Pancreatic Ductal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: PANORAMIX : Optimizing 1st-line NALIRIFOX and Exploring Microbiota's Role in 2nd Line Pancreatic Cancer Treatment [Phase 2]
This is a Phase 2 clinical trial update for PANORAMIX, examining optimization of first-line NALIRIFOX (liposomal irinotecan-based therapy) a…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Icaritin in Combination With AG in Patients With Previously Untreated Advanced Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial is evaluating Icaritin in combination with AG for previously untreated advanced pancreatic ductal adenocarcinoma an…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Prospective Cohort of Patients Treated Using Neoadjuvant Modified FOLFIRINOX 6 Cycles for Potentially Resectable Pancreatic Duct Adenocarcinoma, Candidate for Participation in the PANACHE02 Clinical Trial
Prospective cohort in Rouen evaluating six cycles of neoadjuvant modified FOLFIRINOX for potentially resectable pancreatic ductal adenocarci…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Predictive Risk Factors for Pancreatic Fistula After Pancreaticoduodenectomy [NA]
Ongoing clinical trial assessing predictive risk factors for pancreatic fistula after pancreaticoduodenectomy in patients with pancreatic or…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: A Study of DCTY1102 Injection in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of DCTY1102 Injection in patients with advanced solid tumors, including pancreatic ductal adenocarcinoma, colorectal cancer, n…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Therapeutic Study of 177Lu-CTR-FAPI in Advanced Metastatic Digestive Malignancies [NA]
Clinical trial update for 177Lu-CTR-FAPI in advanced metastatic digestive cancers; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC) [Phase 2]
Phase 2 clinical trial evaluating the combination of nalirifoX (nanoliposomal irinotecan) with radiation therapy for pancreatic ductal adeno…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]
A Phase 1 clinical trial update describing the safety/tolerability study of SX-682 with nivolumab as maintenance therapy for metastatic panc…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals [EARLY_Phase 1]
This early-phase screening trial is evaluating prospective screening for pancreatic ductal adenocarcinoma in individuals at high risk.
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: EUS-RFA PANCARDINAL-1 Trial [Phase 2]
Phase 2 trial update on endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for pancreatic ductal adenocarcinoma is currently rec…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery [NA]
This clinical trial aims to evaluate high-volume washing of the abdomen during surgery to improve survival in patients with resectable pancr…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Selective Plasma Adsorption of Extracellular DNA in Prevention of Intraoperative Metastasis in Pancreatic Cancer (Pilot Study) [NA]
Pilot clinical trial update on selective plasma adsorption of extracellular DNA to prevent intraoperative metastasis in pancreatic ductal ad…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Clinical Study of Lewis Antigen Assay Combined With CA19-9 Assay to Assess Prognosis in Patients With Pancreatic Cancer [NA]
This clinical study is evaluating a Lewis antigen assay combined with CA19-9 to assess prognosis in pancreatic cancer (pancreatic ductal ade…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial is evaluating Tumor Treating Fields EF-39 in combination with atezolizumab, gemcitabine, and nab-paclitaxel as firs…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy
Clinical trial registry entry evaluating MEK inhibitor–based combination therapy for KRAS G12R-altered pancreatic ductal adenocarcinoma. Rec…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors [EARLY_Phase 1]
An early-phase trial evaluating CDH17-targeted CAR-T cell therapy for advanced malignant solid tumors, including biliary tract cancer, color…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: PHL Treatment in Pancreatic Cancer [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating PHL treatment for pancreatic ductal adenocarcinoma is currently recruiting at Fox Chase Cancer Ce…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Short-course Versus Long-course Pre-operative Chemotherapy With mFOLFIRINOX or PAXG (CASSANDRA TRIAL) [Phase 3]
Phase 3 CASSANDRA trial compares short-course vs long-course preoperative chemotherapy with mFOLFIRINOX or PAXG in pancreatic ductal adenoca…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: A Study of mRNA Vaccines AK154 Monotherapy or in Combination With AK104/AK112,and Sequential mFOLFIRINOX in Surgically Resected PDAC [Phase 1]
Phase 1 clinical trial update evaluating AK154 as monotherapy or in combination with AK104/AK112, followed by sequential mFOLFIRINOX, in sur…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER) [Phase 1]
Phase 1 clinical trial SHAPER investigates losartan with hypofractionated radiotherapy after chemotherapy for Borderline Resectable or Local…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation [Phase 1, Phase 2]
An early-phase Phase 1/2a trial evaluating the combination of JAB-21822 and JAB-3312 in KRAS p.G12C-mutant advanced solid tumors, including …
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: AI-powered Early Detection for Pancreatic Cancer Via Non-contrast CT in Opportunistic Screening Cohort
Clinical trial update for an AI-powered non-contrast CT method to detect pancreatic cancer in opportunistic screening; the study is currentl…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: The LINFU® U.S. Registry for the Detection of Asymptomatic Pancreatic Ductal Adenocarcinoma
A registry trial update for the LINFU U.S. Registry aiming to detect asymptomatic pancreatic ductal adenocarcinoma; enrollment is by invitat…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacy [Phase 1, Phase 2]
This clinical trial is evaluating the combination of durvalumab (anti-PD-L1) with rintatolimod (TLR-3 agonist) in metastatic pancreatic duct…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Using Tumor Models to Determine Treatments [Phase 2]
Phase 2 clinical trial at University Health Network uses tumor models to guide treatment choices for pancreatic ductal adenocarcinoma and ot…