Pancreatic Cancer

• CLINICAL_TRIALS research · 2025-11-21
  Clinical Trial Update: Austrian Registry for Evaluation of Treatment Patterns and Outcome in Patients With Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

  A registry-based study in Austria is recruiting to evaluate treatment patterns and outcomes in patients with advanced pancreatic ductal aden…

• CLINICAL_TRIALS research · 2025-11-21
  Clinical Trial Update: Study on Efficacy and Safety of VMAT Technique With Local Dose Escalation for Unresectable Pancreatic Cancer

  A clinical trial evaluating volumetric modulated arc therapy (VMAT) with local dose escalation for unresectable pancreatic cancer; the study…

• EMA approval · 2025-11-20
  EMA Authorised: Afinitor (everolimus) — Novartis Europharm Limited

  EMA authorised Afinitor (everolimus) for renal cell carcinoma, breast cancer and pancreatic neoplasms. The marketing authorisation holder is…

• CLINICAL_TRIALS research · 2025-11-19
  Clinical Trial Update: Firstline Sequential AG and mFOLFOX Combined With Serplulimab and Bevacizumab Versus AG Chemotherapy Alone in Advanced Pancreatic Cancer [Phase 3]

  A Phase 3 clinical trial is recruiting to evaluate first-line sequential AG and mFOLFOX with serplulimab and bevacizumab versus AG chemother…

• CLINICAL_TRIALS trial_result · 2025-11-19
  Clinical Trial Update: Cabozantinib and Pembrolizumab in Metastatic Pancreas [Phase 2]

  A Phase 2 trial evaluating the combination of cabozantinib and pembrolizumab in metastatic pancreatic cancer has completed, with results pos…

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• CLINICAL_TRIALS trial_result · 2025-11-19
  Clinical Trial Update: High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies [NA]

  A clinical trial is evaluating high dose-rate brachytherapy for unresectable primary and metastatic liver malignancies. The study is current…

• CLINICAL_TRIALS research · 2025-11-19
  Clinical Trial Update: Pancreatic Adenocarcinoma Gene Environment Risk Study

  This clinical trial is currently recruiting to examine gene-environment risk factors for pancreatic cancer (pancreatic adenocarcinoma).

• CLINICAL_TRIALS research · 2025-11-18
  Clinical Trial Update: GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites [Phase 1, Phase 2]

  This is a Phase 1/Phase 2 clinical trial update for GAIA-102 delivered intraperitoneally in patients with advanced microsatellite-stable gas…

• CLINICAL_TRIALS withdrawal · 2025-11-18
  Clinical Trial Update: FOLFIRINOX + NIS793 in Pancreatic Cancer [Phase 1]

  A Phase 1 trial evaluating the combination of FOLFIRINOX and NIS793 in pancreatic cancer has been terminated.

• CLINICAL_TRIALS research · 2025-11-18
  Clinical Trial Update: HRS 4642 Injection Combined With AG Versus Placebo Combined With AG Therapy in First-Line Advanced or Metastatic Pancreatic Cancer [Phase 3]

  Phase 3 trial evaluating HRS 4642 injection plus AG therapy versus placebo plus AG therapy as first-line treatment for KRAS G12D-mutant adva…

• CLINICAL_TRIALS research · 2025-11-18
  Clinical Trial Update: Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer [Phase 2]

  A Phase 2 trial evaluating adebrelimab in combination with chemotherapy as neoadjuvant therapy for resectable pancreatic cancer is not yet r…

• CLINICAL_TRIALS research · 2025-11-18
  Clinical Trial Update: Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery [NA]

  A clinical trial is evaluating whether adding magnetic resonance imaging improves selection of pancreatic cancer patients for surgery; the s…

• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) [Phase 2]

  Phase 2 trial evaluating pembrolizumab plus lenvatinib in previously treated patients with select solid tumors; results on efficacy and safe…

• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: Anamorelin Study for Advanced Pancreatic Cancer [Phase 2]

  Phase 2 trial of anamorelin in metastatic pancreatic cancer was terminated, with results posted on 2025-11-17.

