Pancreatic Ductal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Phase III, Randomized, Clinical Trial of GnP Combined With SBRT and Serplulimab Versus GnP as First-Line Treatment for Patients With Recurrent or Metastatic Pancreatic Cancer (WGOG-PAN 006/ICSBR-2) [Phase 3]
Phase 3 randomized trial evaluating gemcitabine + nab-paclitaxel (GnP) with SBRT and serplulimab versus GnP alone as first-line therapy for …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer [Phase 2]
Phase 2 clinical trial update examining tumor subtypes in non-metastatic pancreatic cancer patients treated with FOLFIRINOX; the study is cu…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma [Phase 1]
This clinical trial update reports on a Phase 1 pilot study evaluating the combination of pembrolizumab and lenvatinib as second-line treatm…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Mesenchymal CTC Ratio Dynamics Predicts Response and Survival in Pancreatic Ductal Adenocarcinoma With Neoadjuvant/Conversion Therapy
A completed study in pancreatic ductal adenocarcinoma shows that the dynamics of mesenchymal circulating tumor cell ratios during neoadjuvan…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A Clinical Trial Testing the Safety of BNT327 (an Investigational Drug) and How Well it Works When Combined With Chemotherapy for People Who Have Not Been Treated Yet for Pancreatic Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the safety and preliminary efficacy of BNT327 in combination with chemotherapy for treatment-naive pa…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Promitil Treatment of Patients With Solid Tumors Associated With Deleterious Mutations Who Have Progressed After Therapy [Phase 2]
Phase 2 clinical trial evaluating Promitil in patients with solid tumors carrying deleterious mutations that progressed after prior therapy …
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer [Phase 2, Phase 3]
Clinical trial update for the PLATINUM study evaluating second-line platinum-based chemotherapy for metastatic BRCA1/2- or PALB2-associated …
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas [Phase 1]
DR-0202 is being studied in a Phase 1 trial across multiple locally advanced or metastatic carcinomas; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma [EARLY_Phase 1]
This clinical trial update describes an early-phase feasibility study of ketorolac for cachexia in patients with advanced pancreatic ductal …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: A Study of MR001 Combined With Chemotherapy in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) After First-line Therapy [Phase 1, Phase 2]
This document announces a Phase 1/Phase 2 clinical trial evaluating MR001 in combination with chemotherapy for locally advanced or metastati…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma
This entry describes a registry study for BRCA mutation carriers with pancreatic ductal adenocarcinoma, currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of JAB-3312 in adults with advanced solid tumors has been completed, evaluating multiple tumor indications.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Clinical Trial Comparing TQB2868 Injection Combined With Anlotinib Hydrochloride Capsules With Placebo Combined With Chemotherapy as First-line Treatment for Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) [Phase 3]
Phase 3 trial evaluating TQB2868 injection plus Anlotinib capsules with placebo and chemotherapy as first-line treatment for metastatic panc…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: To Evaluate the Safety and Efficacy of RNK08954 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma. [Phase 2]
Clinical trial update announcing a Phase 2 study to evaluate RNK08954 in metastatic pancreatic ductal adenocarcinoma with KRAS G12D mutation…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of a KRAS G12V-specific T cell receptor-transduced T cell therapy for advanced pancreat…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors. [Phase 1]
A Phase I study of [177Lu]Lu-FF58 in patients with advanced solid tumors was terminated. The sponsor was Novartis Pharmaceuticals, and the t…
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CLINICAL_TRIALS withdrawal · 2025-12-24Clinical Trial Update: STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma [Phase 1]
A Phase 1 study of STIL101 for injection across pancreatic ductal adenocarcinoma, colorectal cancer, renal cell carcinoma, cervical cancer, …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Pancreatic Cancer [Phase 2]
Phase II clinical study evaluating HLX43 in advanced pancreatic ductal adenocarcinoma; trial status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted Therapy [Phase 1]
A completed Phase 1 trial assessing a CCR2-targeted PET imaging agent to visualize pancreatic tumors and predict response to standard treatm…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Study of GC203 TIL in PDCA (RJ) [EARLY_Phase 1]
Phase 1 study evaluating GC203 TIL therapy for pancreatic cancer, including pancreatic ductal adenocarcinoma. The trial is currently recruit…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 trial assessing Onvansertib in combination with nanoliposomal irinotecan, leucovorin, and fluorouracil for second-line metastatic …
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA) [Phase 4]
Phase 4 clinical trial evaluating a perioperative bundle including hydrocortisone, octreotide, and a teres ligament patch to reduce postoper…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Pancreatic Cancer Detection Consortium
This Clinical Trial Update describes the Pancreatic Cancer Detection Consortium sponsored by City of Hope Medical Center, currently recruiti…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer [Phase 1]
A Phase 1 clinical trial update describes evaluating a KRAS-targeted vaccine in combination with Balstilimab and Botensilimab for stage IV m…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Phase I/II Study: Allogeneic NK-cell Therapy With Chemotherapy for Post-Surgery PDA or Cholangiocarcinoma Patients [Phase 1, Phase 2]
Phase I/II clinical trial evaluating allogeneic NK-cell therapy with chemotherapy for patients after surgical resection of pancreatic ductal…