Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Astaxanthin for Management of Inflammation in Knee Osteoarthritis [Phase 2, Phase 3]
A Phase 2/3 trial evaluating astaxanthin for inflammation in knee osteoarthritis was terminated, with results posted in 2025.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: The Effect of the Physiotherapy Program Added to the ERAS Protocol in Patients With Total Knee Arthroplasty [NA]
A clinical trial evaluating whether adding a physiotherapy program to the ERAS protocol improves outcomes for patients with knee osteoarthri…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Telehealth Exercise and Mindfulness for Pain in Osteoarthritis - Stage 1B [NA]
A Stage 1B clinical trial evaluating telehealth-delivered exercise and mindfulness for knee osteoarthritis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee [Phase 1]
Phase 1 study evaluating safety, tolerability and pharmacokinetics of a single intraarticular dose of 4P004 in patients with knee osteoarthr…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Tourniquet on Total Knee Arthroplasty [NA]
Completed clinical trial evaluating tourniquet use during total knee arthroplasty for knee osteoarthritis; results were posted on 2025-05-15…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study [Phase 2]
Phase 2 randomized trial at Yale comparing a steroid-enhanced nerve block to Exparel (bupivacaine liposome) nerve block for postoperative an…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Proprioceptive Fatigue Adaptation in Osteoarthritis [NA]
A clinical trial investigating proprioceptive fatigue adaptation in knee osteoarthritis is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: A Physical Therapist Administered Physical Activity Intervention After Total Knee Replacement [NA]
A completed clinical trial studied a physical therapist–delivered physical activity program after total knee replacement. Results have been …
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: PT-led Triage for Patients With Hip o Knee Osteoarthritis [NA]
The document reports that a physical therapy–led triage trial for patients with osteoarthritis of the knee and hip is currently active but n…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Examining the Effect of Neuromuscular Exercises on Movement Control in Hip & Knee Osteoarthritis: A Randomised Proof of Concept and Feasibility Study [NA]
A randomized proof-of-concept feasibility trial evaluates whether neuromuscular exercises improve movement control in individuals with hip a…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Impact of Blood-Flow-Restriction Prehabilitation on Pre- and Postoperative Rehabilitation After Total Knee Arthroplasty [NA]
A completed clinical trial from University Hospital Bonn evaluating blood-flow-restriction prehabilitation for improving pre- and postoperat…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis [NA]
This clinical trial update compares Kinesio Taping versus Interferential Current Therapy for knee osteoarthritis; the study is not yet recru…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Can the Use of Virtual Reality Improve TKA Outcomes [NA]
A clinical trial sponsored by the Belfast Health and Social Care Trust is evaluating whether virtual reality can improve outcomes after tota…
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA [Phase 4]
A Phase 4 trial comparing spinal anesthesia to general anesthesia for total hip arthroplasty, total knee arthroplasty, and unicompartmental …
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Robotic Assisted TKA [NA]
A clinical trial evaluating robotic-assisted total knee arthroplasty has completed. The study was sponsored by Rothman Institute Orthopaedic…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Prediction AlgoriThm for regeneraTive Medicine Approach in knEe OA: New Decision-making Process Based on Patient pRofiliNg (PATTERN) [NA]
This clinical trial update describes the PATTERN predictive algorithm for regenerative medicine in knee osteoarthritis and outlines a new pa…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: A Study Evaluating the Safety, Tolerability, and Range of Biologically Active Doses of ICM-203 in Mild to Moderate Knee Osteoarthritis [Phase 1, Phase 2]
A phase 1/2 trial evaluating safety, tolerability, and dose range of ICM-203 in mild to moderate knee osteoarthritis. The study is currently…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Dronabinol After Arthroscopic Surgery [Phase 3]
A Phase 3 clinical trial evaluating dronabinol after arthroscopic knee surgery is currently recruiting, targeting knee osteoarthritis and re…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003 [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of fulranumab monotherapy for osteoarthritis of the hip or knee has completed.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Ecoguided Genicular Nerve Block [NA]
This update reports the completion of a clinical trial evaluating ecoguided genicular nerve block for knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Randomised Total Knee Arthroplasty With Attune S+ or NexGen CR [NA]
This update reports a randomized comparison of Attune S+ and NexGen CR total knee arthroplasty implants. The trial is sponsored by Göteborg …
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Intra-Operative Adductor Canal Blocks [NA]
A clinical trial sponsored by Ottawa Hospital Research Institute is evaluating intra-operative adductor canal blocks for knee osteoarthritis…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Impact of Blood Flow Restriction and Electrical Stimulation on Postoperative Muscle Atrophy and Pain After Total Knee Arthroplasty [NA]
This clinical trial update reports on the effects of blood flow restriction and electrical stimulation on postoperative muscle atrophy and p…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Clinical-randomized Study of the Influence of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Total Knee Arthroplasty [NA]
This ClinicalTrials.gov update reports a completed randomized study evaluating rehabilitation therapy combining strength training and blood …
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Revised Targets for Knee Radiofrequency Ablation
The trial notes revised targets for knee radiofrequency ablation in osteoarthritis knee pain. The study is currently recruiting.