Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2015-02-09Clinical Trial Update: Is Phonophoresis Treatment Effective? [NA]
Clinical trial update from Cukurova University assessing the effectiveness of phonophoresis for knee osteoarthritis; the current status is u…
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Total Knee Arthroplasty Analgesia: Single-shot Femoral Nerve Block or Epidural? [NA]
A completed clinical trial comparing single-shot femoral nerve block versus epidural analgesia for postoperative pain management after total…
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CLINICAL_TRIALS research · 2015-01-21Clinical Trial Update: Development of Knee Osteoarthritis After Arthroscopic Partial Resection of Degenerative Meniscus Tear [Phase 4]
This entry reports an ongoing Phase 4 clinical trial studying whether knee osteoarthritis develops after arthroscopic partial resection of a…
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CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1/2 results for autologous mesenchymal stem cell therapy in osteoarthritis of the knee.
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CLINICAL_TRIALS trial_result · 2015-01-14Clinical Trial Update: Topical Versus Intravenous Tranexamic Acid in Total Knee Arthroplasty [Phase 2]
A completed Phase 2 study evaluated topical versus intravenous tranexamic acid in total knee arthroplasty.
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CLINICAL_TRIALS trial_result · 2015-01-01Clinical Trial Update: Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee [NA]
Completed clinical trial evaluating a home-based exercise and weight-control program to manage pain in overweight elderly individuals with k…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Effect of Adductor Canal Block vs. Placebo on Muscle Strength, Mobilisation and Pain After Total Knee Arthroplasty [Phase 4]
A Phase 4 randomized trial compared adductor canal block with placebo after total knee arthroplasty to evaluate effects on muscle strength, …
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty [NA]
A completed clinical trial comparing a single-shot sciatic nerve block to posterior capsule/fat pad infiltration of local anesthetic for pai…
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Management of Postoperative Pain After Total Knee Replacement. [Phase 4]
This is a Phase 4 clinical trial update on managing postoperative pain after total knee replacement. The trial has completed and results wer…
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CLINICAL_TRIALS research · 2014-11-03Clinical Trial Update: Trial to Assess the Structural Effect and Long-term Symptomatic Relief of Intra-articular Injections of Hyaluronic Acid in Primary Knee OA [NA]
A clinical trial update describing a study that assesses the structural effect and long-term symptomatic relief of intra-articular hyaluroni…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Use of Autologous Adipose-Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee [Phase 1]
A Phase 1 clinical trial evaluating autologous adipose-derived stromal vascular fraction for knee osteoarthritis has completed, according to…
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CLINICAL_TRIALS research · 2014-10-27Clinical Trial Update: Outcome Comparison of Two Total Knee Arthroplasty Systems: e.Motion-Pro Versus Genesis II [NA]
A clinical trial update evaluating two total knee arthroplasty systems, e.Motion-Pro and Genesis II, for knee osteoarthritis. The sponsor is…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy [Phase 4]
Phase 4 trial comparing allograft bone graft to a synthetic bone substitute in high tibial osteotomy for knee osteoarthritis; the update pre…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee [Phase 2]
Phase 2 efficacy trial of OLT1177 Gel for knee osteoarthritis has completed; the document summarizes the trial status rather than presenting…
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CLINICAL_TRIALS withdrawal · 2014-09-17Clinical Trial Update: Biochemical Approach to Measuring Surgical Trauma
The clinical trial NCT01037400 evaluating a biochemical approach to measuring surgical trauma in total knee replacement has been withdrawn.
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CLINICAL_TRIALS research · 2014-09-09Clinical Trial Update: Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR) [Phase 4]
This document provides a Phase 4 trial update comparing femoral nerve catheter versus adductor canal block with a steroid adjuvant for analg…
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Comparison of Surgical Time and Efficiency of Total Knee Arthroplasty [NA]
A completed clinical trial comparing surgical time and efficiency of total knee arthroplasty sponsored by DePuy Orthopaedics.
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Safety, Tolerability, and Efficacy of IA Verapamil in the Treatment of Joint Pain in Subjects With Osteoarthritis of the Knee [Phase 1, Phase 2]
Phase 1/2 trial evaluating intra-articular verapamil for knee osteoarthritis was terminated; results were posted in 2014.
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CLINICAL_TRIALS other · 2014-08-19Clinical Trial Update: Ketamine Prevent POCD [NA]
Clinical trial update about using ketamine to prevent postoperative cognitive dysfunction; listed conditions are avascular necrosis of the f…
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CLINICAL_TRIALS trial_result · 2014-08-04Clinical Trial Update: Functional Performance of the Journey Deuce Bicompartmental Versus the Genesis II Total Knee System [Phase 4]
Phase 4 trial comparing the Journey Deuce bicompartmental knee implant to the Genesis II total knee system in knee arthroplasty; results hav…
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: How Total Knee Prosthesis Dessigns Influence in Quality of Live
A completed clinical trial evaluating how different total knee prosthesis designs influence quality of life in patients with knee osteoarthr…
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CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: Effects of Kneehab 12-week Peri-operative Total Knee Arthroplasty [Phase 3]
A Phase 3 trial evaluating Kneehab as part of perioperative management for total knee arthroplasty in knee osteoarthritis. The study has com…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
This completed clinical trial from ArthroLab Inc. evaluated MRI-detected structural changes and neuropathic pain in osteoarthritis of the kn…
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Trial to See if Topical Pennsaid for Knee Pain Affects Coagulation Values in Patients Who Are Also Taking Anticoagulants [Phase 3]
A Phase 3 trial evaluated whether topical diclofenac (Pennsaid) affects coagulation values in knee osteoarthritis patients who are also taki…
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CLINICAL_TRIALS trial_result · 2014-06-05Clinical Trial Update: Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee [Phase 2]
The document reports the completion of a Phase 2 crossover trial evaluating the efficacy and safety of SierraSil Joint Formula 14 in knee os…