• CLINICAL_TRIALS withdrawal · 2025-11-17
  Clinical Trial Update: A Phase II Study to Evaluate GFH375 in Patients With KRAS G12D Mutant Metastatic Pancreatic Cancer [Phase 2]

  A Phase II study evaluating GFH375 in KRAS G12D-mutant metastatic pancreatic cancer has been withdrawn.

• CLINICAL_TRIALS research · 2025-11-17
  Clinical Trial Update: Clinical Study of mRNA Vaccine Combined With PD-1 Inhibitor as Adjuvant Therapy for Postoperative Pancreatic Cancer [EARLY_Phase 1]

  An early-phase clinical trial is evaluating an adjuvant therapy combining an mRNA vaccine with a PD-1 inhibitor for postoperative, resectabl…

• CLINICAL_TRIALS research · 2025-11-17
  Clinical Trial Update: Adebrelimab Infusion Plus Standard Care for Pancreatic Cancer With Pleural or Peritoneal Effusions [Phase 2]

  Phase 2 trial evaluating Adebrelimab in combination with standard care for metastatic pancreatic cancer with pleural or peritoneal effusions…

• CLINICAL_TRIALS trial_result · 2025-11-17
  Clinical Trial Update: Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma [Phase 1, Phase 2]

  Phase 1/2 clinical trial of SOT102 antibody-drug conjugate in advanced gastric and pancreatic adenocarcinoma has been terminated; results ha…

• CLINICAL_TRIALS research · 2025-11-17
  Clinical Trial Update: Clinical Study of 177Lu-CTR-FAPI In the Treatment of Patients With Advanced, Metastatic Solid Tumors [EARLY_Phase 1]

  This entry describes an early-phase (Phase 1) clinical trial evaluating Lutetium-177 labeled CTR-FAPI for pancreatic cancer and other advanc…

• CLINICAL_TRIALS research · 2025-11-17
  Clinical Trial Update: A Clinical Study Evaluating the Safety, Tolerability, Preliminary Efficacy and Immunogenicity of a Tumor Vaccine Injection Targeting Stressinducible Proteins MICA/B in Combination With the AG Regimen in Patients With Metastatic Pancreatic Cancer [EARLY_Phase 1]

  An early-phase 1 clinical study evaluating a MICA/B-targeted tumor vaccine with the AG chemotherapy regimen in metastatic pancreatic cancer;…

• CLINICAL_TRIALS research · 2025-11-14
  Clinical Trial Update: Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC [Phase 3]

  Phase 3 trial assessing intra-arterial gemcitabine versus intravenous gemcitabine with nab-paclitaxel following radiotherapy in locally adva…

• CLINICAL_TRIALS research · 2025-11-13
  Clinical Trial Update: Redefining FOLFIORINOX in Older Pancreatic Cancer Patients [Phase 2]

  This document reports a Phase 2 trial updating the use of the FOLFIRINOX regimen in older patients with metastatic pancreatic cancer. The st…

• CLINICAL_TRIALS research · 2025-11-13
  Clinical Trial Update: Stereotactic Magnetic Resonance Guided Radiation Therapy [NA]

  Clinical trial update on stereotactic MR-guided radiation therapy for multiple cancer types; recruitment is ongoing.

• FDA approval · 2025-11-12
  FDA Tentative Approval: FLUOROURACIL — Supplemental Application (Gland Pharma Limited)

  FDA Tentative Approval for Fluorouracil from Gland Pharma Limited under an ANDA, indicating a pathway to U.S. market subject to regulatory t…

• CLINICAL_TRIALS research · 2025-11-12
  Clinical Trial Update: ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies [Phase 1]

  Phase 1 clinical trial update for ProAgio in previously treated advanced pancreatic cancer and other solid tumor malignancies; the study is …