Parkinson Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: LRRK2 Mutation and Parkinson's Disease [Phase 1]
Phase 1 trial sponsored by GlaxoSmithKline investigating LRRK2 mutation-related Parkinson disease has been terminated.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Quantification of the Antidyskinetic Effect of Amantadine and Topiramate in Parkinson's Disease [NA]
A terminated clinical trial evaluating the antidyskinetic effects of amantadine and topiramate in Parkinson's disease; results posted in 201…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Non-invasive Measurement of Brain Oxygen Levels in People With Subthalamic Deep Brain Stimulators [NA]
Completed clinical trial evaluating a non-invasive method to measure brain oxygen levels in people with subthalamic deep brain stimulators. …
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CLINICAL_TRIALS research · 2017-05-03Clinical Trial Update: Apomorphine in Parkinson's Disease Patients With Visual Hallucinations [Phase 2]
Clinical trial update describes a Phase 2 study of apomorphine in Parkinson's disease patients experiencing visual hallucinations.
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CLINICAL_TRIALS research · 2017-05-03Clinical Trial Update: Comparison of the Incidence of Dyskinesia in Parkinson's Disease Who Were Treated With Amantadine or Dopamine Agonist
A clinical trial comparing the incidence of dyskinesia in Parkinson's disease patients treated with amantadine versus a dopamine agonist; th…
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CLINICAL_TRIALS research · 2017-05-03Clinical Trial Update: Temporal Relationship Between Motor Fluctuations and Nonmotor Fluctuations
An ongoing clinical trial at Seoul National University Hospital is investigating the temporal relationship between motor fluctuations and no…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease [NA]
This completed clinical trial evaluated whether swallowing and breathing exercises improve dysphagia in people with Parkinson disease.
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CLINICAL_TRIALS withdrawal · 2017-04-27Clinical Trial Update: Hub and Spoke, Comparative Outcomes for Parkinson's Disease Treated With Deep Brain Stimulation [NA]
The clinical trial NCT02541617 investigating hub-and-spoke deep brain stimulation for Parkinson's disease has been withdrawn.
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CLINICAL_TRIALS research · 2017-04-25Clinical Trial Update: Investigating Therapies for Freezing of Gait [NA]
A clinical trial update on therapies for freezing of gait in Parkinson's disease; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Carbidopa-Levodopa (CD-LD) ER Alone or in Combination With CD-LD IR to IPX066 Followed by IPX066 Extension Safety Study [Phase 3]
Phase 3 trial update comparing carbidopa-levodopa extended-release alone or with immediate-release in IPX066 follow-up and a safety extensio…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Safety and Efficacy Study of Human ESC-derived Neural Precursor Cells in the Treatment of Parkinson's Disease [Phase 1, Phase 2]
Clinical trial update on a human embryonic stem cell–derived neural precursor cell therapy for Parkinson's disease. The study is a Phase 1/2…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Effect of Food on Opicapone [Phase 1]
A Phase 1 study evaluated the effect of food on the pharmacokinetics of opicapone in Parkinson disease and has completed.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Cholinergic Nicotinic Receptors and Cognition in PD
This update reports on a completed clinical trial investigating the role of cholinergic nicotinic receptors in cognitive function in Parkins…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: rTMS for Motor and Mood Symptoms of Parkinson's Disease [NA]
This clinical trial evaluated repetitive transcranial magnetic stimulation (rTMS) for motor and mood symptoms in Parkinson's disease; result…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: A Randomized Trial to Evaluate Ampyra for Gait Impairment in Parkinson's Disease [Phase 1, Phase 2]
A randomized trial evaluating Ampyra for gait impairment in Parkinson's disease has completed Phase 1 and Phase 2 with results posted.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Mild Cognitive Impairment in Parkinson's Disease [Phase 4]
Phase 4 clinical trial evaluating an intervention for Parkinson's disease with mild cognitive impairment has completed; results were posted …
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon [Phase 2]
Phase 2 trial evaluating the efficacy and tolerability of nebicapone in Parkinson disease patients with wearing-off; the study has completed…
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Impact of Rehabilitation in Quality of Life in PD [NA]
A completed clinical trial update evaluating the impact of rehabilitation on quality of life in patients with Parkinson disease.
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CLINICAL_TRIALS research · 2017-04-05Clinical Trial Update: The Effects of Treadmill Training With Visual and Auditory Cues on Gait Parameters in Parkinsonian Patients in Advanced Stages of Disease. [NA]
Update on a clinical trial examining whether treadmill training with visual and auditory cues improves gait parameters in advanced Parkinson…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Effectiveness of Intensive Rehabilitation in Advanced Stages of Parkinson's Disease. [NA]
This document summarizes a clinical trial evaluating the effectiveness of intensive rehabilitation in advanced Parkinson disease. The status…
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CLINICAL_TRIALS research · 2017-04-04Clinical Trial Update: Handwriting Rehabilitation in Parkinson Disease [NA]
This document notes a clinical trial exploring handwriting rehabilitation for people with Parkinson disease, with the current status listed …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors [Phase 4]
Phase 4 clinical trial update evaluating rotigotine versus placebo for nocturnal hypokinesia in Parkinson's disease, assessed with wearable …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg [Phase 1]
This Phase 1 trial evaluated the steady-state effect of the investigational compound BIA 6-512 on the pharmacokinetics of a single-dose Levo…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: A Study to Compare Pharmacokinetics and Pharmacodynamics of IPX066 to Standard Carbidopa-Levodopa [Phase 2]
Phase 2 trial comparing PK/PD of IPX066 to standard carbidopa-levodopa in Parkinson's disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes [NA]
A clinical trial evaluating magnetic resonance imaging in the diagnosis of Parkinsonian syndromes has been terminated.