Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: A Comparison of 2-octyl Cyanoacrylate Skin Adhesive and Polyester Mesh for Wound Closure in Total Knee Arthroplasty, A Randomized Controlled Study [NA]
This randomized controlled trial compared 2-octyl cyanoacrylate skin adhesive with polyester mesh for wound closure in total knee arthroplas…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Investigation of the Effect of Movement Mobilization Concept on Sensory, Pain, Muscle Activation in Patients With Knee Osteoarthritis [NA]
A completed clinical trial assessing the effect of a movement mobilization concept on sensory outcomes, pain, and muscle activation in knee …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty [Phase 4]
This is a Phase 4 clinical trial evaluating nerve blocks plus local infiltration analgesia for pain control in knee arthroplasty due to oste…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Molecular Mechanisms Underlying Hip and Knee Osteoarthritis in Patients Undergoing Primary Elective Arthroplasty
A clinical trial update from the Medical University of Warsaw describes a study investigating molecular mechanisms underlying hip and knee o…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty [NA]
A completed clinical trial update from Queen Savang Vadhana Memorial Hospital evaluating patellar denervation during total knee arthroplasty…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Development and Measurement of the Effects of a Digital Education Solution for Patients Undergoing Total Hip or Knee Arthroplasty [NA]
A clinical trial is being developed to measure the effects of a digital education solution for patients undergoing total hip or knee arthrop…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques [NA]
This clinical trial update describes a randomized comparison of sciatic, BiFeS, and IPACK nerve block techniques added to an adductor canal …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Impact of ABC-X Model Nursing on Psychological Resilience and Family Function in TKA Patients
This clinical trial evaluates the ABC-X Model Nursing approach's effect on psychological resilience and family function in patients undergoi…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty [NA]
A clinical trial update describes a study comparing different corticosteroid doses in local infiltration analgesia for total knee arthroplas…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty [Phase 4]
This clinical trial update explores patient outcomes comparing general anesthesia versus spinal anesthesia in outpatient primary total knee …
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CLINICAL_TRIALS other · 2026-01-12Clinical Trial Update: The Effects of Healthy Lifestyle Management Training and Personalized Physical Activity Counseling: A Randomized Controlled Trial [NA]
This clinical trial investigates whether healthy lifestyle management training plus personalized physical activity counseling can improve ou…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Effects of Tourniquet Applied During Total Knee Replacement Surgery on Patient Hemodynamics and Blood Table
Clinical trial update on the effects of using a tourniquet during total knee replacement on patient hemodynamics and blood parameters (compl…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplasty [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating analgesic efficacy of a pre-operative dose of Palmitoylethanolamide in patients undergoing total kn…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Impact of Breathing and Yoga Poses on Kinesiophobia in Knee Osteoarthritis Patients [NA]
A completed clinical trial from Saveetha University examined whether breathing techniques and yoga poses can reduce kinesiophobia in patient…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Long-Term Effects of Mobithron Advance on Knee Osteoarthritis Aims to Investigate the Effects of Mobithron Advance on OA Progression [EARLY_Phase 1]
This clinical trial update describes an early-phase 1 study by Universiti Sains Malaysia to evaluate the long-term effects of Mobithron Adva…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Neurolysis for the Treatment of Medial Chronic Knee Pain Due to Osteoarthritis [NA]
A clinical trial is currently recruiting to evaluate neurolysis for medial chronic knee pain due to osteoarthritis. The sponsor is FUSMobile…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Ultrasound-Guided PASC Block vs Femoral-Sciatic Nerve Block for Postoperative Analgesia After Total Knee Arthroplasty [NA]
Completed clinical trial comparing ultrasound-guided PASC block with femoral-sciatic nerve block for postoperative analgesia after total kne…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Novel Transdermal Ketoprofen Gel Formulation for Knee Osteoarthritis [Phase 1]
Phase 1 clinical trial update for a novel transdermal ketoprofen gel intended to treat knee osteoarthritis; the study is currently active bu…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement [NA]
This clinical trial from Hong Kong compares nurse-led telehealth follow-up with in-person follow-up after total knee replacement and is curr…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis [Phase 1, Phase 2]
Clinical trial update for intra-articular CX-011 to treat knee osteoarthritis; a Phase 1/Phase 2 study currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: The Effects of Functional Electrical Stimulation (FES) and Exercise on the Quadriceps in Patients With Knee Osteoarthritis
A clinical trial evaluating the effects of functional electrical stimulation and exercise on the quadriceps in knee osteoarthritis is curren…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee [Phase 3]
Phase 3 trial evaluating TG-C for knee osteoarthritis (Kellgren-Lawrence grade 2-3); trial is currently active but not recruiting, sponsored…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia [Phase 4]
A Phase 4 clinical trial completed by Seoul National University Hospital evaluating the ideal sedation dosage for obese patients undergoing …
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Evaluation of CYT-108, A Recombinant Protease Inhibitor, for Treatment of Mild To Moderate Primary Osteoarthritis Of The Knee [Phase 1]
This document reports the completion of a Phase 1 clinical trial evaluating CYT-108, a recombinant protease inhibitor, for mild-to-moderate …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Prepare II - Predictive Model Training and External Validation
This clinical trial update notes that the Prepare II study on hip and knee osteoarthritis is currently recruiting, focusing on training and …