Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Effect of Mulligans Mobilization With Movement in Osteoarthritis Knee. [NA]
A clinical trial evaluating Mulligans Mobilization With Movement for knee osteoarthritis has completed.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Comparison of an Old Versus a New Total Knee Replacement [NA]
This entry provides an update on a clinical trial comparing an old total knee replacement design with a new design for knee osteoarthritis; …
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: CBD for Knee Osteoarthritis [Phase 1, Phase 2]
A clinical trial is evaluating cannabidiol (CBD) for knee osteoarthritis in Phase 1/2. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis: [NA]
A clinical trial evaluating the effect of Vitamin K on lower-extremity function in adults with knee osteoarthritis is ongoing, currently lis…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Tranexamic Acid and Drain Use in Knee Arthroplasty [NA]
Completed clinical trial evaluating tranexamic acid use and drain strategies in knee arthroplasty for osteoarthritis of the knee.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Comparison of Postoperative Pain in Primary Cemented Total Knee Arthroplasty With or Without Drain [NA]
This completed clinical trial compared postoperative pain after primary cemented total knee arthroplasty with drainage versus without draina…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Mesenchymal Stem Cells Derived Exosomes in Osteoarthritis Patients [NA]
This entry notes a clinical trial evaluating mesenchymal stem cell-derived exosomes for knee osteoarthritis, and it is currently recruiting.
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CLINICAL_TRIALS safety_alert · 2025-09-12Clinical Trial Update: Incidence of Adductor Canal Catheter Dislodgment
A clinical trial update reports on the incidence of adductor canal catheter dislodgment in patients undergoing total knee arthroplasty, spon…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Role of Methotrexate in Ultrasound Proven Synovitis in Primary Knee OA [Phase 2]
This is a Phase 2 clinical trial investigating the use of methotrexate for ultrasound-confirmed synovitis in primary knee osteoarthritis, wi…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: A Study to Investigate the Effectiveness, Safety, and Tolerability of MAG200 Solution for Intra-articular Injection Compared With Placebo in Participants Aged 35 to 75 Years of Age With Symptomatic Osteoarthritis of the Knee. [Phase 3]
Phase 3 clinical trial evaluating the safety and efficacy of MAG200 as an intra-articular injection for knee osteoarthritis, comparing MAG20…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Knee Pain Relief After Endovenous Treatment for Lower Limb Varicose Veins: A Prospective Observational Study
A prospective observational study evaluating knee pain relief after endovenous treatment for varicose veins of the lower limb; recruitment h…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Navio Robotic Versus Conventional Total Knee Arthroplasty [NA]
Clinical trial update for Navio robotic-assisted versus conventional total knee arthroplasty, sponsored by Columbia University. The study is…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Knee Osteoarthritis Disabling Pain Program for the Brazilian Unified Health System [NA]
Clinical trial assessing a knee osteoarthritis disabling pain program for the Brazilian Unified Health System has completed.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee [Phase 3]
Phase 3 trial evaluating HP-5000 for osteoarthritis pain of the knee has completed and results have been posted.
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CLINICAL_TRIALS other · 2025-09-04Clinical Trial Update: Evaluation of Triathlon - A New Total Knee Prosthesis System - RSA Triathlon Cruciate Retaining - Cemented vs. Uncemented [NA]
Clinical trial update evaluating the Triathlon RSA cruciate-retaining total knee prosthesis, comparing cemented versus uncemented implants; …
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CLINICAL_TRIALS other · 2025-09-03Clinical Trial Update: Optimization of Obesity for Total Knee Replacement With Glucagon-like Peptide-1 Receptor Agonist [EARLY_Phase 1]
An early-phase 1 clinical trial by The University of Hong Kong evaluating a GLP-1 receptor agonist to optimize obesity in patients undergoin…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee [Phase 2]
Phase 2 clinical trial update investigating how cannabinoids interact with central and peripheral pain pathways in knee osteoarthritis, curr…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Comparison of Distal IPACK and Popliteal Plexus Block Combined With Femoral Triangle Block After Total Knee Arthroplasty [NA]
A clinical trial evaluating distal IPACK and popliteal plexus block combined with a femoral triangle block for pain management after total k…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Generate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects [Phase 2]
Phase 2 trial update exploring a pharmacodynamic model of oxytocin for peripheral analgesia, conducted in knee osteoarthritis; the study was…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction [NA]
A clinical trial update describes an ongoing study evaluating the effect of regional anesthesia on postoperative knee motion and patient sat…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Osteoarthritis Care Tools for Primary Care Providers [NA]
This clinical trial update indicates that enrollment for a study on osteoarthritis care tools for primary care providers is ongoing by invit…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: A First-in-Human Study of XSTEM-OA in Patients With Knee Osteoarthritis [Phase 1, Phase 2]
A first-in-human study of XSTEM-OA for knee osteoarthritis in Phase 1/2 has completed.
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty [NA]
This clinical trial update describes a study evaluating blood flow restriction combined with electrostimulation after knee arthroplasty. The…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Dinalbuphine Sebacate in Postoperative Pain Control After TKA [Phase 4]
Phase 4 trial update of Dinalbuphine Sebacate for postoperative pain control after total knee arthroplasty in knee osteoarthritis; the study…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury
A clinical study is developing computational models to predict cartilage degeneration and pain at multiple time horizons in patients with ea…