Pancreatic Ductal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Selective Plasma Adsorption of Extracellular DNA in Prevention of Intraoperative Metastasis in Pancreatic Cancer (Pilot Study) [NA]
Pilot clinical trial update on selective plasma adsorption of extracellular DNA to prevent intraoperative metastasis in pancreatic ductal ad…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Clinical Study of Lewis Antigen Assay Combined With CA19-9 Assay to Assess Prognosis in Patients With Pancreatic Cancer [NA]
This clinical study is evaluating a Lewis antigen assay combined with CA19-9 to assess prognosis in pancreatic cancer (pancreatic ductal ade…
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CLINICAL_TRIALS withdrawal · 2025-05-02Clinical Trial Update: Patient Derived Cancer Cell Lines in Identifying Molecular Changes in Patients With Previously Untreated Pancreatic Cancer Receiving Gemcitabine Hydrochloride-Based Chemotherapy
A clinical trial investigating patient-derived cancer cell lines in untreated pancreatic ductal adenocarcinoma treated with gemcitabine-base…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial is evaluating Tumor Treating Fields EF-39 in combination with atezolizumab, gemcitabine, and nab-paclitaxel as firs…
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CLINICAL_TRIALS withdrawal · 2025-04-29Clinical Trial Update: CPI-613 in Combination With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer [Phase 2]
A Phase 2 trial evaluating CPI-613 (devimistat) in combination with modified FOLFIRINOX for locally advanced pancreatic ductal adenocarcinom…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Clinical Validation of Immunovia Next-Generation Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer
This completed clinical trial validates Immunovia's next-generation blood biomarker test for detecting pancreatic cancer at early stages.
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma
A clinical trial sponsored by Roswell Park Cancer Institute is recruiting to evaluate an AI-derived biomarker to guide neoadjuvant treatment…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy
Clinical trial registry entry evaluating MEK inhibitor–based combination therapy for KRAS G12R-altered pancreatic ductal adenocarcinoma. Rec…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors [EARLY_Phase 1]
An early-phase trial evaluating CDH17-targeted CAR-T cell therapy for advanced malignant solid tumors, including biliary tract cancer, color…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]
Phase 1 trial of Mesothelin-Specific T-Cells (FH-TCR-Tmesothelin) for metastatic pancreatic ductal adenocarcinoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers [Phase 1]
This Phase 1 trial update reports termination of the study evaluating BGB-3245 (brimarafenib) in combination with panitumumab for advanced o…
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma [Phase 2]
This Phase 2 trial of autologous tumor-infiltrating lymphocytes (MDA-TIL) in recurrent or refractory ovarian cancer, colorectal cancer, and …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Enfortumab Vedotin in Previously Treated Locally Advanced or Metastatic Pancreatic Cancer (EPIC) [Phase 2]
Phase 2 clinical trial of Enfortumab Vedotin in previously treated locally advanced or metastatic pancreatic cancer (EPIC) is active and not…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: PHL Treatment in Pancreatic Cancer [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating PHL treatment for pancreatic ductal adenocarcinoma is currently recruiting at Fox Chase Cancer Ce…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Short-course Versus Long-course Pre-operative Chemotherapy With mFOLFIRINOX or PAXG (CASSANDRA TRIAL) [Phase 3]
Phase 3 CASSANDRA trial compares short-course vs long-course preoperative chemotherapy with mFOLFIRINOX or PAXG in pancreatic ductal adenoca…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: A Phase 1B Study of Canakinumab, Spartalizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer (PC) Patients [Phase 1]
Phase 1B trial evaluating a quadruple combo of canakinumab, spartalizumab, nab-paclitaxel, and gemcitabine in metastatic pancreatic ductal a…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: A Study of mRNA Vaccines AK154 Monotherapy or in Combination With AK104/AK112,and Sequential mFOLFIRINOX in Surgically Resected PDAC [Phase 1]
Phase 1 clinical trial update evaluating AK154 as monotherapy or in combination with AK104/AK112, followed by sequential mFOLFIRINOX, in sur…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER) [Phase 1]
Phase 1 clinical trial SHAPER investigates losartan with hypofractionated radiotherapy after chemotherapy for Borderline Resectable or Local…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation [Phase 1, Phase 2]
An early-phase Phase 1/2a trial evaluating the combination of JAB-21822 and JAB-3312 in KRAS p.G12C-mutant advanced solid tumors, including …
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]
Phase 1 trial evaluating cobicistat in combination with gemcitabine and nab-paclitaxel in advanced or metastatic pancreatic ductal adenocarc…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Diagnostic Value of DWI-MRI for Detection of Peritoneal Metastases in High-risk Pancreatic Ductal Adenocarcinoma. [NA]
A completed clinical trial evaluated diffusion-weighted MRI (DWI-MRI) for detecting peritoneal metastases in patients with high-risk pancrea…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: AI-powered Early Detection for Pancreatic Cancer Via Non-contrast CT in Opportunistic Screening Cohort
Clinical trial update for an AI-powered non-contrast CT method to detect pancreatic cancer in opportunistic screening; the study is currentl…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: The LINFU® U.S. Registry for the Detection of Asymptomatic Pancreatic Ductal Adenocarcinoma
A registry trial update for the LINFU U.S. Registry aiming to detect asymptomatic pancreatic ductal adenocarcinoma; enrollment is by invitat…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Oncolytic Virotherapy Plus PD-1 Inhibitor and Lenvatinib for Patients With Advanced Pancreatic Cancer [Phase 1]
Phase 1 study evaluating a combination of oncolytic virotherapy, a PD-1 inhibitor, and lenvatinib in advanced pancreatic cancer has complete…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacy [Phase 1, Phase 2]
This clinical trial is evaluating the combination of durvalumab (anti-PD-L1) with rintatolimod (TLR-3 agonist) in metastatic pancreatic duct…