Pancreatic Cancer

• CLINICAL_TRIALS withdrawal · 2025-07-30
  Clinical Trial Update: HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

  Alaunos Therapeutics reports termination of a Phase I/II autologous TCR-T cell trial across several solid tumors. The study focused on HLA t…

• CLINICAL_TRIALS research · 2025-07-30
  Clinical Trial Update: A Single-center, Prospective, Two Cohort Study of Surufatinib Combined With AG or AG in the First-line Treatment of Locally Advanced or Metastatic Pancreatic Cancer [Phase 2]

  This is a Phase 2, single-center prospective study evaluating surufatinib in combination with AG regimen as first-line therapy for locally a…

• CLINICAL_TRIALS trial_result · 2025-07-29
  Clinical Trial Update: INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancer [Phase 2]

  Phase 2 trial update for INCMGA00012 in previously treated unresectable or metastatic adenosquamous pancreatic or ampullary cancer (NCT04116…

• CLINICAL_TRIALS trial_result · 2025-07-29
  Clinical Trial Update: Multivisceral Oncological Resections Involving the Pancreas - An International Multicenter Study

  This document reports the completion of an international multicenter trial evaluating multivisceral oncological resections involving the pan…

• CLINICAL_TRIALS research · 2025-07-29
  Clinical Trial Update: Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer [Phase 2]

  Phase 2 clinical trial evaluating medical cannabis in patients with advanced pancreatic cancer (non-resectable or metastatic) and metastatic…

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• CLINICAL_TRIALS research · 2025-07-29
  Clinical Trial Update: EUS-guided Choledochoduodenostomy vs ERCP as First Line in Malignant Distal Obstruction (CARPEDIEM Trial) [NA]

  A clinical trial comparing EUS-guided choledochoduodenostomy versus ERCP as first-line treatment for malignant distal biliary obstruction is…

• CLINICAL_TRIALS research · 2025-07-28
  Clinical Trial Update: ExoLuminate Study for Early Detection of Pancreatic Cancer

  The ExoLuminate Study, sponsored by Biological Dynamics, is currently recruiting to evaluate exosome-based biomarkers for the early detectio…

• CLINICAL_TRIALS research · 2025-07-25
  Clinical Trial Update: OSE2101+FOLFIRI, or FOLFIRI Maintenance After FOLFIRINOX-based Induction Therapy in Advanced or Metastatic PDAC [Phase 2]

  This entry describes a Phase 2 trial evaluating OSE2101 with FOLFIRI, or FOLFIRI maintenance after FOLFIRINOX induction, in advanced or meta…

• CLINICAL_TRIALS research · 2025-07-25
  Clinical Trial Update: Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer [Phase 1]

  A Phase 1 clinical trial is evaluating intra-tumoral Mitazalimab (CD40 antibody) in combination with irreversible electroporation for locall…

• CLINICAL_TRIALS trial_result · 2025-07-25
  Clinical Trial Update: A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer [Phase 1, Phase 2]

  Phase 1/2 study evaluating hydroxychloroquine in combination with gemcitabine and Abraxane in pancreatic cancer has completed.

• CLINICAL_TRIALS research · 2025-07-25
  Clinical Trial Update: Influence of Metastatic Sites on Survival Outcomes and Predictive Factors for Extended Survival in Metastatic Pancreatic Cancer a Retrospective Study

  A retrospective study from Assiut University investigates how metastatic sites influence survival in metastatic pancreatic cancer and identi…

• CLINICAL_TRIALS research · 2025-07-25
  Clinical Trial Update: Use Of Indocyanine Green In Pancreas Surgery

  A clinical trial is evaluating the use of indocyanine green to assist pancreatic cancer surgery and is currently recruiting.

• CLINICAL_TRIALS research · 2025-07-25
  Clinical Trial Update: Pancreatic Cancer Registry: For Any Person With a Personal or Family History

  A Johns Hopkins University–sponsored pancreatic cancer registry trial is currently recruiting, enrolling individuals with a personal or fami…

• CLINICAL_TRIALS withdrawal · 2025-07-25
  Clinical Trial Update: Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patients [Phase 1]

  A Phase Ib trial evaluating the KRAS G12C inhibitor adagrasib in KRAS G12C mutant metastatic pancreatic cancer has been withdrawn.

• CLINICAL_TRIALS research · 2025-07-24
  Clinical Trial Update: Characteristics of Intestinal Microbiome Following Pancreatic Surgery

  A clinical trial is researching how the intestinal microbiome changes after pancreatic surgery in patients with pancreatic cancer; recruitme…

• CLINICAL_TRIALS research · 2025-07-24
  Clinical Trial Update: A Study of the Life Changes Experienced by Patients With Pancreatic Cancer

  This clinical trial update describes an ongoing study examining the life changes experienced by patients with pancreatic cancer.

• CLINICAL_TRIALS research · 2025-07-23
  Clinical Trial Update: A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer [Phase 2]

  This is a Phase 2 neoadjuvant trial evaluating the combination of tislelizumab and SX-682 for resectable pancreatic cancer; the study is cur…

• CLINICAL_TRIALS research · 2025-07-23
  Clinical Trial Update: Expanded Access Protocol for the Use of SL-28 in the Treatment of Advanced Solid Tumors

  This clinical trials update describes an expanded access protocol for SL-28 in patients with advanced solid tumors and lists eligible condit…

• CLINICAL_TRIALS research · 2025-07-23
  Clinical Trial Update: Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients [NA]

  This clinical trial is evaluating acupuncture to address oxaliplatin-induced peripheral neuropathy in patients with gastrointestinal cancers…

• CLINICAL_TRIALS research · 2025-07-22
  Clinical Trial Update: Sintilimab Combined With Chemotherapy and Radiotherapy in Patients With Inoperable Pancreatic Cancer [Phase 2]

  A Phase 2 clinical trial is evaluating sintilimab in combination with chemotherapy and radiotherapy for patients with inoperable pancreatic …

• CLINICAL_TRIALS trial_result · 2025-07-20
  Clinical Trial Update: Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies [Phase 1]

  This Phase 1 study of NP-G2-044, a metastasis inhibitor, in patients with advanced or metastatic treatment-refractory solid tumors has compl…

• CLINICAL_TRIALS trial_result · 2025-07-18
  Clinical Trial Update: Study of Stereotactic Body Radiation Therapy in Patients With Intact Pancreatic Cancer [Phase 1, Phase 2]

  This clinical trial update reports results from a Phase 1/2 study evaluating stereotactic body radiation therapy for pancreatic cancer; the …

• CLINICAL_TRIALS research · 2025-07-18
  Clinical Trial Update: Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma [Phase 1]

  Phase 1 clinical trial evaluating intraoperative radiation therapy after stereotactic body radiation therapy and chemotherapy for pancreatic…

• CLINICAL_TRIALS trial_result · 2025-07-18
  Clinical Trial Update: A Study Comparing Restrictive and Liberal Fluid Therapy During Pancreatecoduodenectomy Surgery [NA]

  This update reports the completion of a clinical trial comparing restrictive versus liberal fluid therapy during pancreaticoduodenectomy for…

• CLINICAL_TRIALS trial_result · 2025-07-18
  Clinical Trial Update: TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma [Phase 2]

  Phase 2 clinical trial update from The University of Hong Kong evaluating TAS-102 in advanced, refractory pancreatic adenocarcinoma; the stu…