Overweight

• CLINICAL_TRIALS trial_result · 2025-12-22
  Clinical Trial Update: A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN) [Phase 3]

  Phase 3 ATTAIN-MAINTAIN evaluated Orforglipron for maintenance of body weight reduction in adults with obesity or overweight and weight-rela…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Open Trial [NA]

  An open, completed clinical trial from The Miriam Hospital investigating whether reducing weight bias internalization can improve weight man…

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: Tirzepatide Combined With Cognitive-Behavioural Therapy (CBT) for Adults With Alcohol Use Disorder (AUD) and Overweight/Obesity (OOB) [Phase 2]

  Phase 2 clinical trial evaluating tirzepatide combined with cognitive-behavioral therapy for adults with alcohol use disorder and overweight…

• CLINICAL_TRIALS withdrawal · 2025-12-18
  Clinical Trial Update: A Phase 3, Double-blind/Double-dummy, Safety/Efficacy/Superiority of Sibutramine/Topiramate XR in Adults With Overweight [Phase 3]

  A Phase 3 trial evaluating sibutramine with extended-release topiramate in adults with overweight/obesity has been withdrawn.

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: CARE Trial: Comparing Different Levels of Calorie Reduction for Weight Loss [NA]

  A completed clinical trial (CARE trial) comparing different levels of daily calorie reduction for weight loss. It is sponsored by the Univer…

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• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Changes in Muscle Strength, Inflammatory Markers, and Body Composition in Response to Alternate Day Fasting Combined With Krill Oil Supplementation in Adults With Overweight and Obesity [NA]

  This completed trial evaluated the effects of alternate day fasting combined with krill oil supplementation on muscle strength, inflammatory…

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: COMPASS 65+ - Community-based Physical Activity Snacks for Healthy Aging in Overweight and Obese Aged Adults [NA]

  Clinical trial update for COMPASS 65+, a community-based physical activity snack program aimed at healthy aging in overweight/obese adults a…

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Phase Ia Clinical Study of HDM1005 Injection [Phase 1]

  This document reports the completion of a Phase Ia clinical study of the HDM1005 Injection for obesity and overweight. No efficacy data is p…

• CLINICAL_TRIALS trial_result · 2025-12-16
  Clinical Trial Update: Phase Ib Clinical Study of HDM1005 Injection [Phase 1]

  This document notes the completion of the Phase 1 portion of a Phase Ib study of the HDM1005 injection for overweight and obesity.

• CLINICAL_TRIALS research · 2025-12-16
  Clinical Trial Update: Redox Status and Exercise Training-induced Adaptations [NA]

  The University of Thessaly is conducting a clinical trial on redox status and exercise training-induced adaptations in adults who are overwe…

• CLINICAL_TRIALS research · 2025-12-15
  Clinical Trial Update: A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or Obesity [Phase 2]

  A Phase 2 clinical trial investigating different doses of the experimental medicine NNC0662-0419 in adults with overweight or obesity. Recru…

• CLINICAL_TRIALS research · 2025-12-15
  Clinical Trial Update: Effect of High-intensity Interval Training on Cardiometabolic Health and Physical Fitness in Young Adults With Obesity [NA]

  Clinical trial update indicates enrollment by invitation for a study on high-intensity interval training and its effects on cardiometabolic …

• CLINICAL_TRIALS trial_result · 2025-12-12
  Clinical Trial Update: A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or Obesity [Phase 1]

  A Phase 1 study comparing blood levels of cagrilintide and semaglutide after combined versus separate injections in adults with overweight o…

• CLINICAL_TRIALS research · 2025-12-12
  Clinical Trial Update: Immediate Effect of Whole-Body Vibration on Cardiovascular Response and Functional Capacity in Overweight/Obese Young Women [NA]

  Clinical trial update indicating ongoing recruitment for a study evaluating the immediate cardiovascular effects and functional capacity of …

• CLINICAL_TRIALS research · 2025-12-12
  Clinical Trial Update: Study on Gastric Emptying Effect and Drug-Drug Interactions of GZR18 Injection [Phase 1]

  Phase 1 clinical trial evaluating gastric emptying effects and potential drug-drug interactions of GZR18 injection in individuals with obesi…

• CLINICAL_TRIALS research · 2025-12-12
  Clinical Trial Update: The Effects of Almond Consumption on Functional Performance and Activity in Overweight Active Older Adults [NA]

  A Florida State University clinical trial examines whether almond consumption impacts functional performance and activity in overweight, act…

• CLINICAL_TRIALS trial_result · 2025-12-10
  Clinical Trial Update: Body Fat Reducing Effect and Safety of Enzymatically Modified Isoquercitrin in Overweight and Obese Subjects [NA]

  A completed clinical trial evaluated the body fat reducing effects and safety of enzymatically modified isoquercitrin (EMIQ) in overweight a…

• CLINICAL_TRIALS trial_result · 2025-12-10
  Clinical Trial Update: Overweight Management and Social Inequalities [NA]

  A completed clinical trial update from INSERM, France, on overweight management and its relationship to social inequalities.

• CLINICAL_TRIALS research · 2025-12-10
  Clinical Trial Update: Behavioral Weight Loss and Sleep Health Intervention [NA]

  A clinical trial update from the University of Colorado, Denver, recruiting overweight and obese adults for a behavioral weight loss and sle…

• CLINICAL_TRIALS trial_result · 2025-12-04
  Clinical Trial Update: Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1) [Phase 3]

  This entry notes the completed Phase 3 OASIS 1 trial evaluating daily oral semaglutide tablets for obesity and overweight.

• CLINICAL_TRIALS research · 2025-12-04
  Clinical Trial Update: Abdominal and Core Exercises on Respiratory Functions in Obese and Overweight Women (COREBREATH) [NA]

  The COREBREATH clinical trial tests whether abdominal and core exercises can improve respiratory function in obese and overweight women and …

• CLINICAL_TRIALS trial_result · 2025-12-03
  Clinical Trial Update: Impact of Whole-Body Vibration on Anthropometric Measurement and Body Composition in Overweight and Obese University Students [NA]

  A completed clinical trial from Cairo University evaluating the impact of whole-body vibration on anthropometric measures and body compositi…

• CLINICAL_TRIALS research · 2025-12-03
  Clinical Trial Update: Impact of Eating Beans on Metabolism [NA]

  This completed clinical trial investigates the effect of bean consumption on metabolism in overweight individuals.

• CLINICAL_TRIALS research · 2025-12-03
  Clinical Trial Update: Train Your Brain - Executive Function [NA]

  This clinical trial update notes that the USDA Grand Forks Human Nutrition Research Center-sponsored study 'Train Your Brain - Executive Fun…

• CLINICAL_TRIALS research · 2025-11-28
  Clinical Trial Update: Plant-Based Foods and (Poly)Phenol Supplementation in Gut Microbiota Modulation, Body Weight, and Cardiometabolic Risk [NA]

  This entry reports on an ongoing clinical trial evaluating whether plant-based foods and polyphenol supplementation modulate gut microbiota,…