Osteoarthritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients [Phase 2, Phase 3]
A clinical trial update noting the completion of Phase 2 and Phase 3 studies evaluating methylprednisolone for orthostatic intolerance and h…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: ROBODOC® Clinical Trials: Long-Term Follow-Up
This document reports long-term follow-up results from ROBODOC clinical trials in patients with osteoarthritis.
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Prospective Study Measuring Clinical Outcomes of Knee Arthroplasty Using the VERASENSE™ Knee System
A completed prospective study evaluated clinical outcomes of knee arthroplasty using the VERASENSE Knee System.
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: Treatment Outcomes for Ankle Arthritis
Completed clinical trial update reporting treatment outcomes for ankle arthritis in osteoarthritis. Results were posted on 2016-12-21.
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CLINICAL_TRIALS withdrawal · 2016-12-15Clinical Trial Update: Radiostereometric Analysis (RSA) of the PROFEMUR® Preserve Classic Femoral Components [NA]
A clinical trial evaluating Radiostereometric Analysis of PROFEMUR Preserve Classic Femoral Components has been withdrawn.
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CLINICAL_TRIALS research · 2016-12-14Clinical Trial Update: Ultra-Congruent(UC) Versus Posterior-stabilized(PS) Insert in Bilateral Total Knee Arthroplasty [NA]
A clinical trial update comparing Ultra-Congruent inserts to Posterior-stabilized inserts in bilateral total knee arthroplasty; current stat…
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CLINICAL_TRIALS research · 2016-12-14Clinical Trial Update: Conventional Versus Patient-specific Instruments in Total Knee Arthroplasty [NA]
A clinical trial is evaluating conventional versus patient-specific instruments in total knee arthroplasty for osteoarthritis, with the stat…
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CLINICAL_TRIALS withdrawal · 2016-12-01Clinical Trial Update: The Effect of Intra-articular Pulsed Radiofrequency in Osteoarthritis [NA]
A clinical trial assessing intra-articular pulsed radiofrequency for osteoarthritis has been withdrawn; no results are reported.
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis [NA]
Completed clinical trial evaluating the impact of intraarticular corticosteroids on bone turnover in osteoarthritis; results are posted.
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FDA approval · 2016-11-25FDA Approved: DICLOFENAC SODIUM AND MISOPROSTOL — Original Application (Amneal Pharmaceuticals LLC)
The FDA approved Amneal Pharmaceuticals LLC's diclofenac sodium and misoprostol as an original ANDA, enabling a generic version of the diclo…
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CLINICAL_TRIALS research · 2016-11-17Clinical Trial Update: Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty [Phase 4]
Clinical trial update for a Phase 4 study evaluating intrathecal and intravenous Dexmetomidine in addition to spinal anesthesia for total kn…
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CLINICAL_TRIALS trial_result · 2016-11-16Clinical Trial Update: Chronic Muscle Disuse in the Elderly [NA]
The University of Vermont reports the completion of a clinical trial investigating chronic muscle disuse in the elderly with Osteoarthritis.
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CLINICAL_TRIALS other · 2016-11-16Clinical Trial Update: Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty [NA]
A clinical trial comparing regional anesthetic blocks to periarticular infiltration for postoperative pain after direct anterior total hip a…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.
This clinical trial update reports mid-term outcomes for the first metatarsophalangeal joint arthroplasty using the Primus FGT implant in pa…
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Intraoperative Sedatives and Postoperative Pain [Phase 4]
This trial update reports the completion of a Phase 4 study evaluating the effect of intraoperative sedatives on postoperative pain in patie…
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CLINICAL_TRIALS withdrawal · 2016-10-26Clinical Trial Update: OASIS: Osteoarthritis Sensitivity Integration Study [NA]
The OASIS trial evaluating osteoarthritis sensitivity integration has been withdrawn from the registry. No further development or results ar…
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CLINICAL_TRIALS research · 2016-10-21Clinical Trial Update: Role of ASICs in Human Inflammatory Pain
The update covers research on the role of acid-sensing ion channels (ASICs) in human inflammatory pain. It lists several inflammatory diseas…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP) [Phase 3]
Open-label Phase 3 safety and tolerability study of COV155 in adults with osteoarthritis (knee or hip) and chronic low back pain has complet…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: The Clinical Safety of Alcoholic Extract Sahastara Remedy of Extract Capsule in Healthy Volunteers [Phase 1]
Phase 1 safety study of an alcoholic extract Sahastara remedy capsule in healthy volunteers has completed, evaluating safety endpoints in th…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: A Randomised Multi-centre Study to Compare the Long-term Performance of the Future Hip to 3 Other Implants in Primary Total Hip Replacement [Phase 3]
A Phase 3 randomized multi-centre study comparing the Future Hip implant with three other implants in primary total hip replacement has been…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement [Phase 4]
Phase 4 clinical trial update evaluating the long-term performance of the Pinnacle Cup with a ceramic-on-ceramic bearing in primary total hi…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement [Phase 4]
A Phase 4 clinical trial evaluated the long-term performance of the Pinnacle hip cup with a metal-on-metal bearing in primary total hip repl…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: MRI of Infrapatellar Fat Pad in Osteoarthritis
Completed results posted for an imaging study assessing the infrapatellar fat pad in osteoarthritis.
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CLINICAL_TRIALS trial_result · 2016-10-05Clinical Trial Update: fMRI Evaluation of Pain Central Sensitization Phenomena in Subjects With Knee Osteoarthritis
A completed clinical trial evaluating fMRI biomarkers of pain central sensitization phenomena in people with knee osteoarthritis. Sponsor: P…
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CLINICAL_TRIALS research · 2016-10-05Clinical Trial Update: The Investigation of the Depression in Osteoarthritis
Clinical trial update from Dalian Municipal Central Hospital studying depression in individuals with osteoarthritis. The current status of t…