Patent Foramen Ovale
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: GORE® CARDIOFORM Septal Occluder Migraine Clinical Study [NA]
Clinical trial results for the GORE CARDIOFORM Septal Occluder in patients with migraine and patent foramen ovale have been posted, with the…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Comparison of the Effect of Medication Therapy in Alleviating Migraine With Patent Foramen Ovale [Phase 2]
A Phase 2 trial comparing the effect of medication therapy on migraine symptoms in patients with patent foramen ovale; the study has complet…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Abbott Structural Heart Device Registry
Abbott's Structural Heart Device Registry is currently recruiting to evaluate outcomes across several congenital and structural heart condit…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pulmonary Embolism and Right-to-Left Shunts
A Tufts Medical Center-led clinical trial update shows recruitment ongoing for a study on pulmonary embolism and right-to-left shunt-related…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure [NA]
A clinical trial is evaluating medical therapy with or without transcatheter closure of a patent foramen ovale in patients with patent foram…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years [Phase 3]
A Phase 3 clinical trial is evaluating PFO closure versus oral anticoagulants or antiplatelet therapy to prevent recurrent stroke in adults …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke [NA]
A clinical trial update describing the plan to discontinue antithrombotic therapy after patent foramen ovale closure in young patients with …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: NobleStitch EL STITCH Trial is a PFO Comparative Trial [NA]
The NobleStitch EL STITCH Trial is a comparative study evaluating patent foramen ovale closure for stroke prevention and is currently recrui…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Trevisio Post-Approval Study
Trevisio post-approval study by Abbott Medical Devices has completed and posted results (as of 2026-03-16). The study covers patent foramen …
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study [NA]
Clinical trial update for the PROTEA-PFO early feasibility study evaluating percutaneous repair of the atrial septum with a novel PFO occlud…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion [NA]
This clinical trial update describes a study comparing the Occlutech Flex II PFO Occluder to standard PFO occlusion in patients with stroke …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Non-Invasive Detection of Right-to-Left Cardiac Shunts
This clinical trial update describes a study evaluating a non-invasive method to detect right-to-left cardiac shunts in patients with patent…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound Device [NA]
A recruiting clinical trial evaluating a non-invasive SONAS ultrasound device to detect pulmonary right-to-left shunts in patients with here…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: CeraFlex PFO Closure System PMCF Study
A post-market clinical follow-up (PMCF) study for Lifetech Scientific's CeraFlex PFO Closure System is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine [NA]
A clinical trial comparing biodegradable and metal occluders for patients with patent foramen ovale and migraine is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Japan Post Marketing Surveillance of the GORE® CARDIOFORM Septal Occluder
Post-marketing surveillance update for the GORE CARDIOFORM Septal Occluder in Japan, monitoring safety and outcomes related to stroke and TI…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study [NA]
The REDUCE Post Approval Study is evaluating antiplatelet strategies to reduce recurrent stroke in patients with patent foramen ovale treate…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Cerebral Microembolization Associated With PFO Closure
This clinical trial update notes a study investigating cerebral microembolization associated with closure of patent foramen ovale (PFO) and …
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Internal Microstructure of Patent Foramen Ovale Related to Stroke
A clinical trial is recruiting to investigate the internal microstructure of the patent foramen ovale and its relationship to stroke. The sp…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Comparison of Lower vs Upper Extremity Injection Agitated Saline to Identify Patent Foramen Ovale With Echocardiography [NA]
Completed clinical trial comparing lower vs upper extremity injection of agitated saline to identify patent foramen ovale using echocardiogr…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study
A clinical trial from National University Hospital, Singapore, investigating the relationship between ischemic stroke and patent foramen ova…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
Update on the SECRETO Study Consortium trial investigating causes, triggers, and outcomes of cryptogenic stroke in young adults. The study i…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Atrial Fibrillation Before and After Patent Foramen Ovale Closure Study
This update provides information on a clinical trial examining atrial fibrillation before and after patent foramen ovale closure. The study …
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: WSO BEAT STROKE Initiative [NA]
This clinical trial update describes the WSO BEAT STROKE Initiative evaluating stroke and patent foramen ovale with related atrial fibrillat…
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CLINICAL_TRIALS withdrawal · 2025-03-20Clinical Trial Update: Close Obstructive Sleep Apnea (OSA) Trial [NA]
A clinical trial investigating a treatment for obstructive sleep apnea in patients with patent foramen ovale has been withdrawn.