Osteoarthritis of the Knee
📧 Sign up to get email alerts when something new happens for Osteoarthritis of the Knee.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS withdrawal · 2025-11-17Clinical Trial Update: Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Replacements Versus Conventional Unicompartmental Knee for Subjects With Primary Arthritis of the Knee Joint Involving One (UKA) Compartment (Medial or Lateral) [NA]
A clinical trial comparing robotic-assisted unicompartmental knee replacement to conventional unicompartmental knee replacement for primary …
-
CLINICAL_TRIALS withdrawal · 2025-09-29Clinical Trial Update: Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.
An expanded access IND using autologous HB-adMSCS is described for bilateral knee pain due to knee osteoarthritis. The status indicates the …
-
CLINICAL_TRIALS withdrawal · 2025-09-25Clinical Trial Update: Efficacy and Safety Study of PG201 Tablet in Patients With Osteoarthritis [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of PG201 Tablet in osteoarthritis of the knee has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2025-08-12Clinical Trial Update: A Study of Oxytocin PK After IV Administration in Healthy Subjects and Advanced Knee Arthritis Subjects [Phase 2]
A Phase 2 study evaluating oxytocin pharmacokinetics after IV administration in healthy subjects and knee osteoarthritis patients has been w…
-
CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating metformin as an adjunct to conventional therapy for knee osteoarthritis has been withdrawn.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS withdrawal · 2025-06-24Clinical Trial Update: Robotic Assisted Knee Arthroplasty - Retain the Anterior Cruciate Ligament or Not [NA]
A clinical trial evaluating robotic-assisted knee arthroplasty with anterior cruciate ligament retention has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2025-02-24Clinical Trial Update: Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain [NA]
A clinical trial evaluating genicular artery embolization for knee osteoarthritis-related pain has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2025-02-03Clinical Trial Update: Group Education & Lifestyle Modification's Impact on Weight Loss & Quality Life of Patients with OA [NA]
A clinical trial evaluating group education and lifestyle modification for weight loss and quality of life in people with obesity and osteoa…
-
CLINICAL_TRIALS withdrawal · 2024-10-09Clinical Trial Update: Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis [Phase 1, Phase 2]
A Phase 1/2 clinical trial update on platelet-rich plasma injections and the effects of NSAIDs on pain and function in knee osteoarthritis, …
-
CLINICAL_TRIALS withdrawal · 2021-11-09Clinical Trial Update: Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed [Phase 3]
Phase 3 trial of resiniferatoxin for knee osteoarthritis was withdrawn. No efficacy results reported in this document.
-
CLINICAL_TRIALS withdrawal · 2021-11-09Clinical Trial Update: A Phase 3 Study to Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee [Phase 3]
Phase 3 study evaluating resiniferatoxin for knee osteoarthritis was withdrawn.
-
CLINICAL_TRIALS withdrawal · 2020-05-06Clinical Trial Update: BMAC in Severe Hip or Knee Osteoarthritis Awaiting Arthroplasty [Phase 2, Phase 3]
A clinical trial of bone-marrow-derived autologous cell therapy (BMAC) in severe hip or knee osteoarthritis awaiting arthroplasty was withdr…
-
CLINICAL_TRIALS withdrawal · 2019-01-23Clinical Trial Update: Physiotherapy and Therapeutic Education After Total Knee Arthroplasty. [NA]
A clinical trial evaluating physiotherapy and therapeutic education after total knee arthroplasty was withdrawn from the registry.
-
CLINICAL_TRIALS withdrawal · 2018-04-25Clinical Trial Update: Kinematics After Total Knee Arthroplasty [NA]
A clinical trial evaluating knee kinematics after total knee arthroplasty has been withdrawn from the registry.
-
CLINICAL_TRIALS withdrawal · 2017-08-10Clinical Trial Update: Safety and Feasibility Study of Mesenchymal Trophic Factor (MTF) for Treatment of Osteoarthritis [Phase 1, Phase 2]
The clinical trial of Mesenchymal Trophic Factor (MTF) for osteoarthritis of the knee in Phase 1/Phase 2 has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2017-08-10Clinical Trial Update: Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating umbilical cord tissue-derived mesenchymal stem cells for osteoarthritis of the knee has been withdrawn…
-
CLINICAL_TRIALS withdrawal · 2017-08-09Clinical Trial Update: A Comparison of Exparel Local Anesthetic in Total Knee Arthroplasty (TKA) Patients [Phase 4]
This Phase 4 trial evaluating Exparel local anesthetic in total knee arthroplasty has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2017-03-10Clinical Trial Update: Intraoperative Liposomal Bupivacaine Injection in Primary Total Knee Arthroplasty [Phase 2, Phase 3]
A Phase 2/3 study evaluating intraoperative liposomal bupivacaine injection in primary total knee arthroplasty was withdrawn.
-
CLINICAL_TRIALS withdrawal · 2016-11-17Clinical Trial Update: Clinical Trial of YY1201 for Treatment of Osteoarthritis of the Knee [Phase 1, Phase 2]
A Phase 1/2 clinical trial of YY1201 for osteoarthritis of the knee has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2015-03-18Clinical Trial Update: Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet [Phase 4]
This Phase 4 clinical trial evaluating primary cemented total knee arthroplasty with versus without tourniquet has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2014-09-17Clinical Trial Update: Biochemical Approach to Measuring Surgical Trauma
The clinical trial NCT01037400 evaluating a biochemical approach to measuring surgical trauma in total knee replacement has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2013-11-13Clinical Trial Update: Efficacy and Safety of Impracor (Ketoprofen 10% Cream) Compared With Placebo in the Treatment of Acute Pain (Flare) Associated With Osteoarthritis of the Knee [Phase 3]
A Phase 3 trial evaluating Impracor (ketoprofen 10% cream) versus placebo for acute pain flares in knee osteoarthritis has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2013-05-01Clinical Trial Update: DePuy Revision TKA Implant 5yr Survivorship
The clinical trial evaluating the five-year survivorship of the DePuy revision total knee arthroplasty implant has been withdrawn. No furthe…
-
CLINICAL_TRIALS withdrawal · 2013-02-07Clinical Trial Update: The Effectiveness of Antibiotic Cement (ABC) Compared to Regular Cement in Reducing the Rate of Infection Following Total Knee Arthroplasty: The ABC Trial [Phase 3]
A Phase 3 trial comparing antibiotic cement to regular cement to reduce infection after total knee arthroplasty has been withdrawn.
-
CLINICAL_TRIALS withdrawal · 2012-01-25Clinical Trial Update: X-Ray Study Investigating The Safety And Efficacy Of SD-6010 In Subjects With Osteoarthritis Of The Knee [Phase 3]
Pfizer reports that the Phase 3 X-ray study of SD-6010 in osteoarthritis of the knee has been withdrawn.