Pancreatic Ductal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types [Phase 2, Phase 3]
A multicenter validation trial evaluating the PET imaging agent [18F]AlF-FAPI-74 to visualize cancer-associated fibroblasts across esophagea…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: A Study Evaluating the Efficacy of 5-FU + NALIRI and 5-FU + NALIRINOX for PDAC (NALPAC) [Phase 2]
Phase 2 study evaluating two regimens in metastatic pancreatic ductal adenocarcinoma: 5-Fluorouracil with nanoliposomal irinotecan (nal-IRI)…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: ACCENT: AMP945 in Combination with Nab-paclitaxel and Gemcitabine for Treatment of Pancreatic Cancer [Phase 1, Phase 2]
Clinical trial ACCENT is evaluating AMP945 in combination with nab-paclitaxel and gemcitabine for pancreatic cancer in Phase 1/2; the study …
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 MAb, Administered Alone and in Combination with a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study) [Phase 1, Phase 2]
Phase 1/2 MORNINGSTAR trial evaluating mavrostobart (PT199), an anti-CD73 antibody, alone or with a PD-1 inhibitor or chemotherapy in non-sm…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC) [Phase 1]
This Phase 1 clinical trial update describes CHASe-PDAC, a study of chemotherapy plus stool transplantation for unresectable or metastatic a…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of surufatinib and camrelizumab with AS as first-line therapy for advanced metastatic …
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Adjuvant Trial in Patients With Resected PDAC Randomized to Allocation of Oxaliplatin- or Gemcitabine-based Chemotherapy by Standard Clinical Criteria or by a Transcriptomic Treatment Specific Stratification Signature [Phase 3]
Phase 3 adjuvant trial comparing oxaliplatin- versus gemcitabine-based chemotherapy for resected pancreatic ductal adenocarcinoma, with trea…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: AG Combined With Cadonilimab Sequential Short-course Radiotherapy in the Treatment of Locally aPDAC [Phase 2]
Phase 2 clinical trial evaluating AG in combination with Cadonilimab and sequential short-course radiotherapy for locally advanced pancreati…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial is evaluating nab-paclitaxel and gemcitabine with or without SBP-101 in metastatic pancreatic ductal adenocarcino…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: A Study to Determine the Effect of CT3001 in Patients with Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of CT3001 in adults with advanced solid tumors is currently recruiting, including colorectal cancer and pancreatic ductal …
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers [Phase 1]
This document reports a Phase 1 clinical trial of NI-1801 for mesothelin-expressing solid cancers, with recruiting status and multiple indic…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Profiling the Intratumoral Microbiome of Pancreatic Ductal Adenocarcinoma Based on EUS-FNB Tissue Samples and Exploring Its Impact on Tumor Diagnosis and Prognosis.
This clinical trial is profiling the intratumoral microbiome of pancreatic ductal adenocarcinoma using EUS-FNB tissue and exploring how micr…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: The ASCEND Study: Gemcitabine and Nab-Paclitaxel With LSTA1 (Certepetide) or Placebo in Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
Phase 2 ASCEND trial evaluating gemcitabine and nab-paclitaxel with LSTA1 (certepetide) versus placebo in untreated metastatic pancreatic du…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Pancreatic Cancer Screening Through the Detection of Elastase-1 Combined With Other Examinations
A clinical trial is actively recruiting to evaluate pancreatic cancer screening using elastase-1 detection in combination with other examina…
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: High Resolution Ultrasound in Pancreatic Ductal Adenocarcinoma [NA]
A clinical trial update from University Health Network evaluating high-resolution ultrasound in pancreatic ductal adenocarcinoma; the study …
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Innovative Therapeutic Treatments to Inhibit Perineural Invasion in Pancreatic Adenocarcinoma
A clinical trial is exploring innovative therapies to inhibit perineural invasion in pancreatic ductal adenocarcinoma and is not yet recruit…
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CLINICAL_TRIALS research · 2024-10-02Clinical Trial Update: Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1/2 evaluation of NGM707 as a monotherapy and in combination with pembrolizumab in advanc…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001) [Phase 2]
Phase 2 trial ALTER-PA-001 is evaluating a combination of Anlotinib, Benmelstobart, and AG as first-line therapy for advanced metastatic pan…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: AB122 Platform Study [Phase 1]
Phase 1 AB122 platform study is currently recruiting for advanced or metastatic solid tumors, including pancreatic ductal adenocarcinoma and…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Recurrent Disease Detection After Resection of Pancreatic Adenocarcinoma Using a Standardized Surveillance Strategy [NA]
This clinical trial update describes ongoing enrollment for a study evaluating a standardized surveillance strategy to detect recurrent dise…
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CLINICAL_TRIALS research · 2024-09-04Clinical Trial Update: A Study of CEND-1 With Chemotherapy as First-Line Therapy in Patients With Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating CEND-1 in combination with chemotherapy as first-line therapy for pancreatic ductal adenocarcinoma is cu…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer [Phase 3]
A Phase 3 trial evaluating perioperative or adjuvant mFOLFIRINOX for resectable pancreatic cancer is currently recruiting.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Radiotherapy With Sequential Chemotherapy Combined With PD-1 Inhibitor and Thymalfasin for BRPC [Phase 2]
Phase 2 clinical trial evaluating radiotherapy with sequential chemotherapy plus a PD-1 inhibitor and thymalfasin for borderline resectable …
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer [Phase 2, Phase 3]
Clinical trial update on OT-101 in combination with mFOLFIRINOX for advanced, unresectable, or metastatic pancreatic ductal adenocarcinoma; …
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: The LINFU® U.S. Registry for the in the General Population Without Risk Factors
A clinical trial registry update from Adenocyte, LLC about the LINFU U.S. Registry; the study (NCT06276803) is not yet recruiting and involv…