Parkinson Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-11-17Clinical Trial Update: GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures [NA]
A completed clinical trial investigating GPR109A and niacin in Parkinson's disease outcome measures; results posted in 2021.
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CLINICAL_TRIALS withdrawal · 2021-11-16Clinical Trial Update: Keppra IV for the Treatment of Motor Fluctuations in Parkinson's Disease [Phase 4]
A Phase 4 trial of Keppra IV for motor fluctuations in Parkinson's Disease was withdrawn.
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FDA approval · 2021-11-12FDA Approved: DHIVY — Original Application (Avion Pharmaceuticals, LLC)
FDA approves DHIVY, an original-application carbidopa/levodopa product from Avion Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2021-11-08Clinical Trial Update: Trial of Ursodeoxycholic Acid (UDCA) for Parkinson's Disease: The "UP" Study [Phase 2]
Phase 2 trial of ursodeoxycholic acid (UDCA) for Parkinson's disease has been completed.
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: A Study of the Efficacy and Safety of Carbidopa-Levodopa Extended-Release Tablets in Patients With Parkinson's Disease [Phase 2]
Phase 2 trial update on the efficacy and safety of carbidopa-levodopa extended-release tablets in Parkinson's disease.
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CLINICAL_TRIALS trial_result · 2021-10-27Clinical Trial Update: Modafinil for Freezing of Gait (FOG) in Parkinson's Disease (PD) [Phase 2]
A Phase 2 trial evaluating modafinil for freezing of gait in Parkinson's disease has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2021-10-27Clinical Trial Update: Genetic Influences on Response to Gait Rehabilitation in Parkinson's Disease [NA]
A completed clinical trial examining how genetic factors influence response to gait rehabilitation in Parkinson's disease; results posted in…
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Trial Comparing Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Parkinson's Disease [NA]
A terminated clinical trial comparing awake versus asleep deep brain stimulation for Parkinson's disease has posted results.
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CLINICAL_TRIALS trial_result · 2021-10-20Clinical Trial Update: The Therapeutic Effect of Transcranial Direct Current Stimulation on Depression in Parkinson's Disease [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial investigated the effect of transcranial direct current stimulation on depression in Parkinson's diseas…
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CLINICAL_TRIALS trial_result · 2021-10-18Clinical Trial Update: Simvastatin as a Neuroprotective Treatment for Moderate Parkinson's Disease [Phase 2]
Phase 2 clinical trial investigating simvastatin as a neuroprotective treatment for moderate Parkinson's disease has completed.
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FDA approval · 2021-10-14FDA Approved: BENZTROPINE MESYLATE — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved the original application for benztropine mesylate (generic) from Hikma Pharmaceuticals USA Inc., for use in treating Parkinsoni…
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CLINICAL_TRIALS trial_result · 2021-10-14Clinical Trial Update: Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson's Disease With Neuropsychiatric Symptoms Treated With Pimavanserin or Low-Dose Quetiapine [Phase 2]
Phase 2 trial evaluating safety and daytime sedation in Parkinson's disease with neuropsychiatric symptoms comparing pimavanserin to low-dos…
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FDA approval · 2021-10-05FDA Approved: CARBIDOPA AND LEVODOPA — Original Application (Radha Pharmaceuticals Inc)
The FDA approved Radha Pharmaceuticals Inc's original ANDA for a generic carbidopa-levodopa product, used to treat Parkinson's disease.
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EMA approval · 2021-09-28EMA Authorised: Entacapone Teva (entacapone) — Teva Pharma B.V.
Entacapone Teva has been authorised for use in the treatment of Parkinson's disease in the EU.
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CLINICAL_TRIALS trial_result · 2021-08-31Clinical Trial Update: Rasagiline in Cognitive-impairment Related Depression: AzileCt in COgnitive-impairment Related DepressiOn [Phase 4]
Phase 4 trial update for rasagiline (AzileCt) in cognitive-impairment related depression associated with Parkinson's disease; study complete…
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: The Effect of Donepezil on Gait and Balance in Parkinson's Disease [Phase 4]
Phase 4 trial updating results on the effect of donepezil on gait and balance in Parkinson's disease.
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CLINICAL_TRIALS trial_result · 2021-08-26Clinical Trial Update: Effects of Lingzhi on Disease Progression in Patients With Untreated Early Parkinson's Disease [Phase 3]
Phase 3 clinical trial update investigating Lingzhi for slowing disease progression in untreated early Parkinson's disease.
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: Use of Mesenchymal Stem Cells (MSCs) Differentiated Into Neural Stem Cells (NSCs) in People With Parkinson's (PD). [Phase 1, Phase 2]
Clinical trial investigating mesenchymal stem cells differentiated into neural stem cells for Parkinson's disease across Phase 1/Phase 2.
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FDA approval · 2021-08-20FDA Approved: AMANTADINE HYDROCHLORIDE — Original Application (Patrin Pharma, Inc.)
FDA approved Patrin Pharma, Inc.'s original application for amantadine hydrochloride, enabling production and marketing of this generic drug…
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: A Pilot Study of Mirabegron and Behavioral Modification Including Pelvic Floor Exercise for Overactive Bladder in Parkinson's Disease (MAESTRO) [Phase 4]
Pilot Phase 4 trial evaluating mirabegron plus pelvic floor exercise for overactive bladder symptoms in Parkinson's disease; results posted …
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FDA approval · 2021-08-06FDA Approved: XADAGO — Supplemental Application (MDD US Operations LLC, a subsidiary of Supernus Pharmaceuticals, Inc.)
FDA approved a supplemental application for XADAGO (safinamide mesylate) submitted by MDD US Operations LLC, a subsidiary of Supernus Pharma…
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CLINICAL_TRIALS trial_result · 2021-08-02Clinical Trial Update: A Pilot Study of Terazosin for Parkinson's Disease [Phase 1, Phase 2]
Pilot study of terazosin for Parkinson's disease has completed Phase 1 and Phase 2 trials with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: Cognitive Dysfunction In Parkinson's [NA]
Completed clinical trial investigating cognitive dysfunction in Parkinson's disease; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Dopaminergic Mechanism of Memory Impairment in Parkinson's Disease [Phase 4]
Phase 4 clinical trial update exploring dopaminergic mechanisms of memory impairment in Parkinson's disease.
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Low Frequency Subthalamic Nucleus Deep Brain Stimulation to Improve Verbal Fluency [NA]
A completed study investigating low frequency subthalamic nucleus deep brain stimulation to improve verbal fluency in Parkinson disease pati…