Pancreatic Cancer
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer [Phase 2]
Phase 2 trial results have been posted for a combination of CRS-207, pembrolizumab, ipilimumab, and tadalafil in metastatic pancreatic cance…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Study of a New Technique for Imaging Pancreatic Cancer [Phase 1]
Phase 1 study evaluating a novel imaging technique for pancreatic cancer has completed, including tumors expressing the CA19-9 biomarker.
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001) [Phase 1]
Phase 1 study of mRNA-5671/V941 as monotherapy and in combination with pembrolizumab (V941-001) was terminated, with results posted on 2025-…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Liposomal Irinotecan, S-1, and Oxaliplatin in Advanced Pancreatic Adenocarcinoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating a triplet regimen of liposomal irinotecan, S-1, and oxaliplatin in advanced pancreatic cancer (pancre…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Study of HuMab-5B1 (MVT-5873) in Subjects With Pancreatic Cancer or Other Cancer Antigen 19-9 (CA19-9) Positive Malignancies [Phase 1]
A Phase 1 study of HuMab-5B1 (MVT-5873) in CA19-9 positive malignancies, including pancreatic cancer, has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: CPI-613 in Combination With Modified FOLFIRINOX in Locally Advanced Pancreatic Cancer [Phase 1, Phase 2]
This update reports completed Phase 1 and Phase 2 arms of a study evaluating CPI-613 in combination with a modified FOLFIRINOX regimen in lo…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian Cancer [Phase 1]
A Phase 1 trial from the University of Michigan evaluates talazoparib in combination with belinostat in metastatic breast cancer, metastatic…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Using Catumaxomab/Catuvab Device [NA]
A completed validation trial evaluated removal of EpCAM-positive tumor cells from blood collected during tumor surgery using the Catumaxomab…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients with Pancreatic Cancer [EARLY_Phase 1]
An early-phase trial evaluated neoadjuvant chemotherapy and radiation therapy followed by gemcitabine in patients with pancreatic cancer, an…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers [Phase 1, Phase 2]
This is an update on Claudin18.2-targeted CAR-T therapy CT041 for gastric and pancreatic cancers (and related digestive cancers), showing ph…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 is Administered in Combination With IV Modified FOLFIRINOX (mFFX) With or Without IV Budigalimab Compared to mFFX in Adult Participants With Untreated Pancreatic Cancer Metastasis [Phase 1]
A Phase 1 trial evaluating safety and changes in disease activity when ABBV-927 is infused with modified FOLFIRINOX, with or without budigal…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer [Phase 1]
Phase 1 trial evaluating disulfiram in combination with chemotherapy for patients with refractory solid tumors or metastatic pancreatic canc…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Metronomic Capecitabine with Camrelizumab and Apatinib Mesylate for Treatment of Advanced Pancreatic Cancer [Phase 2]
Phase 2 clinical trial evaluating metronomic capecitabine with camrelizumab and apatinib mesylate for advanced pancreatic cancer; the study …
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer [Phase 2]
Phase II randomized study of mFOLFIRINOX with or without ramucirumab in advanced pancreatic cancer; results posted in 2025.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study evaluating CM24 in combination with nivolumab in adults with advanced…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab [Phase 1]
Phase 1 trial evaluating dasatinib to prevent oxaliplatin-induced neuropathy in patients with metastatic gastrointestinal cancers receiving …
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors [Phase 1, Phase 2]
An update on the Phase 1/2 study of CYT-0851 in B-cell malignancies and advanced solid tumors, noting completion of Phase 1/2 cohorts.
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC [Phase 2]
A Phase 2 clinical trial update evaluating nanoliposomal irinotecan with XELOX plus cadonilimab (AK104) as first-line treatment for advanced…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Dose Escalation Trial of Stereotactic Body Radiotherapy (SBRT) After Induction Chemotherapy for Locally Advanced Pancreatic Cancer [Phase 1]
A Phase 1 dose-escalation study evaluating stereotactic body radiotherapy following induction chemotherapy for locally advanced pancreatic c…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms [NA]
This entry notes the completion of a clinical trial evaluating a comprehensive electronic cancer support system for managing cancer-related …
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy [Phase 1, Phase 2]
Phase 1/2 study of the NANT pancreatic cancer vaccine by ImmunityBio, in patients who progressed on or after standard therapy, has been term…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Navigating the Learning Curve of Robotic Pancreatoduodenectomy: Feasibility, Proficiency, and Mastery in a First-generation Surgeon
A completed University of Pisa study examines the feasibility, learning curve, and mastery of robotic pancreatoduodenectomy performed by a f…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: NEO-adjuvant Chemo-immunotherapy in Pancreatic Cancer [Phase 2]
This is a Phase 2 trial update for neoadjuvant chemo-immunotherapy in pancreatic cancer. The study is currently active but not recruiting.