Ovarian Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-08-02Clinical Trial Update: Platine, Avastin and OLAparib in 1st Line [Phase 3]
Phase 3 trial update involving Platine, Avastin, and OLAparib in first-line ovarian cancer has completed.
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FDA approval · 2022-07-27FDA Approved: PACLITAXEL PROTEIN BOUND PARTICLES ALBUMIN BOUND — Original Application (American Regent, Inc.)
FDA approved paclitaxel protein-bound particles albumin-bound (paclitaxel) from American Regent, Inc. under an Original Application (NDA2118…
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Adjuvant Chemotherapy of Three-step Regimen in Ovarian Cancer [Phase 2]
Phase 2 clinical trial update evaluating a three-step adjuvant chemotherapy regimen in ovarian cancer.
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Adjuvant Chemotherapy of Three-step Regimen in BRCA1/2 Wide Type Ovarian Cancer (ACTS-2) [Phase 3]
A Phase 3 clinical trial update on an adjuvant three-step chemotherapy regimen for BRCA1/2 wild-type ovarian cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: Pembrolizumab and Carboplatin in Treating Patients With Relapsed or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pembrolizumab in combination with carboplatin for relapsed or refractory ovarian, fallopian tube, or p…
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EMA guidance · 2022-07-22EMA recommends restricting use of cancer medicine Rubraca
EMA recommends restricting the use of the cancer medicine Rubraca (rucaparib) to specific patient groups due to safety or effectiveness cons…
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: Evaluation of Optimal Treatment Duration of Bevacizumab Combination With Standard Chemotherapy in Patients With Ovarian Cancer [Phase 3]
Phase 3 clinical trial evaluating the optimal duration of bevacizumab in combination with standard chemotherapy for ovarian cancer has compl…
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CLINICAL_TRIALS trial_result · 2022-07-08Clinical Trial Update: Intraperitoneal Aerosol High-pressure Chemotherapy for Women With Recurrent Ovarian Cancer [Phase 2]
Phase 2 trial update of intraperitoneal aerosol high-pressure chemotherapy for recurrent ovarian cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-06-21Clinical Trial Update: Phase 2 Study of OTL38 for Intra-operative Imaging of Folate Receptor-alpha Positive Ovarian Cancer [Phase 2]
Phase 2 study of OTL38 for intra-operative imaging in folate receptor-alpha positive ovarian cancer has completed with posted results in 202…
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CLINICAL_TRIALS trial_result · 2022-06-21Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab [Phase 1, Phase 2]
A Phase 1/2 trial evaluating a vaccine therapy in combination with trastuzumab for patients with Stage IV HER2-positive breast cancer or ova…
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CLINICAL_TRIALS trial_result · 2022-06-16Clinical Trial Update: Envafolimab, Lenvatinib Combined With VP-16 in Platinum-resistant Recurrent Epithelial Ovarian Cancer [Phase 2]
Phase 2 trial exploring Envafolimab and Lenvatinib combined with VP-16 for platinum-resistant recurrent epithelial ovarian cancer is underwa…
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CLINICAL_TRIALS trial_result · 2022-06-10Clinical Trial Update: First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer [Phase 2]
A Phase 2 trial evaluating first-line bevacizumab, carboplatin, and paclitaxel in stage III-IV ovarian, primary peritoneal, and fallopian tu…
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CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1 [Phase 1, Phase 2]
Phase 1/2 trial evaluating NY-ESO-1–targeted T-cell therapy with or without decitabine in patients with NY-ESO-1–expressing advanced cancers…
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CLINICAL_TRIALS trial_result · 2022-05-17Clinical Trial Update: Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors [Phase 2]
Phase 2 trial evaluating autologous peripheral blood stem cell transplant for germ cell tumors (childhood germ cell tumor and ovarian cancer…
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CLINICAL_TRIALS trial_result · 2022-05-12Clinical Trial Update: Efficacy of Primary Debulking Surgery Versus Neoadjuvant Chemotherapy in Stage IV Ovarian Cancer [Phase 3]
Phase 3 trial comparing primary debulking surgery to neoadjuvant chemotherapy for stage IV ovarian cancer.
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CLINICAL_TRIALS trial_result · 2022-04-27Clinical Trial Update: Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 trial investigating dasatinib combined with ifosfamide, carboplatin, and etoposide in young patients with metastatic or recu…
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: Pembrolizumab and Bevacizumab With Chemotherapy Followed by Pembrolizumab, Bevacizumab and Olaparib in Recurrent Ovarian Cancer [Phase 2]
Phase 2 trial evaluating pembrolizumab and bevacizumab with chemotherapy followed by pembrolizumab, bevacizumab, and olaparib in recurrent o…
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: A Study of Fluzoparib±Apatinib Versus Placebo Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on First-Line Platinum-Based Chemotherapy [Phase 3]
Phase 3 trial evaluating Fluzoparib with or without Apatinib versus placebo for maintenance in advanced ovarian cancer after response to fir…
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CLINICAL_TRIALS trial_result · 2022-04-22Clinical Trial Update: Clinical Study on the Safety, Pharmacokinetics, and Efficacy of ScTIL (Genetically Modified Tumor Infiltrating Lymphocytes) in the Treatment of Gynecological Malignancies [Phase 2]
Phase 2 clinical trial evaluating ScTILs (genetically modified tumor infiltrating lymphocytes) for cervical and ovarian cancers (and maligna…
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CLINICAL_TRIALS withdrawal · 2022-04-15Clinical Trial Update: Secondary Cytoreductive Surgery in Platinum-resistant Recurrent Ovarian Cancers [Phase 2, Phase 3]
Clinical trial evaluating secondary cytoreductive surgery in platinum-resistant recurrent ovarian cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: Intraperitoneal Paclitaxel and Carboplatin in the Treatment of Women With Carcinoma of Mullerian Origin [Phase 2]
Phase 2 trial update evaluating intraperitoneal paclitaxel and carboplatin in women with carcinoma of Mullerian origin starting with ovarian…
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FDA approval · 2022-04-13FDA Approved: ALYMSYS — Original Application (Amneal Pharmaceuticals LLC)
FDA approves ALYMSYS as a biosimilar to bevacizumab (bevaczizumab-maly) from Amneal Pharmaceuticals LLC under an original Biologics License …
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CLINICAL_TRIALS trial_result · 2022-04-13Clinical Trial Update: Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status [Phase 2]
Phase 2 trial update on olaparib tablets for ovarian cancer with varying homologous recombination deficiency (HRD) status shows completed re…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers [Phase 1, Phase 2]
A Phase 1/2 trial update reports completed results for combining topotecan with the ATR inhibitor berzosertib (VX-970/M6620) in small cell c…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Effect of Albumin-bound Paclitaxel Plus Carboplatin Compared With Paclitaxel Plus Carboplatin in Patients Receiving Neoadjuvant Chemotherapy for Advanced Ovarian, Fallopian Tube or Peritoneal Cancer: A Phase 2 Single Center Clinical Trial [Phase 2]
Phase 2 trial comparing albumin-bound paclitaxel plus carboplatin vs paclitaxel plus carboplatin in neoadjuvant setting for advanced ovarian…