Pancreatic Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
A clinical trial update investigating pre- and post-operative thromboelastography (TEG) indices in patients undergoing surgical resection, c…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Study of HuMab-5B1 (MVT-5873) in Subjects With Pancreatic Cancer or Other Cancer Antigen 19-9 (CA19-9) Positive Malignancies [Phase 1]
A Phase 1 study of HuMab-5B1 (MVT-5873) in CA19-9 positive malignancies, including pancreatic cancer, has been terminated.
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma [Phase 2]
A Phase 2 clinical trial update evaluating mFOLFIRINOX with or without stereotactic body radiotherapy for locally advanced, non-resectable p…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS withdrawal · 2025-01-24Clinical Trial Update: Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers [Phase 1]
Phase 1 trial evaluating the combination of RMC-4630 and LY3214996 in metastatic KRAS-mutant cancers has been terminated. The study encompas…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: CPI-613 in Combination With Modified FOLFIRINOX in Locally Advanced Pancreatic Cancer [Phase 1, Phase 2]
This update reports completed Phase 1 and Phase 2 arms of a study evaluating CPI-613 in combination with a modified FOLFIRINOX regimen in lo…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian Cancer [Phase 1]
A Phase 1 trial from the University of Michigan evaluates talazoparib in combination with belinostat in metastatic breast cancer, metastatic…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Using Catumaxomab/Catuvab Device [NA]
A completed validation trial evaluated removal of EpCAM-positive tumor cells from blood collected during tumor surgery using the Catumaxomab…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CBX-12 in adults with advanced or metastatic refractory solid tumors. The trial includes multiple cancer types and is cur…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Structured Follow-up Intervention on Glucose Status After Pancreatic Cancer Surgery [NA]
A clinical trial update describing a structured follow-up intervention to assess glucose status after pancreatic cancer surgery. The study i…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Neoadjuvant/Adjuvant Sintilimab, Nab-paclitaxel, and Gemcitabine for Resectable/Borderline Resectable Pancreatic Cancer [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant/adjuvant therapy with sintilimab (PD-1 inhibitor) plus nab-paclitaxel and gemcitabine for rese…
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CLINICAL_TRIALS other · 2025-01-21Clinical Trial Update: A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab [Phase 1, Phase 2]
A Phase 1/2 study of evofosfamide in combination with zalifrelimab and balstilimab is currently recruiting for metastatic prostate cancer, m…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Liposomal Irinotecan + Oxaliplatin + Bevacizumab Versus Liposomal Irinotecan + 5-FU/LV [Phase 1, Phase 2]
A Phase 1/2 trial evaluating liposomal irinotecan with oxaliplatin and bevacizumab versus liposomal irinotecan with 5-FU/leucovorin in advan…
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CLINICAL_TRIALS approval · 2025-01-17Clinical Trial Update: Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation
Eli Lilly's RET inhibitor selpercatinib (Retevmo) has been approved for marketing to treat cancers driven by RET activation, including non-s…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Role of Exosomes in Pancreatic Cancer Progression
A clinical trial is investigating the role of exosomes in pancreatic cancer progression and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients with Pancreatic Cancer [EARLY_Phase 1]
An early-phase trial evaluated neoadjuvant chemotherapy and radiation therapy followed by gemcitabine in patients with pancreatic cancer, an…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Bortezomib combined with a PD-1 monoclonal antibody and the MFOLFIRINOX regimen for metastatic pancreati…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Adebrelimab Combined With Irinotecan Liposomal (II), Oxaliplatin, and 5-FU/LV Conversion Therapy for Locally Advanced Pancreatic Cancer [Phase 2]
Phase 2 trial evaluating adebrelimab in combination with liposomal irinotecan, oxaliplatin, and 5-FU/leucovorin conversion therapy for local…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Assessing Pancreatic Fistula Rates After Distal Pancreatectomy Using AEON Endostapler
An ongoing clinical trial at University Hospital Heidelberg is evaluating pancreatic fistula rates after distal pancreatectomy using the AEO…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: In This Study, a Retrospective Analysis Was Conducted to Explore the Risk Factors for Patients Undergoing Pancreaticoduodenal Surgery (PD) to Achieve TO, and a Nomogram Prediction Model Was Further Established to Promote the Standardization and Standardization of PD Surgical Quality Evaluation.
A retrospective study examined risk factors in patients undergoing pancreaticoduodenectomy and developed a nomogram to standardize PD surgic…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers [Phase 1, Phase 2]
This is an update on Claudin18.2-targeted CAR-T therapy CT041 for gastric and pancreatic cancers (and related digestive cancers), showing ph…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: TAS102 in Combination With NAL-IRI in Advanced GI Cancers [Phase 1, Phase 2]
This document provides an update on an ongoing Phase 1/2 clinical trial evaluating the combination of TAS-102 with nanoliposomal irinotecan …
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: mFOLFIRINOX Plus Anlotinib and Sintilimab for Advanced Pancreatic Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a combination of mFOLFIRINOX, Anlotinib, and Sintilimab for locally advanced or metastatic pancreatic …
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: PREVENPANC Project: a Spanish Multicenter Study for Pancreatic Cancer Prevention
This clinical trial update describes the PREVENPANC project, a Spanish multicenter study aimed at pancreatic cancer prevention, which is not…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 is Administered in Combination With IV Modified FOLFIRINOX (mFFX) With or Without IV Budigalimab Compared to mFFX in Adult Participants With Untreated Pancreatic Cancer Metastasis [Phase 1]
A Phase 1 trial evaluating safety and changes in disease activity when ABBV-927 is infused with modified FOLFIRINOX, with or without budigal…