Parkinsonism
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: West Sweden Parkinson Objective Measurement Registry Study
The West Sweden Parkinson Objective Measurement Registry study (NCT03130595) is currently active but not recruiting. It aims to collect obje…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Biomarkers in Parkinsonian Syndromes
An ongoing clinical trial is recruiting to investigate biomarkers across Parkinsonian syndromes, including Parkinson's disease and Progressi…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Head-up Tilt Sleeping to Alleviate Orthostatic Hypotension, Supine Hypertension and Nocturia in Parkinson's Disease [NA]
This clinical trial evaluates whether head-up tilt sleeping can reduce orthostatic hypotension, supine hypertension, and nocturia in people …
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Diaphragmatic Thickness and Pulmonary Function in Parkinson's Disease
A completed clinical trial evaluating diaphragmatic thickness and pulmonary function in Parkinson's disease patients. The study is sponsored…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Efficacy and Safety of Astragalus for Non-motor Symptoms of α-Synucleinopathy [Phase 2]
Phase 2 clinical trial assessing efficacy and safety of Astragalus for non-motor symptoms in α-synucleinopathy (Parkinsonism).
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FDA approval · 2022-09-21FDA Approved: CARBIDOPA-LEVODOPA — Original Application (Advagen Pharma Ltd.,)
The FDA approved Advagen Pharma's original application for a generic carbidopa-levodopa product.
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CLINICAL_TRIALS trial_result · 2021-11-23Clinical Trial Update: An Open-Label Tolerability and Exploratory Efficacy Study of Zonisamide for Dyskinesias in Parkinson's Disease [Phase 4]
Open-label Phase 4 trial updating tolerability and exploratory efficacy of zonisamide for dyskinesias in Parkinson's disease; study suspende…
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Novel Neuroimage Study in Tauopathies With Parkinsonism [Phase 2]
Phase 2 clinical trial update for a novel neuroimage study in tauopathies presenting with parkinsonism has completed.
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CLINICAL_TRIALS trial_result · 2020-07-10Clinical Trial Update: Evaluation of Safety and Tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells for Parkinson's Disease [Phase 1, Phase 2]
Clinical trial update on safety and tolerability of fetal mesencephalic dopamine neuronal precursor cells for Parkinson's disease (Phase 1/P…
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CLINICAL_TRIALS trial_result · 2019-03-22Clinical Trial Update: Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates [Phase 4]
Phase 4 trial evaluating varenicline for smoking cessation in schizophrenia with antipsychotic-induced neurological symptoms as correlates; …
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Degenerative Nigrostriatal Dysfunction in Drug-induced Parkinsonism
This clinical trial update examines degenerate nigrostriatal dysfunction in drug-induced Parkinsonism. The current trial status is not discl…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes
This entry notes the completion of a clinical trial evaluating transcranial duplex scanning and SPECT imaging in Parkinsonian syndromes cond…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Exploratory Study Using Nanotechnology to Detect Biomarkers of Parkinson's Disease From Exhaled Breath
This completed exploratory trial investigates using nanotechnology to detect biomarkers of Parkinson's disease from exhaled breath. The stud…
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: A Trial of 18F-AV-133 Positron Emission Tomography (PET) Imaging to Differentiate Subjects With Parkinson's Disease (PD) From Other Movement Disorders [Phase 2, Phase 3]
The completed Phase 2/3 trial evaluated 18F-AV-133 PET imaging for distinguishing Parkinson's disease from other movement disorders.
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism [Phase 2]
A Phase 2 clinical trial testing clonazepam for REM sleep behavior disorder in patients with Parkinsonism has completed.
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: 2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism [EARLY_Phase 1]
A Phase 1 PET tracer trial for tauopathy in unclassified parkinsonism (progressive supranuclear palsy and multi-system atrophy) has complete…
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Mobilaser Study to Help With People Who Are Having Problems With Their Gait [EARLY_Phase 1]
A Mayo Clinic early-phase 1 trial evaluating Mobilaser for gait problems in Parkinson's disease and Parkinsonism has completed.
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FDA approval · 2015-11-05FDA Approved: CARBIDOPA AND LEVODOPA — Supplemental Application (Dr. Reddy's Laboratories Inc)
FDA approved Dr. Reddy's Laboratories' supplemental application for a generic carbidopa-levodopa product. This expands access to treatment f…
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CLINICAL_TRIALS trial_result · 2013-01-08Clinical Trial Update: Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes [NA]
This clinical trial update studied biomechanical gait parameters in patients with Parkinson's disease and Parkinsonian syndromes. The trial,…
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FDA approval · 2012-11-28FDA Approved: BENZTROPINE MESYLATE — Original Application (Leading Pharma, LLC)
FDA approved the original ANDA for benztropine mesylate from Leading Pharma, LLC, making a generic version available. It is indicated for th…
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CLINICAL_TRIALS trial_result · 2012-08-29Clinical Trial Update: A Study to Assess Changes in Clinical Management After DaTSCAN Imaging of Subjects With Clinically Uncertain Parkinsonism or an Illness With Similar Symptoms [Phase 4]
Phase 4 study evaluating whether DaTSCAN imaging changes clinical management in patients with clinically uncertain parkinsonism or similar s…
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CLINICAL_TRIALS trial_result · 2010-11-10Clinical Trial Update: Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism [NA]
A terminated clinical trial evaluated the efficacy and tolerability of ramelteon in patients with REM sleep behavior disorder and Parkinsoni…
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FDA approval · 2009-07-28FDA Approved: BENZTROPINE MESYLATE — Original Application (Fresenius Kabi USA, LLC)
FDA approved the original application for benztropine mesylate (generic) by Fresenius Kabi USA, LLC, expanding access to treatment for Parki…
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CLINICAL_TRIALS trial_result · 2008-10-07Clinical Trial Update: Botulinum Toxin for Treatment of Seborrhic Dermatitis in Parkinsonian Patients [Phase 1]
Phase 1 trial investigating botulinum toxin for seborrheic dermatitis in Parkinsonian patients; current status is unknown.
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CLINICAL_TRIALS research · 2008-04-04Clinical Trial Update: The Association of Neurotoxin Exposure With Parkinson's Disease and Parkinsonism in World War II Veterans and Other Men
This completed clinical trial update examines the association between neurotoxin exposure and Parkinson's disease and parkinsonism among Wor…