Pancreatic Ductal Adenocarcinoma
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Dual-Targeting CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating dual-targeting CAR-NK cells directed at mesothelin and MUC1 for advanced pancreatic ductal adenocarcin…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A First-In-Human Phase I/IIa Study to Evaluate DA 3501 in Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma and Pancreatic Ductal Adenocarcinoma [Phase 1]
First-in-human phase I/IIa trial evaluating DA 3501 in advanced gastric or gastroesophageal cancer and pancreatic ductal adenocarcinoma; cur…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors [Phase 1]
Phase 1 clinical trial update for AVA6103 in patients with locally advanced or metastatic selected solid tumors; the study is currently recr…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Chiauranib in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
This entry reports a Phase 2 clinical trial of chiauranib for locally advanced or metastatic pancreatic ductal adenocarcinoma, sponsored by …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Monthly Alternating NALIRIFOX and GnP in the First-Line Setting for Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
Phase 2 trial evaluating monthly alternating cycles of nal-IRI plus 5-FU/leucovorin (NALIRIFOX) and gemcitabine plus nab-paclitaxel (GnP) as…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
ART0380 is being studied in a Phase 1/2 trial for various advanced or metastatic solid tumors and the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation [Phase 1]
AstraZeneca's Phase I/IIa study of AZD0022 in KRASG12D-mutant tumors has been terminated. The study enrolled adults with advanced solid tumo…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma [Phase 1]
A Phase 1 clinical trial is evaluating the combination of radiotherapy with TTI-101 in patients with border-line resectable and locally adva…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP) [Phase 1, Phase 2]
An update on a Phase 1/Phase 2 trial evaluating neoadjuvant TAMP (PRISM-TAMP) for pancreatic ductal adenocarcinoma, with attention to tumor …
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas [Phase 1]
Phase 1 trial evaluating different doses of BI 765049 in adults with advanced colorectal cancer, gastric cancer, or pancreatic ductal adenoc…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Expanded Access Protocol of ELI-002-102 in Subjects With KRAS/NRAS Mutated Pancreatic Ductal Adenocarcinoma
Expanded access protocol for ELI-002-102 is being offered to patients with KRAS/NRAS-mutated pancreatic ductal adenocarcinoma.
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors [Phase 1, Phase 2]
A clinical trial update indicates that ELI-002 7P is being studied in KRAS/NRAS-mutated solid tumors in Phase 1/Phase 2, with the study curr…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Reinforced Pancreaticojejunostomy With or Without glubran2 [Phase 2]
A Phase 2 clinical trial evaluating reinforced pancreaticojejunostomy with or without Glubran2 surgical adhesive in pancreatic and periampul…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Rimegepant Combined With AG Chemotherapy As First-Line Treatment For Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update evaluating rimegepant in combination with AG chemotherapy as first-line therapy for metastatic pan…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer [Phase 1]
A Phase 1 study evaluating ASP2138 in pancreatic ductal adenocarcinoma, given before surgery and followed by chemotherapy, is currently recr…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Physical Activity and Nutrition to Halt Elevated Risk in the Pancreas Interception Center [NA]
An ongoing clinical trial evaluating whether physical activity and nutrition can reduce elevated pancreatic cancer risk in individuals with …
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Forecasting Occult liveR Metastasis Using an Exosomal Signature for Intelligent Guided Hepatic Targeting
The clinical trial evaluating an exosomal signature for predicting occult liver metastasis in pancreatic ductal adenocarcinoma has completed…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene. [Phase 1]
Phase 1 clinical trial evaluating PF-07985045 alone or with other anti-cancer therapies in adults with advanced solid tumors bearing gene al…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Early Detection Initiative for Pancreatic Cancer [NA]
This entry reports a status update for an early-detection pancreatic cancer trial that is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS [Phase 1, Phase 2]
Betta Pharmaceuticals' BPI-572270 is being studied in Phase 1/2 trials for advanced solid tumors with specific RAS mutations, including non-…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
A Mayo Clinic-sponsored prospective registry for individuals at high risk of pancreatic cancer, including pancreatic ductal adenocarcinoma, …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial from AstraZeneca evaluating a KRAS G12D-targeted TCR-T cell therapy in adults with unresectable, advanced, or metas…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer [Phase 1, Phase 2]
This clinical trial update indicates that AK112 plus Cadonilimab in combination with chemotherapy is being evaluated as first-line treatment…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer [Phase 2]
Phase 2 clinical trial update evaluating combination chemotherapy before and after surgery for localized pancreatic cancer; results have bee…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer [Phase 2]
This is an update on an ongoing Phase 2 clinical trial evaluating maintenance combinatorial myeloid immunotherapy for unresectable pancreati…