Periodontitis
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Evaluation of Effect of Non-surgical Periodontal Treatment on Patient's Self Perception of Esthetics [NA]
The record describes a study evaluating non-surgical periodontal treatment's effect on self-perceived esthetics in periodontitis. The trial …
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Effects of Omega-3 as an Adjunct to Non-Surgical Periodontal Therapy on Chemerin Level in Periodontitis Patients With Diabetes: A Randomized Clinical Trial [NA]
Completed randomized clinical trial testing omega-3 fatty acids as an adjunct to non-surgical periodontal therapy to assess effects on cheme…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: The Application of a Fasting- Mimicking Diet in Periodontitis: A Feasibility Study [NA]
This is a completed feasibility trial evaluating the use of a fasting-mimicking diet in people with periodontitis.
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CLINICAL_TRIALS research · 2024-06-11Clinical Trial Update: (DDS) in India: a Screening Tool to Identify Prediabetes and Undiagnosed Type 2 Diabetes in Dental Settings
This ClinicalTrials.gov entry describes a planned screening-tool study in India to identify prediabetes and undiagnosed type 2 diabetes in d…
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: PROSpECT-PRIOR-2-CHEMO: PRIOR Dental Intervention Before Chemo to Reduce Chemotherapy Complications [NA]
This trial update describes PROSpECT-PRIOR-2-CHEMO, a study evaluating a prior dental intervention before chemotherapy to reduce chemotherap…
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: GCF Bax and Bcl-xl Levels in Periodontitis
This completed clinical trial investigates Bax and Bcl-xl protein levels in gingival crevicular fluid from individuals with periodontitis an…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Non-surgical Step 3 Periodontal Treatment With/Without Adjunctive Protocol - Pilot RCT. [Phase 4]
Phase 4 pilot randomized trial evaluating non-surgical periodontal therapy with or without an adjunctive protocol has completed. Results for…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: Multi-omics Analysis of Oral-gut Microbial Profiles [NA]
A recruiting clinical study (NCT06261515) from the University of Turin is examining multi-omics analyses of oral and gut microbial profiles …
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Non-Incised Papilla Flap in Deep Supraossous Defects [NA]
This clinical trial update shows that the Ain Shams University-sponsored study on a Non-Incised Papilla Flap technique for deep supraosseous…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Human Dental Pulp Mesenchymal Stem Cells for the Treatment of Chronic Periodontitis Patients [Phase 2]
A Phase 2 clinical trial evaluating human dental pulp mesenchymal stem cells for chronic periodontitis is currently recruiting at Peking Uni…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Impact of Bruxism in the Outcome of Subgingival Instrumentation for the Management of Stage 2 and Stage 3 Periodontitis. [NA]
The document notes a recruiting clinical trial evaluating the impact of bruxism on outcomes of subgingival instrumentation in stage 2–3 peri…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease
A university-sponsored clinical trial evaluating salivary biomarkers (SuPAR, HIF-1α, E-cadherin, Galectin-3, IL-4, IL-10, TNF-α) across diff…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Impact of Subgingival Instrumentation on Jaw Symptoms of Probable Bruxers Among Patients With Periodontitis [NA]
This clinical trial entry describes a study evaluating subgingival instrumentation's effect on jaw symptoms in probable bruxers with periodo…
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FDA approval · 2024-05-24FDA Approved: ARESTIN — Supplemental Application (OraPharma, Inc.)
FDA approved a supplemental application for ARESTIN (minocycline hydrochloride) by OraPharma, Inc., indicating a regulatory change to the pr…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Assessment of Masticatory Performance in Periodontitis
A clinical trial update for a study measuring masticatory performance in chronic periodontitis, sponsored by the Postgraduate Institute of D…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Allograft With Enamel Matrix Derivative Versus Allograft Alone in the Treatment of Intrabony Defects . [NA]
A completed clinical trial comparing allograft with enamel matrix derivative to allograft alone for the treatment of intrabony periodontal d…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Impact of Subgingival Instrumentation on Masticatory Performance and Psychological Distress [NA]
A clinical trial evaluating the impact of subgingival instrumentation on masticatory performance and psychological distress in people with p…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Evaluation of Photodynamic Therapy in Pieces With Presence of Fistula. [NA]
A clinical trial assessing photodynamic therapy for periodontitis with fistula is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Treatment of Periodontal Disease in Patients With Alzheimer's Disease [NA]
A clinical trial is planned to evaluate periodontal treatment in patients with Alzheimer's disease; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Impact of Periodontal Therapy on Mental Health Parameters [NA]
A clinical trial evaluating whether periodontal therapy affects mental health parameters in individuals with periodontitis and depression; t…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Relationship Between Major Depression and Periodontal Diseases
A clinical trial conducted by Universidad Complutense de Madrid is investigating the relationship between major depressive disorder and peri…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Impact of a Newly Formulated Toothpaste in Tooth Staining Associated With Chlorhexidine Rinses [NA]
A completed clinical trial from Universidad Complutense de Madrid evaluated a newly formulated toothpaste designed to reduce staining associ…
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CLINICAL_TRIALS other · 2024-05-09Clinical Trial Update: Periodontal and Cardiovascular Diseases Project [NA]
The clinical trial 'Periodontal and Cardiovascular Diseases Project' (NCT02716259) has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study [Phase 1]
Phase 1 trial completion evaluating diode laser photo-activation for decontaminating periodontal pockets and supporting pocket reduction in …
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Validation of the Clinical and Antimicrobial Effectiveness of a Clorexidine and Sodium DNA Based Mouthwash in Patients With Stage III and IV Periodontitis [NA]
A completed clinical trial evaluating the clinical and antimicrobial effectiveness of a chlorhexidine and sodium DNA-based mouthwash in pati…