Pancreatic Ductal Adenocarcinoma
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Reinforced Pancreaticojejunostomy With or Without glubran2 [Phase 2]
A Phase 2 clinical trial evaluating reinforced pancreaticojejunostomy with or without Glubran2 surgical adhesive in pancreatic and periampul…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Forecasting Occult liveR Metastasis Using an Exosomal Signature for Intelligent Guided Hepatic Targeting
The clinical trial evaluating an exosomal signature for predicting occult liver metastasis in pancreatic ductal adenocarcinoma has completed…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer [Phase 2]
Phase 2 clinical trial update evaluating combination chemotherapy before and after surgery for localized pancreatic cancer; results have bee…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway [Phase 1]
Phase 1 trial of DCC-3084 for MAPK-pathway driven advanced cancers has been terminated. The update notes the study status without presenting…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer [Phase 1]
A Phase 1 clinical trial evaluating STRO-004 in adults with refractory or recurrent metastatic cancer is currently recruiting, investigating…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer [Phase 2]
A Mayo Clinic–sponsored Phase 2 trial evaluating standard chemotherapy with or without stereotactic body radiation therapy for oligometastat…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC) [Phase 1, Phase 2]
An ongoing Phase 1/2 trial evaluating pancrelipase in metastatic pancreatic ductal adenocarcinoma. The study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]
This entry notes an ongoing Phase 1 trial evaluating an MK2 inhibitor in combination with mFOLFIRINOX for untreated metastatic pancreatic du…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Pancreatic Adenocarcinoma Signature Stratification for Treatment [Phase 2]
Phase 2 pancreatic cancer trial focusing on signature-based stratification for treatment. The study status is completed.
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy [Phase 2]
This is a phase 2 clinical trial update on pembrolizumab plus olaparib for metastatic pancreatic ductal adenocarcinoma with homologous recom…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Neo-adjuvant FOLF(IRIN)OX for Resectable Pancreatic Adenocarcinoma [Phase 2]
A Phase 2 study evaluating neoadjuvant FOLFIRINOX (FOLF(IRIN)OX) for patients with resectable pancreatic ductal adenocarcinoma has completed…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Study Investigating the Association of NP137 With mFOLFIRINOX in Locally Advanced Pancreatic Ductal Adenocarcinoma [Phase 1]
A Phase 1 trial evaluating NP137 in combination with mFOLFIRINOX for locally advanced pancreatic ductal adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Study of Pembrolizumab With or Without Defactinib Following Chemotherapy as a Neoadjuvant and Adjuvant Treatment for Resectable Pancreatic Ductal Adenocarcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab with or without defactinib after chemotherapy as neoadjuvant and adjuvant therapy for resectable panc…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer [Phase 4]
Phase 4 clinical trial evaluating hepatic artery chemotherapy for patients with localized pancreatic ductal adenocarcinoma; the study is act…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers [Phase 2]
Phase 2 study evaluating the PET imaging agent [18F]FAPI-74 in gastrointestinal cancers has completed.
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma [Phase 2]
Phase 2 clinical trial evaluating the [68Ga]FAPI-46 PET imaging tracer in pancreatic ductal adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma [NA]
Completed clinical trial investigating the relationship between organochlorine concentration in adipose tissue and pancreatic ductal adenoca…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Mesenchymal CTC Ratio Dynamics Predicts Response and Survival in Pancreatic Ductal Adenocarcinoma With Neoadjuvant/Conversion Therapy
A completed study in pancreatic ductal adenocarcinoma shows that the dynamics of mesenchymal circulating tumor cell ratios during neoadjuvan…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Promitil Treatment of Patients With Solid Tumors Associated With Deleterious Mutations Who Have Progressed After Therapy [Phase 2]
Phase 2 clinical trial evaluating Promitil in patients with solid tumors carrying deleterious mutations that progressed after prior therapy …
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of JAB-3312 in adults with advanced solid tumors has been completed, evaluating multiple tumor indications.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors. [Phase 1]
A Phase I study of [177Lu]Lu-FF58 in patients with advanced solid tumors was terminated. The sponsor was Novartis Pharmaceuticals, and the t…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted Therapy [Phase 1]
A completed Phase 1 trial assessing a CCR2-targeted PET imaging agent to visualize pancreatic tumors and predict response to standard treatm…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 trial assessing Onvansertib in combination with nanoliposomal irinotecan, leucovorin, and fluorouracil for second-line metastatic …
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) [Phase 3]
Phase 3 study of Daraxonrasib (RMC-6236) for previously treated metastatic pancreatic ductal adenocarcinoma is active but not currently recr…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Escitalopram to Placebo in Patients With Localized Pancreatic Cancer [Phase 2]
Phase 2 randomized trial comparing escitalopram to placebo in localized pancreatic cancer was terminated; results have been posted.