamide in patients with peripheral T-cell lymphoma is currently…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Ro Plus CHOEP as First Line Treatment Before HSCT in Young Patients With Nodal Peripheral T-cell Lymphomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial (NCT02223208) evaluates Ro plus CHOEP as first-line therapy before hematopoietic stem cell transplantation in you…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: BrEto-TCL - Defining the Role of Brentuximab and Etoposide for Optimizing First-line Therapy of T-cell Lymphomas [Phase 3]
Phase 3 trial updating the role of Brentuximab plus etoposide as first-line therapy for peripheral T-cell lymphoma; study is currently enrol…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: PI3Kδ Inhibitor Parsaclisib Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-cell Lymphoma [Phase 1]
Phase 1 trial evaluating parsaclisib combined with chidamide for relapsed/refractory peripheral T-cell lymphoma has been terminated.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Safety and Efficacy of Anti-EBV Autologous TCR-T Cell Injection in Relapsed/Refractory EBV-Positive Lymphoma [EARLY_Phase 1]
A Phase 1 trial assessing safety and preliminary efficacy of anti-EBV autologous TCR-T cell therapy in relapsed/refractory EBV-positive lymp…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL) [Phase 2]
This Phase II study evaluates single-agent Brentuximab Vedotin in relapsed/refractory CD30-low mature T-cell lymphomas; the trial has comple…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19) [Phase 3]
A Phase 3 multinational trial evaluating golidocitinib versus investigator's choice in relapsed/refractory peripheral T-cell lymphoma is cur…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL [Phase 3]
A Phase 3 trial is evaluating belinostat or pralatrexate in combination with CHOP versus CHOP alone for peripheral T cell lymphoma. Recruitm…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Combination Therapy With Tazemetostat in Relapsed and Refractory Peripheral T-cell Lymphoma [Phase 1, Phase 2]
Clinical trial update describing Phase 1 and Phase 2 evaluation of tazemetostat in relapsed and refractory peripheral T-cell lymphoma, with …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma [Phase 2]
This is a Phase 2 clinical trial update for a CD30-targeted CAR T-cell therapy for relapsed/refractory CD30-positive peripheral T-cell lymph…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial of ST-001 nanoFenretinide for relapsed/refractory T-cell non-Hodgkin lymphoma is currently recruiting, targeting multiple T-ce…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Romidepsin Maintenance After Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial update on romidepsin as maintenance therapy after allogeneic stem cell transplantation. The study status is completed and incl…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Tucidinostat in Combination With CHOP in Newly Diagnosed Peripheral T-Cell Lymphoma With Follicular Helper of T Cell Phenotype [Phase 3]
A Phase 3 trial evaluating Tucidinostat in combination with CHOP for newly diagnosed peripheral T-cell lymphoma with follicular helper T-cel…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I) [Phase 1]
Phase I clinical trial update for BR101801 in adults with advanced hematologic malignancies; the study has completed.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of pembrolizumab and olaparib for relapsed or refractory peripheral T-cell lymphoma, cur…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Phase 1 Study of PTX-100 in Patients With Advanced Malignancies With PTCL Expansion Cohort [Phase 1]
The update announces the completion of a Phase 1 trial of PTX-100 in patients with advanced malignancies, including a PTCL expansion cohort.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: To Observe the CD7-targeted CAR-T Therapy in the Treatment of r/r PTCL [Phase 1]
A Phase 1 clinical trial is investigating a CD7-targeted CAR-T therapy for relapsed/refractory peripheral T-cell lymphoma and is currently r…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Linperlisib Combined With Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating the combination of linperlisib with chidamide for relapsed or refractory peripheral T-cell lymph…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Phase 2 Study of AFM13 in Combination With AB-101 in Subjects With R/R HL and CD30+ PTCL [Phase 2]
A Phase 2 study evaluating AFM13 in combination with AB-101 for relapsed or refractory Hodgkin lymphoma and CD30+ peripheral T-cell lymphoma…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma [EARLY_Phase 1]
An early-phase 1 trial evaluating chemoimmunotherapy followed by an allogeneic stem cell transplant for natural killer cell lymphoma/leukemi…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Study of Brentuximab Vedotin in Patients With R/R PTCL Treated With Gemcitabine [Phase 2]
Phase 2 study of brentuximab vedotin in relapsed/refractory peripheral T-cell lymphoma treated with gemcitabine has completed.
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Golidocitinib With Azacitidine and Chidamide in Patients With Peripheral T-cell Lymphoma. [Phase 2]
Phase 2 trial evaluating a triplet regimen of golidocitinib with azacitidine and chidamide in peripheral T-cell lymphoma; the study is not y…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Polyspecific Antibodies in Lymphoproliferative T-cell Disorders [Phase 1, Phase 2]
A Phase 1/2 clinical trial of polyspecific antibodies for peripheral T-cell lymphoma is currently recruiting, sponsored by Xenothera SAS.
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Chidamide Combined With Brentuximab Vedotin Regimen for CD30+ PTCL Patients [NA]
A clinical trial evaluating chidamide in combination with Brentuximab Vedotin for CD30-positive peripheral T-cell lymphoma is currently recr…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Bendamustine Combined With Chidamide and Lenalidomide for Relapsed and Refractory PTCL Patients [NA]
This clinical trial update reports a triplet regimen of bendamustine, chidamide, and lenalidomide for relapsed and refractory peripheral T-c…