Pancreatic Ductal Adenocarcinoma

CLINICAL_TRIALS trial_result · 2025-06-05

Clinical Trial Update: Combined MEK, STAT3 and PD-1 Inhibition in Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]

This update reports completion of a Phase 1 trial evaluating a triple combination of MEK, STAT3, and PD-1 pathway inhibition in metastatic p…

CLINICAL_TRIALS trial_result · 2025-05-28

Clinical Trial Update: Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) [Phase 2]

Phase 2 study evaluating NIS793 with or without spartalizumab in combination with standard-of-care chemotherapy for first-line metastatic pa…

CLINICAL_TRIALS trial_result · 2025-05-22

Clinical Trial Update: DDP ip Combined With AG in PDAC With Peritoneal Metastasis [Phase 2]

This is a completed Phase 2 trial evaluating intraperitoneal cisplatin (DDP ip) combined with AG in pancreatic ductal adenocarcinoma with pe…

CLINICAL_TRIALS trial_result · 2025-05-21

Clinical Trial Update: Ketamine-assisted Therapy for Advanced GI Cancer [Phase 4]

Phase 4 trial evaluating ketamine-assisted therapy for advanced pancreatic ductal adenocarcinoma, focusing on cancer-related pain and demora…

CLINICAL_TRIALS trial_result · 2025-05-20

Clinical Trial Update: A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China [Phase 1]

The Phase 1 study of JAB-3312 in adults with advanced solid tumors in China has completed.

CLINICAL_TRIALS trial_result · 2025-05-20

Clinical Trial Update: Surgical Approach for Adenocarcinoma of the Pancreas With Synchronous Liver Metastases

This update describes a completed trial evaluating surgical approaches for pancreatic ductal adenocarcinoma with synchronous liver metastase…

CLINICAL_TRIALS trial_result · 2025-04-27

Clinical Trial Update: Clinical Validation of Immunovia Next-Generation Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer

This completed clinical trial validates Immunovia's next-generation blood biomarker test for detecting pancreatic cancer at early stages.

CLINICAL_TRIALS trial_result · 2025-04-25

Clinical Trial Update: AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma

A clinical trial sponsored by Roswell Park Cancer Institute is recruiting to evaluate an AI-derived biomarker to guide neoadjuvant treatment…

CLINICAL_TRIALS trial_result · 2025-04-20

Clinical Trial Update: Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]

Phase 1 trial of Mesothelin-Specific T-Cells (FH-TCR-Tmesothelin) for metastatic pancreatic ductal adenocarcinoma was terminated.

CLINICAL_TRIALS trial_result · 2025-04-20

Clinical Trial Update: A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers [Phase 1]

This Phase 1 trial update reports termination of the study evaluating BGB-3245 (brimarafenib) in combination with panitumumab for advanced o…

CLINICAL_TRIALS trial_result · 2025-04-17

Clinical Trial Update: Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma [Phase 2]

This Phase 2 trial of autologous tumor-infiltrating lymphocytes (MDA-TIL) in recurrent or refractory ovarian cancer, colorectal cancer, and …

CLINICAL_TRIALS trial_result · 2025-04-16

Clinical Trial Update: Enfortumab Vedotin in Previously Treated Locally Advanced or Metastatic Pancreatic Cancer (EPIC) [Phase 2]

Phase 2 clinical trial of Enfortumab Vedotin in previously treated locally advanced or metastatic pancreatic cancer (EPIC) is active and not…

CLINICAL_TRIALS trial_result · 2025-04-08

Clinical Trial Update: A Phase 1B Study of Canakinumab, Spartalizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer (PC) Patients [Phase 1]

Phase 1B trial evaluating a quadruple combo of canakinumab, spartalizumab, nab-paclitaxel, and gemcitabine in metastatic pancreatic ductal a…

CLINICAL_TRIALS trial_result · 2025-03-25

Clinical Trial Update: A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]

Phase 1 trial evaluating cobicistat in combination with gemcitabine and nab-paclitaxel in advanced or metastatic pancreatic ductal adenocarc…

