Pancreatic Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Conversion Surgery Vs. Palliative Care in Pancreatic Cancer Oligometastatic to the Liver [Phase 2]
A Phase 2 clinical trial compares conversion surgery to palliative care for pancreatic cancer with liver oligometastases and is currently re…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: A Multi-center, Single-arm, Prospective Non-interventional Study to Investigate the Safety Profiles and Effectiveness of Liposomal Irinotecan (ONIVYDE®) in Combination with 5-fluorouracil (5-FU) and Leucovorin (LV) in Chinese Patients with Metastatic Pancreatic Cancer As Approval Condition (SEOPAC)
This is a multi-center, single-arm, prospective non-interventional study to evaluate the safety and effectiveness of liposomal irinotecan (O…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancer [Phase 1]
This is a Phase 1 open-label study evaluating ONO-7913 and ONO-4538 in combination with modified FOLFIRINOX as first-line therapy for metast…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Radiation Therapy (RT) and Chemotherapy for the Treatment of Pancreatic Cancer with Homologous Recombination Deficiency That Has Spread to the Liver [Phase 1]
This Phase 1 study evaluates the combination of radiation therapy and chemotherapy for pancreatic cancer with homologous recombination defic…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas [Phase 2]
Phase 2 trial of ganitumab in locally advanced unresectable pancreatic cancer has been terminated; results were posted on 2024-11-08.
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Irreversible Electroporation Ablation Combined With Anti-PD(L)1 Therapy for Locally Advanced Pancreatic Cancer
This clinical trial evaluates irreversible electroporation ablation combined with anti-PD-L1 therapy for locally advanced pancreatic cancer;…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: A Randomized Phase 2/3 Multi-Center Study of SM-88 in Participants With Metastatic Pancreatic Cancer [Phase 2, Phase 3]
A randomized Phase 2/3 multi-center trial of SM-88 for metastatic pancreatic cancer was terminated, with results posted on 2024-11-06.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic Cancer [Phase 3]
A Phase 3 neoadjuvant trial evaluating pamrevlumab in combination with chemotherapy (gemcitabine plus nab-paclitaxel or FOLFIRINOX) for loca…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: An Observational Study to Learn More About the Impact of Gadoxetate Sodium-Enhanced Magnetic Resonance Imaging (EOB-MRI) When Used to Diagnose the Spread of Cancer From the Pancreas to the Liver in Japanese People Under Real-World Conditions
A completed observational study in Japan evaluated the real-world use of gadoxetate disodium-enhanced MRI (EOB-MRI) to diagnose metastatic s…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus NALIRIFOX as Conversion Therapy of Locally Advanced Pancreatic Cancer [Phase 2]
A Phase 2 clinical trial update evaluating NALIRIFOX combined with a PD-1 inhibitor and sequential radiotherapy versus NALIRIFOX alone as co…
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CLINICAL_TRIALS research · 2024-10-31Clinical Trial Update: Nimotuzumab Combined With mFOLFIRINOX/GX as Postoperative Adjuvant Therapy in Pancreatic Cancer [Phase 2]
A Phase 2 clinical trial evaluating nimotuzumab in combination with modified FOLFIRINOX/GX as postoperative adjuvant therapy for pancreatic …
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: YL-13027 and/or HY-0102 Combined With AG Regimen Chemotherapy for Metastatic Pancreatic Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating YL-13027 and HY-0102 in combination with AG regimen chemotherapy for metas…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors [Phase 1]
Phase 1 trial of CCT301-59 CAR T therapy in adults with recurrent or refractory solid tumors has been terminated. The study included soft ti…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas [NA]
This entry reports a clinical trial assessing preoperative optimization of modifiable risk factors to reduce postoperative complications in …
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Fecal and Oral Microbiota Between Pancreatic Cancer and Benign/Low-grade Malignant Tumor Patients
A completed clinical trial comparing fecal and oral microbiota profiles between pancreatic cancer patients and those with benign or low-grad…
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CLINICAL_TRIALS withdrawal · 2024-10-26Clinical Trial Update: An Exercise and Nutrition Monitoring Intervention (Pt Pal) for the Improvement of Strength in Patients With Pancreatic or Stomach Cancer Receiving Chemoradiation Therapy Before Surgery, SurgeryStrong Study [NA]
A clinical trial evaluating an exercise and nutrition monitoring intervention for strengthening patients with gastric or pancreatic cancer u…
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CLINICAL_TRIALS withdrawal · 2024-10-26Clinical Trial Update: Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver [Phase 1, Phase 2]
The clinical trial NCT05610826 comparing preoperative PRRT to surgical cytoreduction for metastatic pancreatic neuroendocrine tumors to the …
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery [Phase 3]
Phase 3 trial updates evaluate gemcitabine with or without erlotinib followed by the same regimen with or without radiation therapy and cape…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Profiling the Intratumoral Microbiome of Pancreatic Ductal Adenocarcinoma Based on EUS-FNB Tissue Samples and Exploring Its Impact on Tumor Diagnosis and Prognosis.
This clinical trial is profiling the intratumoral microbiome of pancreatic ductal adenocarcinoma using EUS-FNB tissue and exploring how micr…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer [Phase 1]
First-in-human Phase 1 trial of TORL-2-307-MAB in participants with advanced cancer, including gastric cancer, pancreatic cancer, and gastro…
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CLINICAL_TRIALS research · 2024-10-21Clinical Trial Update: Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial [Phase 3]
A Phase 3 trial (IRIS-trial) is evaluating iron administration to improve recovery after surgery with blood loss and is currently recruiting…
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CLINICAL_TRIALS research · 2024-10-21Clinical Trial Update: Standard Versus Prolonged Antibiotic Prophylaxis After Pancreatoduodenectomy (SPARROW) [Phase 4]
The SPARROW trial compares standard versus prolonged antibiotic prophylaxis after pancreatoduodenectomy for pancreatic cancer and is current…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Olaparib and Durvalumab (MEDI4736) in Patients with Metastatic Pancreatic Cancer and DNA Damage Repair Genes Alterations [Phase 2]
Phase 2 clinical trial evaluating olaparib in combination with durvalumab for metastatic pancreatic cancer with DNA damage repair gene alter…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Evaluation, in Humans, of the Correlation Between Hepatotoxicity, Neurotoxicity Induced by Oxaliplatin, and Blood Levels of HMGB1 [NA]
This clinical trial evaluates whether hepatotoxicity and neurotoxicity from oxaliplatin correlate with blood levels of HMGB1 in patients wit…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: QUILT-2.019: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer [Phase 1, Phase 2]
Clinical trial update for QUILT-2.019, a Phase 1/2 study of AMG-655 or AMG-479 with gemcitabine for metastatic pancreatic cancer, with resul…