Parkinson Disease

• CLINICAL_TRIALS trial_result · 2025-11-19
  Clinical Trial Update: A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson's Disease [Phase 2]

  This clinical trial update reports results from a Phase 2 randomized, double-blind, placebo-controlled study of IkT-148009 in untreated Park…

• CLINICAL_TRIALS trial_result · 2025-11-19
  Clinical Trial Update: Dual-target, High-dose TMS for PD Patients With FOG [NA]

  A clinical trial evaluating dual-target, high-dose transcranial magnetic stimulation for Parkinson's disease patients with freezing of gait …

• CLINICAL_TRIALS trial_result · 2025-11-18
  Clinical Trial Update: A Study to Test the Safety, Tolerability, and Blood Levels of UCB0022 in Healthy Participants and Participants With Parkinson's Disease [Phase 1]

  This Phase 1 trial assessed the safety, tolerability, and pharmacokinetics (blood levels) of UCB0022 in healthy participants and in people w…

• CLINICAL_TRIALS trial_result · 2025-11-18
  Clinical Trial Update: Study to Assess PDM608 in Healthy Adult Subjects [Phase 1]

  A Phase 1 study evaluating PDM608 in healthy adult subjects has been completed, with Parkinson disease listed as a condition; results were p…

• CLINICAL_TRIALS trial_result · 2025-11-18
  Clinical Trial Update: Mechanical Determinants of Upper Limbs Oscillation During Gait

  The study, sponsored by Istituto Auxologico Italiano, has completed and investigated the mechanical determinants of upper-limb oscillation d…

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• CLINICAL_TRIALS trial_result · 2025-11-18
  Clinical Trial Update: Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study [NA]

  A completed longitudinal trial evaluating mindfulness-based stress reduction for Parkinson's disease; results have been posted.

• CLINICAL_TRIALS trial_result · 2025-11-18
  Clinical Trial Update: Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders [NA]

  A completed clinical trial evaluated the efficacy of virtual reality–based cognitive rehabilitation combined with computer-based cognitive s…

• CLINICAL_TRIALS trial_result · 2025-11-18
  Clinical Trial Update: Serious Game for Parkinson's Disease Patients [NA]

  A completed clinical trial evaluating a serious game intervention for Parkinson's disease patients in France.

• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor [Phase 3]

  Phase 3 trial comparing [18F] LBT-999 PET imaging to DaTSCAN ([123I]-FP/CIT SPECT) for distinguishing Parkinson disease from essential tremo…

• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: Effectiveness of Video-Based Upper Extremity Exercise Program in Parkinson's Disease [NA]

  A completed clinical trial update evaluating a video-based upper-extremity exercise program for people with Parkinson's disease.

• CLINICAL_TRIALS trial_result · 2025-11-13
  Clinical Trial Update: Music Therapy to Prevent Hospital-acquired Delirium in Parkinson's Disease and Dementia With Lewy Bodies [NA]

  A clinical trial evaluating music therapy to prevent hospital-acquired delirium in patients with Parkinson's disease and dementia with Lewy …

• CLINICAL_TRIALS trial_result · 2025-11-12
  Clinical Trial Update: Clinical and Physiological Studies of Tremor Syndromes

  A clinical trial update detailing clinical and physiological studies of tremor syndromes sponsored by the NINDS, covering Parkinson disease,…

• CLINICAL_TRIALS trial_result · 2025-11-10
  Clinical Trial Update: Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability. [NA]

  An update on a Parkinson disease trial evaluating brain stimulation to augment physical therapy for postural instability, with results poste…

• CLINICAL_TRIALS trial_result · 2025-11-04
  Clinical Trial Update: Biomarker Validation Following Sargramostim Treatment in Parkinson's Disease [Phase 1]

  Phase 1 trial evaluating biomarker changes after sargramostim treatment in Parkinson's disease; the study has completed.

• CLINICAL_TRIALS trial_result · 2025-11-04
  Clinical Trial Update: Utilizing Neural Signatures and Virtual Reality to Advance DBS Programming

  A completed Cleveland Clinic study explored using neural signatures and virtual reality to optimize deep brain stimulation programming for P…

• CLINICAL_TRIALS trial_result · 2025-10-31
  Clinical Trial Update: A 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease [Phase 2]

  A Phase 2, 18-month study evaluating the efficacy, safety, tolerability, and pharmacokinetics of oral UCB0599 in early-stage Parkinson's dis…

• CLINICAL_TRIALS trial_result · 2025-10-29
  Clinical Trial Update: Evaluation of Clinical Decision Support System-mPDia for Neurodegenerative Parkinsonism Using MRI Images

  A completed clinical trial evaluating the mPDia clinical decision support system for neurodegenerative Parkinsonism using MRI images has pos…

• CLINICAL_TRIALS trial_result · 2025-10-29
  Clinical Trial Update: A Phase 1b Study of the NLRP3 Inhibitor VENT-02 in Patients With Mild to Moderate Parkinson's Disease [Phase 1, Phase 2]

  A Phase 1b/Phase 2 study of the NLRP3 inhibitor VENT-02 for Parkinson disease has been terminated.

• CLINICAL_TRIALS trial_result · 2025-10-28
  Clinical Trial Update: Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE) [Phase 1]

  Phase 1 trial update evaluating the feasibility and safety of autologous unconditioned peripheral nerve tissue delivery to the substantia ni…

• CLINICAL_TRIALS trial_result · 2025-10-28
  Clinical Trial Update: Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS [Phase 1]

  This clinical-trial update indicates the continuation of a Phase 1 study evaluating implantation of peripheral nerve grafts into Parkinson's…

• CLINICAL_TRIALS trial_result · 2025-10-27
  Clinical Trial Update: Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation [NA]

  This completed clinical trial from North Carolina State University investigated suppressing tremor during grasp using ultrasound imaging and…

• CLINICAL_TRIALS trial_result · 2025-10-27
  Clinical Trial Update: rTMS Treatment of Dysphagia in Parkinson's Patients [NA]

  A completed clinical trial from Ege University evaluated repetitive transcranial magnetic stimulation (rTMS) for treating dysphagia in patie…

• CLINICAL_TRIALS trial_result · 2025-10-15
  Clinical Trial Update: Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback [NA]

  A clinical trial evaluating bilateral closed-loop deep brain stimulation for freezing of gait in Parkinson disease has completed. The approa…

• CLINICAL_TRIALS trial_result · 2025-10-14
  Clinical Trial Update: Personal KinetiGraph® Clinical Validation Study

  The Personal KinetiGraph clinical validation study has completed, summarizing the device’s performance for monitoring movement disorders, in…

• CLINICAL_TRIALS trial_result · 2025-10-14
  Clinical Trial Update: Clinical Trial Evaluating the Efficacy and Safety of AGB101 for Treatment of Parkinson's Disease Related Psychosis [Phase 2]

  This Phase 2 clinical trial is evaluating the efficacy and safety of AGB101 for Parkinson disease-related psychosis and is currently recruit…