CLINICAL_TRIALS trial_result · 2025-03-20

Clinical Trial Update: Diagnostic Value of DWI-MRI for Detection of Peritoneal Metastases in High-risk Pancreatic Ductal Adenocarcinoma. [NA]

A completed clinical trial evaluated diffusion-weighted MRI (DWI-MRI) for detecting peritoneal metastases in patients with high-risk pancrea…

CLINICAL_TRIALS trial_result · 2025-02-27

Clinical Trial Update: Oncolytic Virotherapy Plus PD-1 Inhibitor and Lenvatinib for Patients With Advanced Pancreatic Cancer [Phase 1]

Phase 1 study evaluating a combination of oncolytic virotherapy, a PD-1 inhibitor, and lenvatinib in advanced pancreatic cancer has complete…

CLINICAL_TRIALS trial_result · 2025-02-21

Clinical Trial Update: Study Evaluating the Ketogenic Diet in Patients With Metastatic Pancreatic Cancer [NA]

A clinical trial evaluating the ketogenic diet in patients with metastatic pancreatic ductal adenocarcinoma has completed.

CLINICAL_TRIALS trial_result · 2025-02-19

Clinical Trial Update: Pembrolizumab and CXCR4 Antagonist BL-8040 in Treating Patients With Metastatic Pancreatic Cancer [Phase 2]

A Phase 2 trial evaluating pembrolizumab with the CXCR4 antagonist BL-8040 in metastatic pancreatic cancer has completed, with results poste…

CLINICAL_TRIALS trial_result · 2025-02-14

Clinical Trial Update: Eryaspase With Modified FOLFIRINOX in Advanced Pancreatic Ductal Adenocarcinoma [Phase 1]

Georgetown University reported Phase 1 results for a trial of Eryaspase in combination with a modified FOLFIRINOX regimen in locally advance…

CLINICAL_TRIALS trial_result · 2025-02-07

Clinical Trial Update: Advances in Imaging to Assess Response in Pancreatic Cancer (AIR-PANC)

This clinical trial update covers AIR-PANC, an imaging-based study to assess treatment response in pancreatic ductal adenocarcinoma. The stu…

CLINICAL_TRIALS trial_result · 2025-01-28

Clinical Trial Update: Liposomal Irinotecan, S-1, and Oxaliplatin in Advanced Pancreatic Adenocarcinoma [Phase 1, Phase 2]

A completed Phase 1/2 trial evaluating a triplet regimen of liposomal irinotecan, S-1, and oxaliplatin in advanced pancreatic cancer (pancre…

CLINICAL_TRIALS trial_result · 2025-01-17

Clinical Trial Update: A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors [Phase 1]

Phase 1 study of ELI-002 in KRAS-mutated pancreatic ductal adenocarcinoma and other KRAS-driven solid tumors has completed enrollment, with …

CLINICAL_TRIALS trial_result · 2025-01-07

Clinical Trial Update: Study of Efficacy and Safety of NIS793 in Combination With Standard of Care (SOC) Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) - daNIS-2 [Phase 3]

Phase 3 trial daNIS-2 evaluating NIS793 in combination with standard-of-care chemotherapy for first-line metastatic pancreatic ductal adenoc…

CLINICAL_TRIALS trial_result · 2025-01-06

Clinical Trial Update: A Study to Assess YH003 in Combination with Toripalimab(anti-PD-1 MAb) Injection in Patients with Cancers [Phase 2]

Phase 2 study evaluating YH003 in combination with toripalimab in patients with melanoma and pancreatic ductal adenocarcinoma has completed.

CLINICAL_TRIALS trial_result · 2024-12-30

Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Treatment With NLM-001 and Standard Chemotherapy Plus Zalifrelimab in Patients With Advanced Pancreatic Cancer [Phase 1, Phase 2]

A Phase 1/2 clinical trial is evaluating NLM-001 in combination with standard chemotherapy and Zalifrelimab for advanced pancreatic ductal a…

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