Periodontitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis [Phase 2]
A Phase 2 clinical trial evaluated the efficacy of a locally delivered rosemary extract gel for managing periodontitis; the study has comple…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Predictive Role of the Full-mouth Plaque Score on the Outcomes of Non-surgical Periodontal Therapy.
A clinical trial is evaluating whether the full-mouth plaque score can predict the outcomes of non-surgical periodontal therapy in periodont…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Non-inferiority Study of Laser Combined With Ultrasonic Debridement Therapy (LCUDT) Versus Manual Combined With Ultrasonic Debridement Therapy (MCUDT) in the Treatment of Periodontitis [NA]
A non-inferiority study comparing laser combined with ultrasonic debridement therapy (LCUDT) to manual combined with ultrasonic debridement …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Inflammation in Clear Aligners With and Without Attachments
A University of Nebraska-sponsored clinical trial is investigating inflammation in clear aligners with and without attachments for periodont…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Association Between Periodontitis and Chronic Kidney Disease
This clinical trial investigates the potential association between periodontitis and chronic kidney disease, and its status is not yet recru…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Development and Validation of the Periodontal Map Derived From IOS and CBCT Registration for Diagnosis and Treatment Planning in Moderate-to-severe Periodontitis
This clinical trial update describes development and validation of a periodontal map derived from intraoral scanner (IOS) and CBCT registrat…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues
A clinical trial is investigating ultra-high frequency ultrasonography as a tool to study gingival tissues in gingivitis and periodontitis, …
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Effect of Non-surgical Treatment of Periodontitis Patients Focusing on Inflammatory Mediators in Gingival Crevicular Fluid
A completed clinical trial evaluated non-surgical treatment of periodontitis with a focus on inflammatory mediators in gingival crevicular f…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Novel Bone Substitute (ALBO-OS) in Patients With Periodontal Disease or Who Need Alveolar Preservation [NA]
This entry reports the completion of a clinical trial evaluating the bone substitute ALBO-OS in patients with periodontitis or who require a…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Evaluation of Mandibular Bone Microstructure Changes After Periodontal Treatment (M-BONE Study)
A completed clinical trial evaluating changes in mandibular bone microstructure after periodontal treatment in patients with periodontitis a…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Relationship Between Nutritional Status, Physical Activity and Periodontal Status
A completed study examining how nutritional status and physical activity relate to periodontal health. The study highlights associations wit…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Salivary and Serum Inflammatory Biomarkers in Diabetic Nephropathy by Periodontal Status
This completed trial investigates salivary and serum inflammatory biomarkers in diabetic nephropathy and how periodontal status (periodontit…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Hyaluronic Acid and Albumin-PRF in Non-Surgical Periodontal Therapy [NA]
This clinical trial update describes a study evaluating hyaluronic acid and Albumin-PRF as adjuncts in non-surgical periodontal therapy for …
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Predicting Periodontal Treatment Success Using Machine Learning in Periodontitis Patients
This completed clinical trial investigates using machine learning to predict the success of periodontal treatment in patients with periodont…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+D
This clinical trial update describes an oral-periodontal evaluation and assessment of oral fluid biomarkers in patients with chronic hepatit…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Blood Glucose Screening in Patients With Advanced Periodontits: the Role of Specialist Periodontal Care in Identifying Hyperglycaemia and Supporting Patient Centered Treatment
This clinical trial update describes enrollment-by-invitation for a study investigating whether specialist periodontal care can help identif…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
This clinical trial uses single-cell and spatial transcriptomics to profile gingival tissues from individuals with aggressive and chronic pe…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: The Effect of Non-surgical Periodontal Treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5 Levels
A completed clinical trial evaluating the effect of non-surgical periodontal treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Clinical Efficacy of NST With Adjunctive Local Delivery of Ozonated Olive Versus Curcumin Gel in Stage II Grade B Periodontitis. [NA]
A completed clinical trial comparing adjunctive local delivery of ozonated olive oil gel versus curcumin gel for treatment of Stage II Grade…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis [NA]
A completed clinical trial evaluating regular home-use of dual-light photodynamic therapy for generalized chronic periodontitis (moderate to…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Tinder Fungus as an Adjunct to Non-surgical Periodontal Therapy for Periodontitis [NA]
The document reports a not-yet-recruiting clinical trial sponsored by Sigmund Freud PrivatUniversitat evaluating Tinder Fungus as an adjunct…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Biologicals in Management of Intra-Bony Defects [NA]
An ongoing clinical trial sponsored by KU Leuven is evaluating biological therapies for managing intrabony defects in periodontitis; the stu…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid [NA]
This clinical trial investigates a non-surgical treatment for periodontitis using adjunctive sodium hypochlorite with amino acids and cross-…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Effects of Non-Surgical Periodontal Treatment on Inflammatory and Bone Markers in Periodontitis Patients [NA]
This clinical trial registration describes a study evaluating the effects of non-surgical periodontal treatment on inflammatory and bone mar…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus [NA]
A clinical trial is evaluating whether periodontal treatment with antimicrobial photodynamic therapy reduces halitosis in patients with Type…